László Radnai
0000-0001-6843-3740
Scripps Florida
26 papers found
Refreshing results…
Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II
Characterization of the Intramolecular Interactions and Regulatory Mechanisms of the Scaffold Protein Tks4
Solution NMR Structure of the SH3 Domain of Human Caskin1 Validates the Lack of a Typical Peptide Binding Groove and Supports a Role in Lipid Mediator Binding
Advances in Understanding TKS4 and TKS5: Molecular Scaffolds Regulating Cellular Processes from Podosome and Invadopodium Formation to Differentiation and Tissue Homeostasis
A simple and robust cell-based assay for the discovery of novel cytokinesis inhibitors
A Semi-High-Throughput Adaptation of the NADH-Coupled ATPase Assay for Screening Small Molecule Inhibitors
Structural insights into the tyrosine phosphorylation–mediated inhibition of SH3 domain–ligand interactions
EGF Regulates the Interaction of Tks4 with Src through Its SH2 and SH3 Domains
Abl1 SH3 pTyr89/134
Abl2 SH3
Abl2 SH3 pTyr116/161
Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding
The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling
The scaffold protein Tks4 is required for the differentiation of mesenchymal stromal cells (MSCs) into adipogenic and osteogenic lineages
DYNLL2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5a Tail That Has Structural Plasticity
DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail
Ca-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with non- muscle myosin IIA
Ca-bound truncated (delta13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle myosin IIA
Ca2+-bound S100A4 C3S, C81S, C86S and F45W mutant complexed with myosin IIA
Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism
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