Carl Webster - Dissemin

2019 Wendy A. Williams, John E. Linley, Clare A. Jones, Yoko Shibata, Arjan Snijder, James Button, Jon P. Hatcher, Ling Huang, Bruck Taddese, Peter Thornton, Darren J. Schofield, George Thom, Bojana Popovic, Bhupinder Dosanjh, Trevor Wilkinson and 7 other authors

Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain

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2018 Arsalan S. Haqqani, George Thom, Matthew Burrell, Christie E. Delaney, Eric Brunette, Ewa Baumann, Caroline Sodja, Anna Jezierski, Carl Webster

, Danica B. Stanimirovic

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity

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George Thom, Mei Tian, Jon P. Hatcher, Natalia Rodrigo, Matthew Burrell, Ian Gurrell, Timothy Z. Vitalis, Thomas Abraham, Wilfred A. Jefferies, Carl I. Webster

, Reinhard Gabathuler

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model

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George Thom, Matthew Burrell, Arsalan S. Haqqani, Alvaro Yogi, Etienne Lessard, Eric Brunette, Christie Delaney, Ewa Baumann, Deborah Callaghan, Natalia Rodrigo, Carl I. Webster

, Danica B. Stanimirovic

Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26

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2017 George Thom, Jon Hatcher, Arron Hearn, Judy Paterson, Natalia Rodrigo, Arthur Beljean, Ian Gurrell, Carl Webster

Isolation of blood-brain barrier-crossing antibodies from a phage display library by competitive elution and their ability to penetrate the central nervous system

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This paper is available in a repository.

Louise S. C. Nicol, Peter Thornton, Jon P. Hatcher, Colin P. Glover, Carl I. Webster

, Matthew Burrell, Kessia Hammett, Clare A. Jones, Matthew A. Sleeman, Andrew Billinton, Iain Chessell

Central inhibition of granulocyte-macrophage colony-stimulating factor is analgesic in experimental neuropathic pain:

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John Greenwood, Margareta Hammarlund-Udenaes, Hazel C. Jones, Alan W. Stitt, Roosmarijn E. Vandenbroucke, Ignacio A. Romero, Matthew Campbell, Gert Fricker, Birger Brodin, Heiko Manninga, Pieter J. Gaillard, Markus Schwaninger, Carl Webster

, Krzysztof B. Wicher, Michel Khrestchatisky

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017

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Joe K. Chouhan, Susan B. Fowler, Carl I. Webster

, Jessica L. Teeling

The ME7 prion model of neurodegeneration as a tool to understand and target neuroinflammation in Alzheimer’s disease

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2016 Carl I. Webster

, Jon Hatcher, Matthew Burrell, George Thom, Peter Thornton, Ian Gurrell, Iain Chessell

Enhanced delivery of IL-1 receptor antagonist to the central nervous system as a novel anti–transferrin receptor-IL-1RA fusion reverses neuropathic mechanical hypersensitivity:

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Matthew Burrell, Simon J. Henderson, Anna Ravnefjord, Fritz Schweikart, Susan B. Fowler, Susanne Witt, Kenny M. Hansson, Carl I. Webster

Neprilysin Inhibits Coagulation through Proteolytic Inactivation of Fibrinogen

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Judy Paterson, Carl I. Webster

Exploiting transferrin receptor for delivering drugs across the blood-brain barrier

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Carl I. Webster

, Nadia Caram-Salas, Arsalan S. Haqqani, George Thom, Lee Brown, Kerry Rennie, Alvaro Yogi, Willard Costain, Eric Brunette, Danica B. Stanimirovic

Brain penetration, target engagement, and disposition of the blood-brain barrier-crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1

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Carl I. Webster

, Christine J. Bryson, Edward A. Cloake, Tim D. Jones, Mark J. Austin, Anette C. Karle, Sebastian Spindeldreher, David C. Lowe, Matthew P. Baker

A comparison of the ability of the human IgG1 allotypes G1m3 and G1m1,17 to stimulate T-cell responses from allotype matched and mismatched donors

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2015 Carl I. Webster

, Danica B. Stanimirovic

A gateway to the brain: shuttles for brain delivery of macromolecules

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All papers authored by Carl Webster