Christina Yap - Dissemin

Papers authored by Christina Yap

This paper is made freely available by the publisher.

2021 Rebecca B. Silva

, Christina Yap

Would the Recommended Dose Have Been Different Using Novel Dose-Finding Designs? Comparing Dose-Finding Designs in Published Trials

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Nina Wilson, Katie Biggs, Sarah Bowden, Julia Brown, Munyaradzi Dimairo, Laura Flight, Jamie Hall, Anna Hockaday, Thomas Jaki, Rachel Lowe, Caroline Murphy, Philip Pallmann, Mark A. Pilling, Claire Snowdon, Matthew R. Sydes and 7 other authors

Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

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Julia Lai‐Kwon

, Zhulin Yin

, Anna Minchom, Christina Yap

Trends in patient‐reported outcome use in early phase dose‐finding oncology trials – an analysis of ClinicalTrials.gov

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Crescens Tiu, Liam Welsh, Timothy Jones, Anna Zachariou, Toby Prout, Alison Turner, Rob Daly, Nina Tunariu, Ruth Riisnaes, Bora Gurel, Mateus Crespo

, Suzanne Carreira, Igor Vivanco, Johann deBono, Ben Jenkins and 4 other authors

Preliminary evidence of antitumour activity of Ipatasertib (Ipat) and Atezolizumab (ATZ) in glioblastoma patients (pts) with PTEN loss from the Phase 1 Ice-CAP trial (NCT03673787)

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Abhijit Pal

, Sarah Stapleton

, Christina Yap

, Julia Lai-Kwon, Robert Daly, Dimitrios Magkos, Bindumalini Rao Baikady, Anna Minchom, Udai Banerji, Johann De Bono, Deme Karikios, Frances Boyle, Juanita Lopez

Study protocol for a randomised controlled trial of enhanced informed consent compared to standard informed consent to improve patient understanding of early phase oncology clinical trials (CONSENT)

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This paper was not found in any repository, but could be made available legally by the author.

S. Banerjee

, R. Grochot, R. Shinde, J. Lima, M. Krebs, R. Rahman, M. Little, N. Tunariu, A. Curcean, H. Badham, M. Mahmud, A. Turner, M. Parmar, C. Yap

, A. Minchom and 3 other authors

725MO Phase I study of the combination of the dual RAF/MEK inhibitor VS-6766 and the FAK inhibitor defactinib: Results of efficacy in low grade serous ovarian cancer

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P. Bono, A. Minchom, S. Shetty, Y. T. Ma, R. Cruz, M. J. A. de Jonge, C. Yap

, A. Pasanen, T. Skytta, S. M. E. Iivanainen, L. Verlingue, P. Jaakkola, M. J. de Miguel, S. Arora, D. Graham and 6 other authors

LBA38 Bexmarilimab, a novel macrophage re-programmer shows promising anti-tumour activity in phase I/II trial in several last line solid tumour types

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J. E. Lai-Kwon, A. Vanderbeek, A. Minchom, C. Yap

520MO Using patient-reported outcomes (PROs) in dose-finding oncology trials (DFOT): Results from a global stakeholder survey and the National Cancer Research Institute (NCRI) Consumer Forum

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M. Cole, C. Yap

, C. Buckley, W. F. Ng, I. McInnes, A. Filer, S. Siebert, A. Pratt

, J. D. Isaacs, D. D. Stocken

TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

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Crescens Tiu, Andrea Biondo, Liam C. Welsh, Timothy L. Jones, Anna Zachariou, Toby Prout, Alison J. Turner, Robert Daly, Igor Vivanco, Christina Yap

, Ben Jenkins, Mateus Crespo, Ruth Riisnaes, Suzanne Carreira, Bora Gurel and 5 other authors

Abstract CT120: Results of the glioblastoma multiforme (GBM) cohort of phase 1 trial Ice-CAP (NCT03673787): Preliminary evidence of antitumour activity of Ipatasertib (Ipa) and Atezolizumab (A) in patients (pts) with PTEN loss

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Matthew G. Krebs, Rajiv Shinde, Rozana Abdul Rahman, Rafael Grochot, Martin Little, Jenny King, Joseph Kitchin, Mona Parmar, Alison Turner, Muneeb Mahmud, Christina Yap

