All papers authored by Guillaume Lessene
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2022
Donia M. Moujalled,
Fiona C. Brown 
,
Chong Chyn Chua ,
Michael A. Dengler ,
Giovanna Pomilio,
Natasha S. Anstee ,
Veronique Litalien,
Ella R. Thompson,
Thomas David Morley,
Sarah MacRaild,
Ing Soo Tiong ,
Rhiannon Morris ,
Karen Dun,
Adrian Carl Zordan,
Jaynish S. Shah
and 10 other authors
,
Chong Chyn Chua ,
Michael A. Dengler ,
Giovanna Pomilio,
Natasha S. Anstee ,
Veronique Litalien,
Ella R. Thompson,
Thomas David Morley,
Sarah MacRaild,
Ing Soo Tiong ,
Rhiannon Morris ,
Karen Dun,
Adrian Carl Zordan,
Jaynish S. Shah
and 10 other authors
Acquired mutations in BAX confer resistance to BH3-mimetic therapy in Acute Myeloid Leukemia
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Diane Moujalled ,
Adam G. Southon,
Eiman Saleh,
Kerstin Brinkmann ,
Francine Ke ,
Melinda Iliopoulos ,
Ryan S. Cross,
Misty R. Jenkins ,
Duong Nhu,
Zilu Wang,
Melissa X. Shi ,
Ruth M. Kluck ,
Guillaume Lessene ,
Stephanie Grabow,
Ashley I. Bush
and 1 other authors
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,
Adam G. Southon,
Eiman Saleh,
Kerstin Brinkmann ,
Francine Ke ,
Melinda Iliopoulos ,
Ryan S. Cross,
Misty R. Jenkins ,
Duong Nhu,
Zilu Wang,
Melissa X. Shi ,
Ruth M. Kluck ,
Guillaume Lessene ,
Stephanie Grabow,
Ashley I. Bush
and 1 other authors
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2021
Yanxiang Meng ,
Katherine A. Davies ,
Cheree Fitzgibbon,
Samuel N. Young,
Sarah E. Garnish,
Christopher R. Horne ,
Cindy Luo,
Jean-Marc Garnier,
Lung-Yu Liang,
Angus D. Cowan ,
Andre L. Samson ,
Guillaume Lessene ,
Jarrod J. Sandow ,
Peter E. Czabotar ,
James M. Murphy
,
Katherine A. Davies ,
Cheree Fitzgibbon,
Samuel N. Young,
Sarah E. Garnish,
Christopher R. Horne ,
Cindy Luo,
Jean-Marc Garnier,
Lung-Yu Liang,
Angus D. Cowan ,
Andre L. Samson ,
Guillaume Lessene ,
Jarrod J. Sandow ,
Peter E. Czabotar ,
James M. Murphy
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
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2020
Kerstin Brinkmann ,
Paul Waring,
Stefan P. Glaser,
Verena Wimmer,
Denny L. Cottle,
Ming Shen Tham,
Duong Nhu,
Lachlan Whitehead,
Alex Rd Delbridge,
Guillaume Lessene ,
Ian M. Smyth ,
Marco J. Herold ,
Gemma L. Kelly,
Stephanie Grabow,
Andreas Strasser
,
Paul Waring,
Stefan P. Glaser,
Verena Wimmer,
Denny L. Cottle,
Ming Shen Tham,
Duong Nhu,
Lachlan Whitehead,
Alex Rd Delbridge,
Guillaume Lessene ,
Ian M. Smyth ,
Marco J. Herold ,
Gemma L. Kelly,
Stephanie Grabow,
Andreas Strasser
BCL‐XL exerts a protective role against anemia caused by radiation‐induced kidney damage
Download from onlinelibrary.wiley.com
Theresa Klemm ,
Gregor Ebert,
Dale J. Calleja ,
Cody C. Allison,
Lachlan W. Richardson ,
Jonathan P. Bernardini ,
Bernadine Gc Lu ,
Nathan W. Kuchel,
Christoph Grohmann,
Yuri Shibata,
Zhong Yan Gan ,
James P. Cooney ,
Marcel Doerflinger ,
Amanda E. Au ,
Timothy R. Blackmore
and 15 other authors
,
