Edwige Lorthiois - Dissemin

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All papers authored by Edwige Lorthiois

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2022 Edwige Lorthiois

ORCID

, Marc Gerspacher, Kim S. Beyer

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, Andrea Vaupel

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, Catherine Leblanc, Rowan Stringer

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, Andreas Weiss

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, Rainer Wilcken

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, Daniel A. Guthy

ORCID

, Andreas Lingel

ORCID

, Claudio Bomio-Confaglia

ORCID

, Rainer Machauer

ORCID

, Pascal Rigollier, Johannes Ottl

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, Dorothee Arz and 16 other authors

JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS^G12C for the Treatment of Solid Tumors

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This paper was not found in any repository, but could be made available legally by the author.

2020 Edwige Lorthiois

ORCID

ORCID

, David Barnes-Seeman, Eva Altmann

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, Ulrich Hassiepen, Gordon Turner, Rohit Duvadie, Viktor Hornak, Rajeshri G. Karki

ORCID

, Nikolaus Schiering, Wilhelm A. Weihofen, Francesca Perruccio, Amy Calhoun, Tanzina Fazal, Darija Dedic and 40 other authors

Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2019 Rajeshri G. Karki

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, James Powers, Nello Mainolfi, Karen Anderson, David B. Belanger, Donglei Liu, Nan Ji, Keith Jendza, Christine F. Gelin, Aengus Mac Sweeney, Catherine Solovay, Omar Delgado, Maura Crowley, Sha-Mei Liao, Upendra A. Argikar

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and 13 other authors

Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway

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2018 Anna Vulpetti

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, Nils Ostermann, Stefan Randl, Taeyoung Yoon, Aengus Mac Sweeney, Frederic Cumin, Edwige Lorthiois

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, Simon Rüdisser, Paul Erbel, Jürgen Maibaum

Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D

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This paper was not found in any repository, but could be made available legally by the author.

2017 Edwige Lorthiois

ORCID

, Karen Anderson, Anna Vulpetti

ORCID

, Olivier Rogel, Frederic Cumin, Nils Ostermann, Stefan Steinbacher, Aengus Mac Sweeney, Omar Delgado, Sha-Mei Liao, Stefan Randl, Simon Rüdisser, Solene Dussauge, Kamal Fettis, Laurence Kieffer and 11 other authors

Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo

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