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All papers authored by Shannon M. Reilly

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2024 Wenmin Xia

ORCID

, Preethi Veeragandham, Yu Cao

ORCID

, Yayun Xu, Torrey E. Rhyne, Jiaxin Qian, Chao-Wei Hung

ORCID

ORCID

, Ying Jones, Hui Gao

ORCID

, Christopher Liddle, Ruth T. Yu

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, Michael Downes, Ronald M. Evans

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, Mikael Rydén

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and 7 other authors

Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation

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2021 Omer Keinan, Joseph M. Valentine, Haopeng Xiao

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, Sushil K. Mahata, Shannon M. Reilly

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, Mohammad Abu-Odeh, Julia H. Deluca, Benyamin Dadpey

ORCID

, Leslie Cho, Austin Pan, Ruth T. Yu

ORCID

, Yang Dai, Christopher Liddle

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, Michael Downes, Ronald M. Evans

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and 6 other authors

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

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Jing Yong

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, Vishal S. Parekh

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, Shannon M. Reilly

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, Jonamani Nayak, Zhouji Chen, Cynthia Lebeaupin

ORCID

ORCID

, Jiangwei Zhang, Thazha P. Prakash

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, Hong Sun, Sue Murray

ORCID

ORCID

, Julio E. Ayala

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, Leslie S. Satin, Alan R. Saltiel

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and 1 other authors

Chop / Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice

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Mohammad Abu-Odeh, Yuan Zhang, Shannon M. Reilly

ORCID

, Nima Ebadat, Omer Keinan, Joseph M. Valentine, Maziar Hafezi-Bakhtiari, Hadeel Ashayer, Lana Mamoun, Xin Zhou, Jin Zhang, Ruth T. Yu, Yang Dai, Christopher Liddle, Michael Downes and 4 other authors

FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes

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Shannon M. Reilly

ORCID

, Mohammad Abu-Odeh, Magdalene Ameka, Julia H. DeLuca

ORCID

, Meghan C. Naber, Benyamin Dadpey, Nima Ebadat, Andrew V. Gomez

ORCID

, Xiaoling Peng, BreAnne Poirier, Elyse Walk, Matthew J. Potthoff

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, Alan R. Saltiel

ORCID

FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition

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2020 Jin Young Huh

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, Shannon M. Reilly

ORCID

, Mohammad Abu-Odeh, Anne N. Murphy, Sushil K. Mahata, Jinyu Zhang, Yoori Cho, Jong Bae Seo, Chao-Wei Hung, Courtney R. Green, Christian M. Metallo, Alan R. Saltiel

TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

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Shannon M. Reilly

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, Chao-Wei Hung, Maryam Ahmadian, Peng Zhao

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, Omer Keinan, Andrew V. Gomez

ORCID

, Julia H. DeLuca, Benyamin Dadpey, Donald Lu, Jessica Zaid, BreAnne Poirier, Xiaoling Peng, Ruth T. Yu, Michael Downes, Christopher Liddle

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and 3 other authors

Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3

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2019 Lirui Wang, Magdalena Mazagova, Chuyue Pan, Song Yang, Katharina Brandl, Jun Liu, Shannon M. Reilly

ORCID

, Yanhan Wang, Zhaorui Miao, Rohit Loomba, Na Lu, Qinglong Guo, Jihua Liu, Ruth T. Yu, Michael Downes and 5 other authors

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity

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2018 Tyler S. Beyett, Xinmin Gan, Shannon M. Reilly

ORCID

, Andrew V. Gomez, Louise Chang, John J. G. Tesmer, Alan R. Saltiel, Hollis D. Showalter

Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity

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Tyler S. Beyett

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, Xinmin Gan, Shannon M. Reilly

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, Louise Chang, Andrew V. Gomez, Alan R. Saltiel, Hollis D. Showalter, John J. G. Tesmer

Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition

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Yuliya Skorobogatko, Morgan Dragan, Claudia Cordon, Shannon M. Reilly

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, Chao-Wei Hung, Wenmin Xia, Peng Zhao, Martina Wallace

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, Denise E. Lackey, Xiao-Wei Chen, Olivia Osborn, Juliane G. Bogner-Strauss, Dan Theodorescu, Christian M. Metallo, Jerrold M. Olefsky and 1 other authors

RalA controls glucose homeostasis by regulating glucose uptake in brown fat

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Chun-Seok Cho

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, Hwan-Woo Park

ORCID

, Allison Ho, Ian A. Semple, Boyoung Kim, Insook Jang, Haeli Park, Shannon Reilly

ORCID

, Alan R. Saltiel, Jun Hee Lee

Lipotoxicity induces hepatic protein inclusions through TANK binding kinase 1-mediated p62/sequestosome 1 phosphorylation

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Maryam Ahmadian, Sihao Liu, Shannon M. Reilly

ORCID

, Nasun Hah, Weiwei Fan, Eiji Yoshihara, Pooja Jha, C. Daniel De Magalhaes Filho, Sandra Jacinto, Andrew V. Gomez, Yang Dai, Ruth T. Yu, Christopher Liddle, Annette R. Atkins, Johan Auwerx and 3 other authors

ERRγ Preserves Brown Fat Innate Thermogenic Activity

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Peng Zhao, Kai in Wong, Xiaoli Sun, Shannon M. Reilly

ORCID

, Maeran Uhm, Zhongji Liao, Yuliya Skorobogatko, Alan R. Saltiel

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue

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2017 Shannon M. Reilly

ORCID

, Alan R. Saltiel

Adapting to obesity with adipose tissue inflammation

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Elif A. Oral, Shannon M. Reilly

ORCID

, Andrew V. Gomez, Rasimcan Meral, Laura Butz, Nevin Ajluni, Thomas L. Chenevert, Evgenia Korytnaya, Adam H. Neidert, Rita Hench, Diana Rus, Jeffrey F. Horowitz, BreAnne Poirier, Peng Zhao, Kim Lehmann and 7 other authors

Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes

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2015 Shannon M. Reilly

ORCID

, Alan R. Saltiel

ORCID

A Futile Approach to Fighting Obesity?

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Shannon M. Reilly

ORCID

, Maryam Ahmadian, Brian F. Zamarron, Louise Chang, Maeran Uhm, BreAnne Poirier, Xiaoling Peng, Danielle M. Krause, Evgenia Korytnaya, Adam Neidert, Christopher Liddle, Ruth T. Yu, Carey N. Lumeng, Elif A. Oral, Michael Downes and 2 other authors

A subcutaneous adipose tissue–liver signalling axis controls hepatic gluconeogenesis

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Sungsoon Fang, Jae Myoung Suh, Shannon M. Reilly

ORCID

, Elizabeth Yu, Olivia Osborn, Denise Lackey, Eiji Yoshihara, Alessia Perino, Sandra Jacinto, Yelizaveta Lukasheva, Annette R. Atkins, Alexander Khvat, Bernd Schnabl, Ruth T. Yu

ORCID

, David A. Brenner and 7 other authors

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

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2014 Shannon M. Reilly

ORCID

, Alan R. Saltiel

ORCID

Countering inflammatory signals in obesity

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