Gregor Ebert,
Dale J. Calleja ,
Cody C. Allison,
Lachlan W. Richardson ,
Jonathan P. Bernardini ,
Bernadine Gc Lu ,
Nathan W. Kuchel,
Christoph Grohmann,
Yuri Shibata,
Zhong Yan Gan ,
James P. Cooney ,
Marcel Doerflinger ,
Amanda E. Au ,
Timothy R. Blackmore
and 15 other authors
Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2
Download from onlinelibrary.wiley.com
2019
Mark F. van Delft ,
Stephane Chappaz ,
Yelena Khakham,
Chinh T. Bui,
Marlyse A. Debrincat,
Kym N. Lowes,
Jason M. Brouwer,
Christoph Grohmann,
Phillip P. Sharp,
Laura F. Dagley ,
Lucy Li,
Kate McArthur ,
Meng-Xiao Luo,
Hui San Chin ,
W. Douglas Fairlie
and 21 other authors
,
Stephane Chappaz ,
Yelena Khakham,
Chinh T. Bui,
Marlyse A. Debrincat,
Kym N. Lowes,
Jason M. Brouwer,
Christoph Grohmann,
Phillip P. Sharp,
Laura F. Dagley ,
Lucy Li,
Kate McArthur ,
Meng-Xiao Luo,
Hui San Chin ,
W. Douglas Fairlie
and 21 other authors
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
Download from www.nature.com
Richard W. Birkinshaw ,
Jia-Nan Gong,
Cindy S. Luo,
Daisy Lio,
Christine A. White ,
Mary Ann Anderson,
Piers Blombery,
Guillaume Lessene ,
Ian J. Majewski ,
Rachel Thijssen,
Andrew W. Roberts ,
David C. S. Huang,
Peter M. Colman,
Peter E. Czabotar
,
Jia-Nan Gong,
Cindy S. Luo,
Daisy Lio,
Christine A. White ,
Mary Ann Anderson,
Piers Blombery,
Guillaume Lessene ,
Ian J. Majewski ,
Rachel Thijssen,
Andrew W. Roberts ,
David C. S. Huang,
Peter M. Colman,
Peter E. Czabotar
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
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2018
Margs S. Brennan ,
Catherine Chang,
Lin Tai,
Guillaume Lessene ,
Andreas Strasser ,
Grant Dewson,
Gemma L. Kelly,
Marco J. Herold
Download from ashpublications.org
,
Catherine Chang,
Lin Tai,
Guillaume Lessene ,
Andreas Strasser ,
Grant Dewson,
Gemma L. Kelly,
Marco J. Herold
Download from ashpublications.org
Emma J. Petrie,
Jarrod J. Sandow,
Annette V. Jacobsen ,
Brian J. Smith ,
Michael D. W. Griffin,
Isabelle S. Lucet,
Weiwen Dai,
Samuel N. Young,
Maria C. Tanzer,
Ahmad Wardak,
Lung-Yu Liang,
Angus D. Cowan ,
Joanne M. Hildebrand,
Wilhelmus J. A. Kersten,
Guillaume Lessene
and 4 other authors
Download from www.nature.com
,
Brian J. Smith ,
Michael D. W. Griffin,
Isabelle S. Lucet,
Weiwen Dai,
Samuel N. Young,
Maria C. Tanzer,
Ahmad Wardak,
Lung-Yu Liang,
Angus D. Cowan ,
Joanne M. Hildebrand,
Wilhelmus J. A. Kersten,
Guillaume Lessene
and 4 other authors
Download from www.nature.com
2016
Jia-Nan Gong ,
Tiffany Khong,
David Segal ,
Yuan Yao,
Chris D. Riffkin,
Jean-Marc Garnier,
Seong Lin Khaw,
Guillaume Lessene ,
Andrew Spencer,
Marco J. Herold ,
Andrew W. Roberts ,
David C. S. Huang
,
Tiffany Khong,
David Segal ,
Yuan Yao,
Chris D. Riffkin,
Jean-Marc Garnier,
Seong Lin Khaw,
Guillaume Lessene ,
Andrew Spencer,
Marco J. Herold ,
Andrew W. Roberts ,
David C. S. Huang
Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1
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