Michael Wakelam - Dissemin

Papers authored by Michael Wakelam

This paper is made freely available by the publisher.

2002 Elizabeth M. Deacon, Trevor R. Pettitt, Paul Webb, Timothy Cross, Hema Chahal, Michael J. O. Wakelam

, Janet M. Lord

Generation of diacylglycerol molecular species through the cell cycle: a role for 1-stearoyl, 2-arachidonyl glycerol in the activation of nuclear protein kinase C-βII at G2/M

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George S. Baillie, Elaine Huston, Grant Scotland, Matt Hodgkin, Irene Gall, Alex H. Peden, Carolynn MacKenzie, Emma S. Houslay, Richard Currie, Trevor R. Pettitt, Adrian R. Walmsley, Michael J. O. Wakelam

, Jim Warwicker, Miles D. Houslay, Huston E Scotland G Hodgkin M Gall I Peden AH MacKenzie C Houslay ES Currie R Pettitt TR Walmsley AR Wakelam MJ Warwicker J Houslay Baillie Gs

TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid.

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2001 Trevor R. Pettitt, Mark McDermott, Khalid M. Saqib, Neil Shimwell, Michael J. O. Wakelam

Phospholipase D1b and D2a generate structurally identical phosphatidic acid species in mammalian cells.

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Richard J. Woodfield, Matthew N. Hodgkin, Nasreen Akhtar, Mary A. Morse, Kerensa J. Fuller, Khalid Saqib, Neil T. Thompson, Michael J. O. O. Wakelam

The p85 subunit of phosphoinositide 3-kinase is associated with β-catenin in the cadherin-based adhesion complex

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Anne Ben Smith, Stephen K. Dove, Ashley Martin, Michael J. O. Wakelam

, Caroline O. S. Savage

Antineutrophil cytoplasm autoantibodies from patients with systemic vasculitis activate neutrophils through distinct signaling cascades: comparison with conventional Fcγ receptor ligation

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Simon A. Rudge, Trevor R. Pettitt, Chun Zhou, Michael J. O. Wakelam

, JoAnne A. Engebrecht

SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae.

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This paper is available in a repository.

2000 D. R. Ferry, M. Deakin, J. Baddeley, S. Daryanani, S. Bramhall, D. A. Anderson, M. J. O. Wakelam

, J. Doran, G. Pemberton, A. M. Young, J. Buckels, D. J. Kerr

A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: Correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints

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Caroline A. Millar, Timo Meerloo, Sally Martin, Gilles R. X. Hickson, Neil J. Shimwell, Michael J. O. Wakelam

, David E. James, Gwyn W. Gould

Adipsin and the glucose transporter GLUT4 traffic to the cell surface via independent pathways in adipocytes

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Matthew N. Hodgkin, Margaret R. Masson, Dale Powner, Khalid M. Saqib, Christopher P. Ponting

, Michael J. O. Wakelam

Phospholipase D regulation and localisation is dependent upon a phosphatidylinositol 4,5-bisphosphate-specific PH domain

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

M. J. Cross, M. N. Hodgkin, S. Roberts, E. Landgren, M. J. O. Wakelam

, L. Claesson-Welsh

Tyrosine 766 in the fibroblast growth factor receptor-1 is required for FGF-stimulation of phospholipase C, phospholipase D, phospholipase A 2, phosphoinositide 3-kinase and cytoskeletal reorganisation in porcine aortic endothelial cells

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1999 Trevor R. Pettitt, Michael J. O. Wakelam

Diacylglycerol Kinase ε, but Not ζ, Selectively Removes Polyunsaturated Diacylglycerol, Inducing Altered Protein Kinase C Distribution in Vivo

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David R. Jones, Trevor R. Pettitt, Miguel A. Sanjuan, Sanjuan Ma, Isabel Mérida, Michael J. O. O. Wakelam

, M. J. O Wakelam

Interleukin-2 Causes an Increase in Saturated/Monounsaturated Phosphatidic Acid Derived from 1,2-Diacylglycerol and 1-O-Alkyl-2-acylglycerol

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Nicholas J. Pumphrey, Vanessa Taylor, Sylvie Freeman

, Michael R. Douglas, Paul F. Bradfield, Stephen P. Young, Janet M. Lord, Michael J. O. Wakelam

, Ian N. Bird, Michael Salmon, Christopher D. Buckley

Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-γ1 with PECAM-1/CD31

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Matthew N. Hodgkin, Joanna M. Clark, Sally Rose, Khalid Saqib, Michael J. O. Wakelam

Characterization of the regulation of phospholipase D activity in the detergent-insoluble fraction of HL60 cells by protein kinase C and small G-proteins.

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Jonathan J. Gilbert, Trevor R. Pettitt, Sandra D. Seatter, Steven D. Reid, Michael J. O. Wakelam

, Margaret M. Harnett

Antagonistic roles for phospholipase D activities in B cell signaling: While the antigen receptors transduce mitogenic signals via a novel phospholipase D activity, phosphatidylcholine-phospholipase D mediates antiproliferative signals

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B. D. Levy, Fokin, J. M. Clark, M. J. O. Wakelam

, N. A. Petasis, C. N. Serhan

Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: A 'stop' signaling switch for aspirin-triggered lipoxin A 4

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This paper was not found in any repository, but could be made available legally by the author.

Caroline A. Millar, Thomas J. Jess, Khalid M. Saqib, Michael J. O. Wakelam

, Gwyn W. Gould

3T3-L1 Adipocytes Express Two Isoforms of Phospholipase D in Distinct Subcellular Compartments

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1998 Michael J. O. Wakelam

Diacylglycerol - When is it an intracellular messenger?

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Michael J. O. Wakelam

, Margaret M. Harnett

Phospholipase A2 (EC3.1.1.4) and D (EC3.1.4.4) signalling in lymphocytes

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Fraser D. Brown, Khalid M. Saqib, Joanna M. Clark, Neil T. Thompson, Nicola T. Thompson, Dale Powner, Roberto Solari, Michael J. O. Wakelam

Phospholipase D1 localises to secretory granules and lysosomes and is plasma-membrane translocated on cellular stimulation

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Papers authored by Michael Wakelam