Frederick Buckner

Papers authored by Frederick Buckner

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2009 Swati Mandal, Mahendra Maharjan, Sudipto Ganguly, Mitali Chatterjee, Sarman Singh, Frederick S. Buckner

, Rentala Madhubala

High-throughput screening of amastigotes of Leishmania donovani clinical isolates against drugs using a colorimetric β-lactamase assay

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Praveen Kumar Suryadevara, Srinivas Olepu, Jeffrey W. Lockman, Junko Ohkanda, Mandana Karimi, Christophe L. M. J. Verlinde, James M. Kraus, Jan Schoepe, Wesley C. Van Voorhis, Andrew D. Hamilton, Frederick S. Buckner

, Michael H. Gelb

Structurally Simple Inhibitors of Lanosterol 14α-Demethylase Are Efficacious In a Rodent Model of Acute Chagas Disease

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Gregory J. Crowther, Wesley C. van Voorhis, Alberto J. Napuli, Andrew P. Thomas, Diana J. Chung, Kuzma V. Kovzun, David J. Leibly, Lisa J. Castaneda, Janhavi Bhandari, Christopher J. Damman, Raymond Hui, Wim G. J. Hol, Frederick S. Buckner

, Christophe L. M. J. Verlinde, Zhongsheng Zhang and 1 other authors

Buffer Optimization of Thermal Melt Assays of Plasmodium Proteins for Detection of Small-Molecule Ligands

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Ramesh Gujjar, Alka Marwaha, Farah El Mazouni, Farah El Mazouni, John White, Karen L. White, Sharon Creason, David M. Shackleford

, Jeffrey Baldwin, William N. Charman, Frederick S. Buckner

, Susan Charman, Pradipsinh K. Rathod, Margaret A. Phillips

Identification of a Metabolically Stable Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Antimalarial Activity in Mice

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Esther Bettiol, Marie Samanovic, Andrew S. Murkin, Jayne Raper, Frederick Buckner

, Ana Rodriguez

Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

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James M. Kraus, Christophe Lmj M. J. Verlinde, Mandana Karimi, Galina I. Lepesheva, Michael H. Gelb, Frederick S. Buckner

Rational Modification of a Candidate Cancer Drug for Use Against Chagas Disease

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Eduardo Caio Torres-Santos, Maria Isabel Sampaio-Santos, Frederick S. Buckner

, Kohei Yokoyama, Michael Gelb, Julio A. Urbina, Bartira Rossi-Bergmann

Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone

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This paper was not found in any repository, but could be made available legally by the author.

John B. M. D. Zabriskie, Allan M. D. Gibofsky, Wesley C. M. D. Van Voorhis, Frederick S. M. D. Buckner

, Noel R. M. D. Rose

Immunological Aspects of Cardiac Disease

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Christophe L. M. J. Verlinde, Erkang K. Fan, Sayaka Shibata, Zongsheng S. Zhang, Zhihua H. Sun, Wei Deng, Jennifer Ross, Jessica Kim, Liren R. Xiao, Tracy L. Arakaki, Jürgen Bosch

, Jonathan M. Caruthers, Eric T. Larson, Isolde LeTrong, Alberto Napuli and 8 other authors

Fragment-based cocktail crystallography by the Medical Structural Genomics of Pathogenic Protozoa Consortium

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

J. M. Kraus, C. L. M. J. Verlinde, M. Karimi, G. I. Lepesheva, M. H. Gelb, F. S. Buckner

Rational modification of a candidate cancer drug for use against Chagas disease (Journal of Medicinal Chemistry (2009) 52, (1639) DOI: 10.1021/jm801313t)

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2008 Fernán Agüero

, Bissan Al-Lazikani, Martin Aslett, Matthew Berriman, Frederick S. Buckner

, Robert K. Campbell, Santiago Carmona

, Ian M. Carruthers, Buckner Fs, A. W. Edith Chan, Feng Chen, Gregory J. Crowther, Maria A. Doyle, Campbell Rk, Christiane Hertz-Fowler and 20 other authors

Genomic-scale prioritization of drug targets: the TDR Targets database

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Kayode K. Ojo, J. Robert Gillespie, Aaron J. Riechers, Alberto J. Napuli, Christophe L. M. J. Verlinde, Frederick S. Buckner

, Michael H. Gelb, Mathias M. Domostoj, Susan J. Wells, Alexander Scheer, Timothy N. C. Wells, Wesley C. Van Voorhis

Glycogen Synthase Kinase 3 Is a Potential Drug Target for African Trypanosomiasis Therapy

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Frederick S. Buckner

Sterol 14-Demethylase Inhibitors for Trypanosoma cruzi Infections

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Steven Fletcher, Cg Cummings, Kasey Rivas, Wp Katt, Carrie Hornéy, Fs Buckner

, Debopam Chakrabarti, Sm Sebti, Mh Gelb, Wc Van Voorhis, Ad Hamilton

Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validation.

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Eric T. Larson, Wei Deng, Brian E. Krumm, Alberto Napuli, Natascha Mueller, Wesley C. Van Voorhis, Frederick S. Buckner

, Erkang Fan, Angela Lauricella, George DeTitta, Joseph Luft, Frank Zucker, Wim G. J. Hol, Christophe L. M. J. Verlinde, Ethan A. Merritt

Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity

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Ethan A. Merritt, Margaret Holmes, Frederick S. Buckner

, Wesley C. Van Voorhis, Erin Quartly, Eric M. Phizicky, Angela Lauricella, Joseph Luft, George DeTitta, Helen Neely, Frank Zucker, Wim G. J. Hol

Structure of aTrypanosoma bruceiα/β-hydrolase fold protein with unknown function

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Tracy L. Arakaki, Frederick S. Buckner

, J. Robert Gillespie, J. Robert Gillespie, Nicholas A. Malmquist

, Margaret A. Phillips, Oleksandr Kalyuzhniy, Joseph R. Luft, George T. DeTitta, Christophe L. M. J. Verlinde, Wesley C. Van Voorhis, Wim G. J. Hol, Ethan A. Merritt

Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies

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Erkang Fan, David Baker, Stanley Fields, Michael H. Gelb, Frederick S. Buckner

, Wesley C. Van Voorhis, Wesley C. Voorhis, Eric Phizicky, Mark Dumont, Christopher Mehlin, Elizabeth Grayhack, Mark Sullivan, Christophe Verlinde, George Detitta, Deirdre R. Meldrum and 29 other authors

Structural Genomics of Pathogenic Protozoa: an Overview

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2007 Kohei Yokoyama, John R. Gillespie, Wesley C. Van Voorhis, Frederick S. Buckner

, Michael H. Gelb

Protein geranylgeranyltransferase-I of Trypanosoma cruzi

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Pravin Bendale, Srinivas Olepu, Praveen Kumar Suryadevara, Vivek Bulbule, Kasey Rivas, Laxman Nallan, Brian Smart, Kohei Yokoyama, Sudha Ankala, Prakash Rao Pendyala, David Floyd, Louis J. Lombardo, David K. Williams, Frederick S. Buckner

, Debopam Chakrabarti and 3 other authors

Second Generation Tetrahydroquinoline-Based Protein Farnesyltransferase Inhibitors as Antimalarials

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Papers authored by Frederick Buckner