Philippe Clezardin
www.lyos.fr
0000-0003-0149-4463
INSERM
270 papers found
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Ne-10790, a Phosphonocarboxylate Analogue of the Bisphosphonate Risedronate, Exhibits Direct Antitumor Activity in in Vivo
Use of bisphosphonate analogs of risedronate to elucidate antitumor mechanisms of bisphosphonates in vivo.
Angiostatin Inhibits Bone Metastasis Formation in Nude Mice through a Direct Anti-osteoclastic Activity
SiRNA-mediated Inhibition of Vascular Endothelial Growth Factor Severely Limits Tumor Resistance to Antiangiogenic Thrombospondin-1 and Slows Tumor Vascularization and Growth
Androgens repress the expression of thrombospondin-1, an inhibitor of angiogenesis, in the rat prostate and in hormone-responsive human prostate cancer
In Vitro and In Vivo Antitumor Effects of Bisphosphonates
Bisphosphonates and bone metastases of solid tumors: therapeutic interest despite its anti-resorptive properties
Mechanisms of Bisphosphonate Effects on Osteoclasts, Tumor Cell Growth, and Metastasis:
Bisphosphonates inhibit angiogenesis in vitro and testosterone-stimulated vascular regrowth in the ventral prostate in castrated rats
Integrin αvβ3 expression confers on tumor cells a greater propensity to metastasize to bone
Effects of bisphosphonates zoledronic acid and risedronate on the growth of a human breast carcinoma cell line in vivo
Integrin alpha v beta 3 plays an essential role in the homing of tumor cells in bone.
Early Detection of Bone Metastases in a Murine Model Using Fluorescent Human Breast Cancer Cells: Application to the Use of the Bisphosphonate Zoledronic Acid in the Treatment of Osteolytic Lesions
In vivo mechanisms by which tumors producing thrombospondin 1 bypass its inhibitory effects
Platelet-Osteosarcoma Cell Interaction is Mediated Through a Specific Fibrinogen-Binding Sequence Located Within the N-Terminal Domain of Thrombospondin 1
Mechanisms of action of bisphosphonates on tumor cells and prospects for use in the treatment of malignant osteolysis
Bone metastasis
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases
Decorin inhibits cell migration through a process requiring its glycosaminoglycan side chain
Additive antitumor activities of taxoids in combination with the bisphosphonate ibandronate against invasion and adhesion of human breast carcinoma cells to bone
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