All papers authored by David Shackleford
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2023
Stéphanie Braillard 
,
Martine Keenan ,
Karen J. Breese ,
Jacob Heppell,
Michael Abbott ,
Rafiqul Islam,
David M. Shackleford ,
Kasiram Katneni,
Elly Crighton,
Gong Chen,
Rahul Patil,
Given Lee,
Karen L. White ,
Sandra Carvalho ,
Richard J. Wall
and 23 other authors
,
Martine Keenan ,
Karen J. Breese ,
Jacob Heppell,
Michael Abbott ,
Rafiqul Islam,
David M. Shackleford ,
Kasiram Katneni,
Elly Crighton,
Gong Chen,
Rahul Patil,
Given Lee,
Karen L. White ,
Sandra Carvalho ,
Richard J. Wall
and 23 other authors
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc 1
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2022
M. Lizeth Orozco Morales ,
Catherine A. Rinaldi,
Emma de Jong ,
Sally M. Lansley,
Joel P. A. Gummer ,
Bence Olasz,
Shabarinath Nambiar,
Danika E. Hope ,
Thomas H. Casey ,
Y. C. Gary Lee,
Connull Leslie,
Gareth Nealon,
David M. Shackleford ,
Andrew K. Powell,
Marina Grimaldi
and 7 other authors
Download from doi.org
,
Catherine A. Rinaldi,
Emma de Jong ,
Sally M. Lansley,
Joel P. A. Gummer ,
Bence Olasz,
Shabarinath Nambiar,
Danika E. Hope ,
Thomas H. Casey ,
Y. C. Gary Lee,
Connull Leslie,
Gareth Nealon,
David M. Shackleford ,
Andrew K. Powell,
Marina Grimaldi
and 7 other authors
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2021
Siu Wai Wong ,
Lucy Vivash ,
Ramesh Mudududdla,
Nghi Nguyen ,
Stefan J. Hermans,
David M. Shackleford ,
Judith Field,
Lian Xue,
Andrea Aprico,
Nancy C. Hancock,
Mohammad Haskali,
Michael A. Stashko,
Stephen V. Frye ,
Xiaodong Wang,
Michele D. Binder
and 4 other authors
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,
Lucy Vivash ,
Ramesh Mudududdla,
Nghi Nguyen ,
Stefan J. Hermans,
David M. Shackleford ,
Judith Field,
Lian Xue,
Andrea Aprico,
Nancy C. Hancock,
Mohammad Haskali,
Michael A. Stashko,
Stephen V. Frye ,
Xiaodong Wang,
Michele D. Binder
and 4 other authors
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David I. Finkelstein ,
Jessica L. Billings,
Paul A. Adlard,
Scott Ayton,
Amelia Sedjahtera,
Colin L. Masters,
Simon Wilkins,
David M. Shackleford ,
Susan A. Charman,
Wojciech Bal ,
Izabela A. Zawisza,
Ewa Kurowska,
Andrew L. Gundlach,
Sheri Ma,
Ashley I. Bush
and 8 other authors
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,
Jessica L. Billings,
Paul A. Adlard,
Scott Ayton,
Amelia Sedjahtera,
Colin L. Masters,
Simon Wilkins,
David M. Shackleford ,
Susan A. Charman,
Wojciech Bal ,
Izabela A. Zawisza,
Ewa Kurowska,
Andrew L. Gundlach,
Sheri Ma,
Ashley I. Bush
and 8 other authors
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Benoît Laleu ,
Yuichiro Akao,
Atsuko Ochida,
Sandra Duffy,
Leonardo Lucantoni ,
David M. Shackleford ,
Gong Chen,
Kasiram Katneni,
Francis C. K. Chiu,
Karen L. White,
Xue Chen,
Angelika Sturm,
Koen J. Dechering,
Benigno Crespo,
Laura M. Sanz
and 6 other authors
Download from pubs.acs.org
,
Yuichiro Akao,
Atsuko Ochida,
Sandra Duffy,
Leonardo Lucantoni ,
David M. Shackleford ,
Gong Chen,
Kasiram Katneni,
Francis C. K. Chiu,
Karen L. White,
Xue Chen,
Angelika Sturm,
Koen J. Dechering,
Benigno Crespo,
Laura M. Sanz
and 6 other authors
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David M. Shackleford ,
Francis C. K. Chiu,
Kasiram Katneni,
Scott Blundell,
Jenna McLaren,
Xiaofang Wang,
Lin Zhou,
Kamaraj Sriraghavan,
André M. Alker,
Daniel Hunziker,
Christian Scheurer,
Qingjie Zhao,
Yuxiang Dong ,
Jörg J. Möhrle,
Nada Abla
and 4 other authors
,
Francis C. K. Chiu,
Kasiram Katneni,
Scott Blundell,
Jenna McLaren,
Xiaofang Wang,
Lin Zhou,
Kamaraj Sriraghavan,
André M. Alker,
Daniel Hunziker,
Christian Scheurer,
Qingjie Zhao,
Yuxiang Dong ,
Jörg J. Möhrle,
Nada Abla
and 4 other authors
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
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Aaron G. Poth,
Francis C. K. Chiu,
Sofie Stalmans,
Brett R. Hamilton,
Yen-Hua Huang,
David M. Shackleford ,
Rahul Patil,
Thao T. Le,
Meng-Wei Kan,
Thomas Durek,
Evelien Wynendaele,
Bart De Spiegeleer,
Andrew K. Powell,
Deon J. Venter,
Richard J. Clark
and 2 other authors
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,
Rahul Patil,
