M. Matilde Marques

All papers authored by M. Matilde Marques

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2020 Madalena Cipriano

, Pedro F. Pinheiro, Catarina O. Sequeira, Joana S. Rodrigues

, Nuno G. Oliveira, Alexandra M. M. Antunes

, Matilde Castro, M. Matilde Marques

, Sofia A. Pereira

, Joana P. Miranda

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model

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2019 Aline T. Marinho

, Joana P. Miranda

, Umbelina Caixas

, Catarina Charneira

, Clara Gonçalves-Dias

, M. Matilde Marques

, Emília C. Monteiro

, Alexandra M. M. Antunes

, Sofia A. Pereira

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity

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2016 Nádia M. Grilo, M. João Correia, Catarina Sequeira, Shrika G. Harjivan, Umbelina Caixas, Lucília N. Diogo, M. Matilde Marques

, Emília C. Monteiro, Alexandra M. M. Antunes, Sofia A. Pereira

Efavirenz biotransformation as an up-stream event of mood changes in HIV-infected patients

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Pedro F. Pinheiro, Sofia A. Pereira, Shrika G. Harjivan, Inês L. Martins, Aline T. Marinho, Madalena Cipriano, Cristina C. Jacob, Nuno G. Oliveira, Matilde F. Castro, M. Matilde Marques

, Alexandra M. M. Antunes, Joana P. Miranda

Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study

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Aline T. Marinho, Clara G. Dias, Pedro F. Pinheiro, Ana Rita Lemos, Alexandra M. M. Antunes, M. Matilde Marques

, Emília C. Monteiro, Joana P. Miranda

, Sofia A. Pereira

Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach

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2015 Frederick A. Beland, Greg R. Olson, Maria C. B. Mendoza, M. Matilde Marques

, Daniel R. Doerge

Carcinogenicity of glycidamide in B6C3F 1 mice and F344/N rats from a two-year drinking water exposure

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I. Martins, M. M. Marques

, A. Antunes

Protein adducts from carbamazepine-10,11-epoxide, the major metabolite of the antiepileptic drug carbamazepine: possible biomarkers of toxicity

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A. Godinho, G. Surratt, G. Gamboa da Costa, G. Gamboa da Costa, F. A. Beland, A. M. M. Antunes, M. M. Marques

Metabolic activation of the nevirapine metabolite 12-hydroxy-nevirapine to 12-formylnevirapine – A possible factor in nevirapine toxicity

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S. G. Harjivan, P. F. Pinheiro, I. L. Martins, D. A. Novais, R. Wanke, P. P. Santos, S. A. Pereira, F. A. Beland, M. M. Marques

, A. M. M. Antunes

Enzymatic bioactivation of the phenolic nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine to quinoid intermediates: Covalent adduct formation with nitrogen-based amino acids

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S. G. Harjivan, R. Wanke, K. Woodling, G. Gamboa da Costa, G. Gamboa da Costa, F. A. Beland, A. M. M. Antunes, M. M. Marques

First in vitro evidence for a catechol metabolite from the anti-HIV drug efavirenz – A plausible role in toxicity

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M. Y. Mahgoub, L. Cavaca, F. A. Beland, M. M. Marques

Activation of aloe-emodin to biologically plausible electrophiles – Possible role in the carcinogenicity of aloe vera whole leaf extracts

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P. F. Pinheiro, A. T. Marinho, A. M. M. Antunes, M. M. Marques

, S. A. Pereira, J. P. Miranda

Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats

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Shrika G. Harjivan, Pedro F. Pinheiro, Inês L. Martins, Ana L. Godinho, Riccardo Wanke, Pedro P. Santos, Sofia A. Pereira, Frederick A. Beland, M. Matilde Marques

, Alexandra M. M. Antunes

Quinoid derivatives of the nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine: activation pathway to amino acid adducts

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J. L. Ferreira da Silva, Shrika G. Harjivan, André P. Ferreira, Karina Shimizu

, M. Matilde Marques

, M. Teresa Duarte

Effect of substituents in the molecular and supramolecular architectures of 1-ferrocenyl-2-(aryl)thioethanones

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2014 Nádia M. Grilo, Vânia L. Batalha, Luisa V. Lopes, M. Matilde Marques

, Emília C. Monteiro, Alexandra M. M. Antunes, Sofia A. Pereira

An animal model to explore efavirenz toxicokinetics and its relation to neurological phenotype

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Shrika G. Harjivan, Riccardo Wanke, João L. Ferreira da Silva, M. Matilde Marques

, Alexandra M. M. Antunes

The phenolic metabolites of the anti-HIV drug efavirenz: Evidence for distinct reactivities upon oxidation with Frémy's salt

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Aline T. Marinho, Ana L. A. Godinho, David A. Novais, Alexandra M. M. Antunes, M. Matilde Marques

, Teresa Ramos

, Clara G. Dias, Emília C. Monteiro, Sofia A. Pereira

Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Shrika G. Harjivan, Catarina Charneira, Sofia A. Pereira, Guadalupe Espadas, Eduard Sabido

, Frederick A. Beland, M. Matilde Marques

, Alexandra M. M. Antunes

Covalent histone modification by nevirapine: Potential association with non-AIDS defining cancers

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Nádia M. Grilo, Catarina Charneira, Sofia A. Pereira, Emília C. Monteiro, M. Matilde Marques

, Alexandra M. M. Antunes

Bioactivation to an aldehyde metabolite—Possible role in the onset of toxicity induced by the anti-HIV drug abacavir

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2013 Riccardo Wanke, Shrika G. Harjivan, Sofia A. Pereira, M. Matilde Marques

, Alexandra M. M. Antunes

The role of competitive binding to human serum albumin on efavirenz–warfarin interaction: a nuclear magnetic resonance study

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All papers authored by M. Matilde Marques