Jean-Paul Blondeau

All papers authored by Jean-Paul Blondeau

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2020 Marianna Bufano

, Marion Laudette

, Jean-Paul Blondeau

, Frank Lezoualc’h

, Marianna Nalli

, Romano Silvestri

, Andrea Brancale

, Antonio Coluccia

Modeling Epac1 interactions with the allosteric inhibitor AM-001 by co-solvent molecular dynamics

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2019 Marion Bouvet, Jean-Paul Blondeau

, Frank Lezoualc’h

The Epac1 Protein: Pharmacological Modulators, Cardiac Signalosome and Pathophysiology

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Marion Laudette, Antonio Coluccia, Yannis Sainte-Marie, Andrea Solari, Loubina Fazal, Pierre Sicard, Romano Silvestri, Jeanne Mialet-Perez, Sandrine Pons, Bijan Ghaleh, Jean-Paul Blondeau

, Frank Lezoualc’h

Identification of a pharmacological inhibitor of Epac1 that protects the heart against acute and chronic models of cardiac stress

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2018 Stephen Boulton, Rajeevan Selvaratnam, Jean-Paul Blondeau

, Frank Lezoualc’h, Giuseppe Melacini

Mechanism of Selective Enzyme Inhibition through Uncompetitive Regulation of an Allosteric Agonist

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2014 Malik Bisserier, Jean-Paul Blondeau

, Frank Lezoualc'H

Epac proteins: specific ligands and role in cardiac remodelling.

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2013 Delphine Courilleau, Pascal Bouyssou, Rodolphe Fischmeister, Frank Lezoualc'H, Jean-Paul Blondeau

The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).

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2012 Delphine Courilleau, Malik Bisserier, Jean-Christophe Jullian, Alexandre Lucas, Pascal Bouyssou, Rodolphe Fischmeister, Jean-Paul Blondeau

, Frank Lezoualc'H

Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac.

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Maya Lévy-Bimbot, Geneviève Major, Delphine Courilleau, Jean-Paul Blondeau

, Yves Lévi

Tetrabromobisphenol-A disrupts thyroid hormone receptor alpha function in vitro: Use of fluorescence polarization to assay corepressor and coactivator peptide binding

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Matthieu Ruiz, Delphine Courilleau, Jean-Christophe Jullian, Dominique Fortin, Renée Ventura-Clapier, Jean-Paul Blondeau

, Anne Garnier

A Cardiac-Specific Robotized Cellular Assay Identified Families of Human Ligands as Inducers of PGC-1α Expression and Mitochondrial Biogenesis.

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2010 Mélanie Métrich, Anne-Coline Laurent, Magali Breckler, Nicolas Duquesnes, Isabelle Hmitou, Delphine Courillau, Jean-Paul Blondeau

, Bertrand Crozatier, Frank Lezoualc'h, Eric Morel

Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway

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2009 Nathalie Journiac, Sarah Jolly, Christopher Jarvis, Vanessa Gautheron, Monique Rogard, Alain Trembleau, Jean-Paul Blondeau

, Jean Mariani, Béatrice Vernet-Der Garabedian, Béatrice Vernet-Der Garabedian

The nuclear receptor RORα exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

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Mary-Line Jugan, Yves Levi, Jean-Paul Blondeau

Endocrine disruptors and thyroid hormone physiology

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M. L. Jugan, L. Oziol, M. Bimbot, V. Huteau, S. Tamisier-Karolak, J. P. Blondeau

, Y. Lévi

In vitro assessment of thyroid and estrogenic endocrine disruptors in wastewater treatment plants, rivers and drinking water supplies in the greater Paris area (France)

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2008 Nicolas Szabo-Fresnais, Jean-Paul Blondeau

, Martine Pomérance

Activation of the cAMP pathway synergistically increases IL-1-induced IL-6 gene expression in FRTL-5 thyroid cells: Involvement of AP-1 transcription factors

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2007 M. L. Jugan, M. Lévy-Bimbot, M. Pomérance, S. Tamisier-Karolak, J. P. Blondeau

, Y. Lévi

A new bioluminescent cellular assay to measure the transcriptional effects of chemicals that modulate the alpha-1 thyroid hormone receptor

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2006 M. Pomérance, J. Quillard, F. Chantoux, J. Young, J‐P-P. Blondeau

High-level expression, activation, and subcellular localization of p38-MAP kinase in thyroid neoplasms

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2005 C. Correze, J.-P. Blondeau

, M. Pomerance

p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells

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Martine Pomérance, Michaël Mockey, Jacques Young, Jeanine Quillard, Jean-Paul Blondeau

Expression, Hormonal Regulation, and Subcellular Localization of CCAAT/Enhancer-Binding Protein-β in Rat and Human Thyrocytes

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2003 Martine Pomerance, Daniel Carapau, Françoise Chantoux, Michaël Mockey, Claude Correze, Jacques Francon, Jean-Paul Blondeau

CCAAT/enhancer-binding protein-homologous protein expression and transcriptional activity are regulated by 3',5'-cyclic adenosine monophosphate in thyroid cells.

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2002 Jean-Paul Blondeau

Homologues of amino acid permeases: cloning and tissue expression of XAT1 and XAT2

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All papers authored by Jean-Paul Blondeau