Daniel Leclerc - Dissemin

All papers authored by Daniel Leclerc

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2021 Daniel Leclerc

, Jaroslav Jelinek

, Karen E. Christensen

, Jean-Pierre J. Issa, Rima Rozen

High folic acid intake increases methylation-dependent expression of Lsr and dysregulates hepatic cholesterol homeostasis

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2020 Marta Cosín-Tomás

, Yan Luan, Daniel Leclerc

, Olga V. Malysheva, Nidia Lauzon, Renata H. Bahous, Karen E. Christensen

, Marie A. Caudill

, Rima Rozen

Moderate Folic Acid Supplementation in Pregnant Mice Results in Behavioral Alterations in Offspring with Sex-Specific Changes in Methyl Metabolism

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2018 Daniel Leclerc

, Karen E. Christensen, Olivia Cauvi, Ethan Yang, Frédéric Fournelle, Renata H. Bahous, Olga V. Malysheva, Liyuan Deng, Qing Wu, Zili Zhou, Zu-Hua Gao, Pierre Chaurand, Marie A. Caudill, Rima Rozen

Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver

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Renata H. Bahous, Marta Cosín-Tomás

, Liyuan Deng, Daniel Leclerc

, Olga Malysheva, Ming-Kai Ho, Mercè Pallàs, Perla Kaliman, Barry J. Bedell, Marie A. Caudill, Rima Rozen

Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency

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Mahmoud Aarabi, Karen E. Christensen, Donovan Chan, Daniel Leclerc

, Mylène Landry, Lundi Ly, Rima Rozen, Jacquetta Trasler

Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation

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2017 Daniel Leclerc

, Rima Rozen

Genetic or nutritional disturbances in folate-related pathways and epigenetic interactions

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D. Leclerc

, D. N. T. Pham, N. Lévesque, M. Truongcao, W. D. Foulkes, C. Sapienza, R. Rozen

Oncogenic role of PDK4 in human colon cancer cells

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2016 Nancy Lévesque, Daniel Leclerc

, Tenzin Gayden, Anthoula Lazaris, Nicolas De Jay, Stephanie Petrillo, Peter Metrakos, Nada Jabado, Rima Rozen

Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5′-end methylation

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2014 Daniel Leclerc

, Kurt Dejgaard, Alexander Mazur, Liyuan Deng, Qing Wu, Tommy Nilsson, Rima Rozen

Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency

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Alexander Lossos, Omri Teltsh, Tsipi Milman, Vardiella Meiner, Rima Rozen, Daniel Leclerc

, Bernd C. Schwahn, Natalya Karp, David S. Rosenblatt, David Watkins, Avraham Shaag, Stanley H. Korman, Samuel N. Heyman, Aya Gal, J. P. Newman and 3 other authors

Severe Methylenetetrahydrofolate Reductase Deficiency

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2013 Daniel Leclerc

, Nancy Levesque, Yuanhang Cao, Liyuan Deng, Qing Wu, Jasmine Powell, Carmen Sapienza, Rima Rozen

Genes with Aberrant Expression in Murine Preneoplastic Intestine Show Epigenetic and Expression Changes in Normal Mucosa of Colon Cancer Patients

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Diep Ngoc Thi Pham, Daniel Leclerc

, Nancy Lévesque, Liyuan Deng, Rima Rozen

β,β-Carotene 15,15′-monooxygenase and its substrate β-carotene modulate migration and invasion in colorectal carcinoma cells

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2012 Daniel Leclerc

, Yuanhang Cao, Liyuan Deng, Leonie G. Mikael, Qing Wu, Rima Rozen

Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

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Nafisa M. Jadavji, Liyuan Deng, Daniel Leclerc

, Olga Malysheva, Barry J. Bedell, Marie A. Caudill, Rima Rozen

Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus

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2011 Erin Knock, Liyuan Deng, Natalia Krupenko, Ryan D. Mohan, Qing Wu, Daniel Leclerc

, Sapna Gupta, C. Lee Elmore, Warren Kruger, Marc Tini, Rima Rozen

Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair

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Laura Pickell, Qing Wu, Xiao-Ling Wang, Daniel Leclerc

, Hana Friedman, Alan C. Peterson, Rima Rozen

Targeted insertion of two Mthfr promoters in mice reveals temporal- and tissue-specific regulation

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2008 Marc Roy, Daniel Leclerc

, Qing Wu, Sapna Gupta, Warren D. Kruger, Rima Rozen

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Download from www.ncbi.nlm.nih.gov

Basak Celtikci, Daniel Leclerc

, Andrea K. Lawrance, Liyuan Deng, Hana C. Friedman, Natalia I. Krupenko, Sergey A. Krupenko, Stepan Melnyk, S. Jill James, Alan C. Peterson, Rima Rozen

Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice

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2007 Daniel Leclerc

, Rima Rozen

Endoplasmic Reticulum Stress Increases the Expression of Methylenetetrahydrofolate Reductase through the IRE1 Transducer

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Cande V. Ananth, Denise A. Elsasser, Wendy L. Kinzler, Morgan R. Peltier, Darios Getahun, Daniel Leclerc

, Rima R. Rozen

Polymorphisms in Methionine Synthase Reductase and Betaine-Homocysteine S-Methyltransferase Genes: Risk of Placental Abruption

Download from www.ncbi.nlm.nih.gov

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All papers authored by Daniel Leclerc