, Nina Tunariu, Juanita Lopez, Johann S. De Bono, Udai Banerji and 1 other authors

Abstract CT019: A phase I trial of the combination of the dual RAF-MEK inhibitor VS-6766 and the FAK inhibitor defactinib: Evaluation of efficacy in KRAS mutated NSCLC

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G. P. Collins, S. Booth, L. R. Cherrill, D. Slade, C. Morland, L. Hopkins, E. Nagy, K. Linton, C. P. Fox, D. Lewis, A. Davies, G. Turner, G. Rees, C. Yap

, K. Cwynarski

Romidepsin and Carfilzomib in Relapsed / Refractory Peripheral T‐cell Lymphoma With Assessment of H23b as a Predictive Biomarker – The Uk Ncri Seamless Phase 1/2 Romicar Trial

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Stefan Siebert, Deborah D. Stocken, Christina Yap

, Michael Cole, Arthur G. Pratt

, Muddassir Shaikh, Stephen Kelly, Jenn Walker, Amy Cranston, Miranda Morton, Sheelagh Frame, Wan-Fai Ng, Christopher D. Buckley, Iain B. McInnes, Andrew Filer and 1 other authors

Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial

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J. E. Lai-Kwon, A. Vanderbeek, A. Minchom, C. Yap

42P Using patient-reported outcomes (PROs) in phase I/II dose-finding oncology trials (DPOT): A global survey

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Ethan Basch

, Christina Yap

Patient-reported Outcomes for Tolerability Assessment in Phase I Cancer Clinical Trials

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Khobe Chandran, Maria Dolores Fenor de la Maza, Jan Rekowski, Irene Shui, Bora Gurel, Pasquale Rescigno, Emily Cross, Suzanne Carreira, Wei Yuan, Ines Figueiredo, Ana Ferreira, Mateus Crespo, Susana Miranda, Claudia Bertan, Veronica Gil and 5 other authors

Putative biomarkers of response to anti-PD-1 therapy in metastatic castration-resistant prostate cancer (mCRPC).

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Julia Lai-Kwon, Alyssa Vanderbeek, Anna Minchom, Christina Yap

Using Patient-Reported Outcomes (PROs) in Early-Phase Dose-finding Oncology Trials (EDOT): a global survey

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Matthew G. Krebs, Rajiv Shinde, Rozana Abdul Rahman, Rafael Grochot, Martin Little, Jenny King, Joseph Kitchin, Mona Parmar, Alison Turner, Muneeb Mahmud, Christina Yap

, Nina Tunariu, Juanita Lopez, Johann S. De Bono, Udai Banerji and 1 other authors

A phase I trial of the combination of the dual RAF-MEK inhibitor VS-6766 and the FAK inhibitor defactinib: Evaluation of efficacy in KRAS mutated NSCLC

Upload

Crescens Tiu, Andrea Biondo, Liam C. Welsh, Timothy L. Jones, Anna Zachariou, Toby Prout, Alison J. Turner, Robert Daly, Igor Vivanco, Christina Yap

, Ben Jenkins, Mateus Crespo, Ruth Riisnaes, Suzanne Carreira, Bora Gurel and 5 other authors

Results of the glioblastoma multiforme (GBM) cohort of phase 1 trial Ice-CAP (NCT03673787): Preliminary evidence of antitumour activity of Ipatasertib (Ipa) and Atezolizumab (A) in patients (pts) with PTEN loss

Upload

2020 Mark W. Drummond, Charlotte Gaskell, Claire Harrison, Adam J. Mead, Christina Yap

, Aimee E. Jackson, Jennifer Byrne, Fiona J. Clark, Srinivasan Narayanan, David Bowen, Tim C. P. Somervaille, Emma Gudgin, Dragana Milojkovic, Rachel S. Fletcher, Charlotte K. Brierley and 1 other authors

Phazar: A Phase Ib Study to Assess the Safety and Tolerability of Ruxolitinib in Combination with Azacitidine in Advanced Phase Myeloproliferative Neoplasms (MPN), Including Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukaemia (AML) Arising from MPN [ISRCTN16783472]

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Papers authored by Christina Yap