Klas Wiman - Dissemin

Papers authored by Klas Wiman

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2015 Cinzia Bersani, Mikael Huss, Stefania Giacomello, Li-Di Xu, Li Di Xu, Julie Bianchi, Sofi Eriksson, Fredrik Jerhammar, Andrey Alexeyenko

, Anna Vilborg, Joakim Lundeberg, Weng-Onn Lui, Klas G. Wiman

Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis

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David S. H. Liu, Walid J. Azar, Carleen Cullinane, Matthew Read, Christina M. Fennell, Karen G. Montgomery, Sue Haupt, Ygal Haupt, Klas G. Wiman

, Cuong P. Duong, Nicholas J. Clemons, Wayne A. Phillips

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

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T. Soussi, K. G. Wiman

TP53: An oncogene in disguise

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N. Mohell, J. Alfredsson, A. Fransson, Å. Fransson, M. Uustalu, S. Bystrom, Joachim Gullbo, Anders Hallberg, V. J. N. Bykov, U. Bjorklund, K. G. Wiman

APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells

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2014 Li Di Xu, Li-Di Xu, Susanne Muller, Srinivasan R. Thoppe, Fredrik Hellborg, Lena Kanter, Mikael Lerner, Biying Zheng, Svetlana Bajalica Lagercrantz, Dan Grandér, Keng Ling Wallin, Klas G. Wiman

, Catharina Larsson, Sonia Andersson

Expression of the p53 Target Wig-1 Is Associated with HPV Status and Patient Survival in Cervical Carcinoma

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Vladimir J. N. Bykov, Klas G. Wiman

Mutant p53 reactivation by small molecules makes its way to the clinic

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C. Bersani, L.-D. Xu, A. Vilborg, W.-O. Lui, K. G. Wiman

Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ

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Gemma L. Kelly, Stephanie Grabow, Stefan P. Glaser, Leah Fitzsimmons, Brandon J. Aubrey, Toru Okamoto, Liz J. Valente, Mikara Robati, Lin Tai, W. Douglas Fairlie, Erinna F. Lee, Mikael S. Lindstrom

, Klas G. Wiman

, David C. S. Huang, Philippe Bouillet and 4 other authors

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

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2013 X. Peng, M.-Q.-Z. Zhang, F. Conserva, G. Hosny, G. Selivanova, V. J. N. Bykov, E. S. J. Arnér, K. G. Wiman

APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

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K. G. Wiman

p53 talks to PARP: the increasing complexity of p53-induced cell death

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Ruby Shalom-Feuerstein, Laura Serror, Edith Aberdam, Franz-Josef Müller, Hans van Bokhoven, Klas G. Wiman

, Huiqing Zhou, Daniel Aberdam, Isabelle Petit

Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1 ^MET

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Jinfeng Shen, Ellen H. van den Bogaard, Evelyn N. Kouwenhoven, Vladimir J. N. Bykov, Tuula Rinne, Qiang Zhang, Geuranne S. Tjabringa, Christian Gilissen, Simon J. van Heeringen, Joost Schalkwijk, Hans van Bokhoven, Klas G. Wiman

, Huiqing Zhou

APR-246/PRIMA-1 ^MET rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations

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2012 Harsha S. Madapura, Daniel Salamon, Klas G. Wiman

, Sonia Lain, George Klein, Eva Klein, Noémi Nagy

p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP

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Sören Lehmann, Vladimir J. N. Bykov, Dina Ali, Ove Andrén, Honar Cherif, Ulf Tidefelt, Bertil Uggla, Jeffrey Yachnin, Gunnar Juliusson, Ali Moshfegh, Christer Paul, Klas G. Wiman

, Per-Ola Andersson

Targeting p53 in Vivo: A First-in-Human Study With p53-Targeting Compound APR-246 in Refractory Hematologic Malignancies and Prostate Cancer

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A. Vilborg, C. Bersani, M. Wickström, L. Segerström, P. Kogner, K. G. Wiman

Wig-1, a novel regulator of N-Myc mRNA and N-Myc-driven tumor growth

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2011 G. Blandino, W. Deppert, P. Hainaut

, A. Levine, G. Lozano, M. Olivier, V. Rotter, K. Wiman

, M. Oren

Mutant p53 protein, master regulator of human malignancies: a report on the fifth Mutant p53 Workshop

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A. Vilborg, C. Bersani, M. T. Wilhelm

, K. G. Wiman

The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?

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2010 Salah Mahmoudi, Sofia Henriksson, Irene Weibrecht, Stephen Smith, Ola Söderberg, Staffan Strömblad

, Klas G. Wiman

, Marianne Farnebo

WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

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N. Rökaeus, J. Shen, I. Eckhardt, V. J. N. Bykov, K. G. Wiman

, M. T. Wilhelm

PRIMA-1MET/APR-246 targets mutant forms of p53 family members p63 and p73

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This paper is available in a repository.

Doriane A. Gouas, Claude Caron de Fromentel, Hong Shi, Agnès H. Hautefeuille, Sandra L. Ortiz Cuaran

, Pénélope C. Legros, Katarzyna J. Szymanska, Olivier Galy, Lars A. Egevad, Behnoush Abedi-Ardekani, Klas G. Wiman

, Olivier Hantz, Claude Caron de Fromentel, Isabelle A. Chemin, Pierre L. Hainaut

Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: Interaction with hepatitis B virus X protein

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Papers authored by Klas Wiman