Thao T. Le,
Meng-Wei Kan,
Thomas Durek,
Evelien Wynendaele,
Bart De Spiegeleer,
Andrew K. Powell,
Deon J. Venter,
Richard J. Clark
and 2 other authors
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Masanori Okaniwa,
Akira Shibata,
Atsuko Ochida,
Yuichiro Akao,
Karen L. White,
David M. Shackleford ,
Sandra Duffy,
Leonardo Lucantoni ,
Sumanta Dey,
Josefine Striepen,
Tomas Yeo,
Sachel Mok ,
Anna Caroline C. Aguiar,
Angelika Sturm,
Benigno Crespo
and 13 other authors
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,
Sandra Duffy,
Leonardo Lucantoni ,
Sumanta Dey,
Josefine Striepen,
Tomas Yeo,
Sachel Mok ,
Anna Caroline C. Aguiar,
Angelika Sturm,
Benigno Crespo
and 13 other authors
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Michael J. Palmer,
Xiaoyi Deng,
Shawn Watts,
Goran Krilov,
Aleksey Gerasyuto,
Sreekanth Kokkonda,
Farah El Mazouni,
John White,
Karen L. White,
Josefine Striepen,
Jade Bath,
Kyra A. Schindler,
Tomas Yeo,
David M. Shackleford ,
Sachel Mok
and 29 other authors
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,
Sachel Mok
and 29 other authors
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Ryan D. Gillis,
Edoardo Botteri,
Aeson Chang,
Alexandra I. Ziegler ,
Ni-Chun Chung,
Cindy K. Pon ,
David M. Shackleford ,
Bettina K. Andreassen,
Michelle L. Halls,
Jillian G. Baker,
Erica K. Sloan
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,
Ni-Chun Chung,
Cindy K. Pon ,
David M. Shackleford ,
Bettina K. Andreassen,
Michelle L. Halls,
Jillian G. Baker,
Erica K. Sloan
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Sapna Devi,
Yannick O. Alexandre,
Joon Keit Loi,
Ryan Gillis,
Nazanin Ghazanfari,
Sarah J. Creed ,
Lauren E. Holz,
David Shackleford ,
Laura K. Mackay,
William R. Heath ,
Erica K. Sloan,
Scott N. Mueller
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,
Lauren E. Holz,
David Shackleford ,
Laura K. Mackay,
William R. Heath ,
Erica K. Sloan,
Scott N. Mueller
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Daniel L. Priebbenow ,
Mitch Mathiew,
Da-Hua Shi,
Jitendra R. Harjani,
Julia G. Beveridge,
Marina Chavchich,
Michael D. Edstein,
Sandra Duffy,
Vicky M. Avery,
Robert T. Jacobs,
Stephen Brand,
David M. Shackleford ,
Wen Wang,
Longjin Zhong,
Given Lee
and 8 other authors
,
Mitch Mathiew,
Da-Hua Shi,
Jitendra R. Harjani,
Julia G. Beveridge,
Marina Chavchich,
Michael D. Edstein,
Sandra Duffy,
Vicky M. Avery,
Robert T. Jacobs,
Stephen Brand,
David M. Shackleford ,
Wen Wang,
Longjin Zhong,
Given Lee
and 8 other authors
Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines
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Manuela Jörg,
Elham Khajehali,
Emma T. van der Westhuizen,
K. H. C. Choy,
K. H. Christopher Choy,
David M. Shackleford ,
Andrew B. Tobin,
Patrick M. Sexton,
Celine Valant,
Ben Capuano,
Arthur Christopoulos,
Peter J. Scammells
Download from onlinelibrary.wiley.com
,
Andrew B. Tobin,
Patrick M. Sexton,
Celine Valant,
Ben Capuano,
Arthur Christopoulos,
Peter J. Scammells
Download from onlinelibrary.wiley.com
Sreekanth Kokkonda,
Xiaoyi Deng,
Karen L. White,
Farah El Mazouni,
John White,
David M. Shackleford ,
Kasiram Katneni,
Francis C. K. Chiu,
Helena Barker,
Jenna McLaren,
Elly Crighton,
Gong Chen,
Inigo Angulo-Barturen,
Maria Belen Jimenez-Diaz,
Santiago Ferrer
and 14 other authors
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,
Kasiram Katneni,
Francis C. K. Chiu,
Helena Barker,
Jenna McLaren,
Elly Crighton,
Gong Chen,
Inigo Angulo-Barturen,
Maria Belen Jimenez-Diaz,
Santiago Ferrer
and 14 other authors
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Jianbo Wu,
Xiaofang Wang,
Francis C. K. Chiu,
Cécile Häberli,
David M. Shackleford ,
Eileen Ryan,
Sriraghavan Kamaraj,
Vivek J. Bulbule,
Alexander I. Wallick,
Yuxiang Dong ,
Karen L. White,
Paul H. Davis ,
Susan A. Charman,
Jennifer Keiser ,
Jonathan L. Vennerstrom
,
Eileen Ryan,
Sriraghavan Kamaraj,
Vivek J. Bulbule,
Alexander I. Wallick,
Yuxiang Dong ,
Karen L. White,
Paul H. Davis ,
Susan A. Charman,
Jennifer Keiser ,
Jonathan L. Vennerstrom
Structure–Activity Relationship of Antischistosomal Ozonide Carboxylic Acids
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