Patricio Soares da-Silva

All papers authored by Patricio Soares da-Silva

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2021 Laura Monni

, Larissa Kraus, Matthias Dipper‐Wawra

, Patricio Soares‐da‐Silva

, Nikolaus Maier

, Dietmar Schmitz

, Martin Holtkamp

, Pawel Fidzinski

In vitro and in vivo anti‐epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2‐related self‐limited epilepsy

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Sarah Schmidt, Leonie Pothmann, Daniel Müller‐Komorowska, Thoralf Opitz, Patrício Soares da Silva

, Heinz Beck

Complex effects of eslicarbazepine on inhibitory micro networks in chronic experimental epilepsy

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2018 Dominik Holtkamp, Thoralf Opitz, Simon Hebeisen, Patrício Soares-Da-Silva

, Heinz Beck

Effects of eslicarbazepine on slow inactivation processes of sodium channels in dentate gyrus granule cells

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Niklas Michael Beckonert

, Thoralf Opitz, Julika Pitsch

, Patrício Soares da Silva

, Heinz Beck

Polyamine modulation of anticonvulsant drug response: A potential mechanism contributing to pharmacoresistance in chronic epilepsy

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2017 Christian Elger, Mathias Koepp, Eugen Trinka, Vicente Villanueva, João Chaves, Elinor Ben-Menachen, Pedro A. Kowacs, António Gil-Nagel, Joana Moreira, Helena Gama, José-Francisco Rocha, Patrício Soares-Da-Silva

Pooled efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Data from four double-blind placebo-controlled pivotal phase III clinical studies

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2015 Bruno Igreja, Lyndon C. Wright, Patricio Soares-Da-Silva

Sustained high blood pressure reduction with etamicastat, a peripheral selective dopamine β-hydroxylase inhibitor

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Heinz Grunze, Eduardo Kotlik, Raquel Costa, Teresa Nunes, Luis Almeida, Amílcar Falcão

, Patrício Soares-Da-Silva

Assessment of the efficacy and safety of eslicarbazepine acetate in acute mania and prevention of recurrence: Experience from multicentre, double-blind, randomised phase II clinical studies in patients with bipolar disorder I

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2014 Bruno Igreja, Patrício Soares da-Silva, Nuno Miguel Pires, Maria João Bonifácio, Ana Isabel Loureiro, Carlos Fernandes-Lopes, Lyndon Christopher Wright, Patrício Soares-Da-Silva

Blood pressure-decreasing effect of etamicastat alone and in combination with antihypertensive drugs in the spontaneously hypertensive rat

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Ana I. Loureiro, Patrício Soares da-Silva, Maria João Bonifácio, Maria João Bonifácio, Carlos Fernandes-Lopes, Bruno Igreja

, Lyndon C. Wright, Patrício Soares-Da-Silva

Etamicastat, a new dopamine-ß-hydroxylase inhibitor, pharmacodynamics and metabolism in rat

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José-Francisco Rocha, Manuel Vaz da-Silva, Patrício Soares da-Silva, Amílcar Falcão

, Ana Santos, Roberto Pinto, Nelson Lopes, Teresa Nunes, Lyndon C. Wright, Manuel Vaz-Da-Silva, Patrício Soares-Da-Silva

Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations

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Sergej Popov, Patricio Soares da-Silva, Hiroshi Takemori, Takeshi Tokudome, Yuanjie Mao, Kentaro Otani, Naoki Mochizuki, Nuno Pires, Maria João Pinho, Anders Franco-Cereceda, Lucia Torielli, Mara Ferrandi, Anders Hamsten, Patricio Soares-Da-Silva

, Per Eriksson and 2 other authors

Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake

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Ana I. Loureiro, Maria João Bonifácio, Carlos Fernandes-Lopes, Bruno Igreja, Nuno Pires, Lyndon Wright, Patrício Soares-Da-Silva

Pharmacokinetic and Pharmacodynamic Properties of Etamicastat, a New DBH Inhibitor

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Patricio Soares-Da-Silva

Novel COMT Inhibitors in Parkinson Disease

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Maria João Bonifácio, Jane Suzanne Sutcliffe, Leonel Torrão, Lyndon Wright, Patrício Soares-Da-Silva

Effect of Opicapone, a New Catechol-O-Methyltransferase Inhibitor, in Levodopa Pharmakokinetics in the Cynomolgous Monkey

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Maria João Bonifácio, Leonel Torrão, Ana Loureiro, Carlos Fernandes-Lopes, Lyndon C. Wright, Patrício Soares-Da-Silva

Pharmacological Profile of Opicapone in Wistar rat

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Simon Hebeisen, Patrício Soares da-Silva, Nuno Pires, Ana I. Loureiro, Maria João Bonifacio, Nuno Palma, Andrew Whyment, David Spanswick, Patricio Soares da Silva

Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: A comparison with carbamazepine, oxcarbazepine and lacosamide

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2013 Heidrun Potschka, Patrício Soares da-Silva, Jonna Soerensen, Anton Pekcec, Ana Loureiro, Patrício Soares-Da-Silva

Effect of eslicarbazepine acetate in the corneal kindling progression and the amygdala kindling model of temporal lobe epilepsy

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Luis Almeida, Patricio Soares da-Silva, Teresa Nunes, Raquel Costa, José F. Rocha, Manuel Vaz da-Silva, Patricio Soares-Da-Silva

Etamicastat, a Novel Dopamine β-Hydroxylase Inhibitor: Tolerability, Pharmacokinetics, and Pharmacodynamics in Patients With Hypertension

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José Francisco Rocha, Ana Santos, Amílcar Falcão

, Nelson Lopes, Teresa Nunes, Roberto Pinto, Patrício Soares da-Silva

Effect of moderate liver impairment on the pharmacokinetics of opicapone

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Ana Fortuna, Gilberto Alves, Patrício Soares-Da-Silva

, Amílcar Falcão

Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: new set of data for predictive in silico ADME models

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All papers authored by Patricio Soares da-Silva