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All papers authored by Xavier Grana

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2023 Marissa L. Calbert

ORCID

, Gurushankar Chandramouly

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, Clare M. Adams

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, Magali Saez-Ayala

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, Mrityunjay Tyagi

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, V. S. S. Abhinav Ayyadevara

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, John J. Krais

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, Jessica Atkins

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, Monika M. Toma

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, Stéphane Betzi

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, Andrew S. Boghossian

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, Matthew G. Rees

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and 13 other authors

4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress

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2021 Holly Fowle, Ziran Zhao, Qifang Xu, Jason S. Wasserman, Xinru Wang

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, Mary Adeyemi, Felicity Feiser, Alison N. Kurimchak, Diba Atar, Brennan C. McEwan, Arminja N. Kettenbach

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, Rebecca Page, Wolfgang Peti, Roland L. Dunbrack, Xavier Graña

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PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107

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2020 Ziran Zhao, Holly Fowle, Henkel Valentine, Zemin Liu, Yinfei Tan, Jianming Pei, Simone Badal

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, Joseph R. Testa, Xavier Graña

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Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase

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2019 Ziran Zhao, Alison Kurimchak, Anna S. Nikonova, Felicity Feiser, Jason S. Wasserman, Holly Fowle, Tinsa Varughese, Megan Connors, Katherine Johnson, Petr Makhov, Cecilia Lindskog, Vladimir M. Kolenko, Erica A. Golemis

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, James S. Duncan, Xavier Graña

ORCID

PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization

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Battuya Bayarmagnai, Louisiane Perrin, Kamyar Esmaeili Pourfarhangi, Xavier Graña

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, Bojana Gligorijevic

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Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle

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Holly Fowle, Ziran Zhao, Xavier Graña

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PP2A holoenzymes, substrate specificity driving cellular functions and deregulation in cancer

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2018 Hanghang Zhang, Somnath Pandey, Meghan Travers, Hongxing Sun, George Morton, Jozef Madzo, Woonbok Chung, Jittasak Khowsathit, Oscar Perez-Leal, Carlos A. Barrero, Carmen Merali, Yasuyuki Okamoto, Takahiro Sato, Joshua Pan, Judit Garriga and 18 other authors

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

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2014 Alison Kurimchak, Xavier Graña

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PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues

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Judit Garriga, Xavier Graña

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CDK9 inhibition strategy defines distinct sets of target genes

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2013 Alison Kurimchak, Dale S. Haines, Judit Garriga, Shufang Wu, Francesco De Luca, Michael J. Sweredoski, Raymond J. Deshaies

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, Sonja Hess, Xavier Gra\~na, Xavier Graña

ORCID

Activation of p107 by Fibroblast Growth Factor, Which Is Essential for Chondrocyte Cell Cycle Exit, Is Mediated by the Protein Phosphatase 2A/B55α Holoenzyme

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Thomas Cherrier, Valentin Le Douce, Valentin Le Douce, Sebastian Eilebrecht, Raphael Riclet, Celine Marban, Franck Dequiedt, Yannick Goumon, Jean-Christophe Paillart, Mathias Mericskay, Ara Parlakian, Pedro Bausero, Wasim Abbas, Georges Herbein, Siavash K. Kurdistani and 7 other authors

CTIP2 is a negative regulator of P-TEFb.

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2012 Xavier Graña

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Monographs Editor

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Xavier Grana

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Introduction: Current Themes on Cell Cycle and Cancer

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Alison Kurimchak, Xavier Graña

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PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer

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Alison Kurimchak, Xavier Graña

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PP2A holoenzymes negatively and positively regulate cell cycle progression by dephosphorylating pocket proteins and multiple CDK substrates

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Havva Keskin, Judit Garriga, Daphne Georlette, Xavier Graña

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Complex effects of flavopiridol on the expression of primary response genes

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2010 Girish Jayadeva, Alison Kurimchak, Judit Garriga, Elena Sotillo, Anthony J. Davis, Dale S. Haines, Marc Mumby, Xavier Graña

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B55α PP2A Holoenzymes Modulate the Phosphorylation Status of the Retinoblastoma-related Protein p107 and Its Activation*

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Dayana B. Rivadeneira, Christopher N. Mayhew, Chellappagounder Thangavel, Elena Sotillo, Christopher A. Reed, Xavier Graña

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, Erik S. Knudsen

Proliferative Suppression by CDK4/6 Inhibition: Complex Function of the Retinoblastoma Pathway in Liver Tissue and Hepatoma Cells

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Haritha K. D. L. Reddy, Xavier Graña

ORCID

, Danny N. Dhanasekaran, Judith Litvin, E. Premkumar Reddy

Requirement of Cdk4 for v-Ha-ras–Induced Breast Tumorigenesis and Activation of the v-ras–Induced Senescence Program by the R24C Mutation

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2009 Judit Garriga, Hongbo Xie

ORCID

, Zoran Obradovic, Xavier Graña

ORCID

Selective control of gene expression by CDK9 in human cells

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