Samuel Kohtala - Dissemin

All papers authored by Samuel Kohtala

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2023 Okko Alitalo, Gemma González-Hernández, Marko Rosenholm

, Piia Kohtala, Nobuaki Matsui, Heidi Kaastrup Müller, Wiebke Theilmann, Anders Klein, Olli Kärkkäinen, Stanislav Rozov, Tomi Rantamäki, Samuel Kohtala

Linking Hypothermia and Altered Metabolism with TrkB Activation

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A. Ahtiainen

, I. Annala

, M. Rosenholm

, S. Kohtala

, J. Hyttinen, J. M. A. Tanskanen, T. Rantamäki

Ketamine reduces electrophysiological network activity in cortical neuron cultures already at sub-micromolar concentrations – Impact on TrkB-ERK1/2 signaling

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2021 Okko Alitalo, Samuel Kohtala

, Marko Rosenholm, Piia Kohtala, Roosa Saarreharju, Nobuaki Matsui, Gemma Gonzalez Hernandez, Heidi Kaastrup Müller, Wiebke Theilmann, Mirkka Sarparanta, Anders Klein, Olli Kärkkäinen, Stanislav Rozov, Tomi Rantamäki

Physiological basis underlying antidepressant-induced activation of TrkB receptors

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Okko Alitalo

, Roosa Saarreharju

, Ioline D. Henter

, Carlos A. Zarate, Samuel Kohtala

, Tomi Rantamäki

A wake-up call: Sleep physiology and related translational discrepancies in studies of rapid-acting antidepressants

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This paper is made freely available by the publisher.

Samuel Kohtala

, Tomi Rantamäki

Rapid‐acting antidepressants and the regulation of TrkB neurotrophic signalling—Insights from ketamine, nitrous oxide, seizures and anaesthesia

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Samuel Kohtala

Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms

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2020 S. Kohtala

, O. Alitalo, M. Rosenholm

, S. Rozov, T. Rantamäki

Time is of the essence: Coupling sleep-wake and circadian neurobiology to the antidepressant effects of ketamine

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Okko Alitalo, Roosa Saarreharju, Carlos A. Zarate, Samuel Kohtala

, Tomi Rantamäki

A wake-up call - revealing the oversight of sleep physiology and related translational discrepancies in studies of rapid-acting antidepressants

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Tomi Rantamäki, Samuel Kohtala

Encoding, Consolidation, and Renormalization in Depression: Synaptic Homeostasis, Plasticity, and Sleep Integrate Rapid Antidepressant Effects

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2019 Samuel Kohtala

, Wiebke Theilmann, Marko Rosenholm

, Heidi K. Müller, Paula Kiuru, Gregers Wegener

, Jari Yli-Kauhaluoma

, Tomi Rantamäki

Ketamine-induced regulation of TrkB-GSK3β signaling is accompanied by slow EEG oscillations and sedation but is independent of hydroxynorketamine metabolites

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Samuel Kohtala

, Tomi Rantamäki

Commentary: Commonly Used Anesthesia/Euthanasia Methods for Brain Collection Differentially Impact MAPK Activity in Male and Female C57BL/6 Mice

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Samuel Kohtala

Rapid-acting antidepressants

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S. Kohtala

, O. Kärkkäinen, T. Rantamäki

P.1.17 Brain metabolome during anesthesia – similarities and differences between post-ictal state

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2018 Sakari Leino, Samuel Kohtala

, Tomi Rantamäki, Sini K. Koski, Saara Rannanpää, Outi Salminen

Dyskinesia and brain-derived neurotrophic factor levels after long-term levodopa and nicotinic receptor agonist treatments in female mice with near-total unilateral dopaminergic denervation

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Samuel Kohtala

, Wiebke Theilmann, Marko Rosenholm

, Leena Penna, Gulsum Karabulut, Salla Uusitalo, Kaija Järventausta, Arvi Yli-Hankala, Ipek Yalcin, Nobuaki Matsui, Henna-Kaisa Wigren, Tomi Rantamäki

Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

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Samuel Kohtala

, Wiebke Theilmann, Marko Rosenholm

, Paula Kiuru

, Salla Uusitalo, Kaija Järventausta, Arvi Yli-Hankala

, Jari Yli-Kauhaluoma

, Henna-Kaisa Wigren, Tomi Rantamäki

Putative rapid-acting antidepressant nitrous oxide ("laughing gas") evokes rebound emergence of slow EEG oscillations during which TrkB signaling is induced

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Samuel Kohtala

, Kaija Järventausta, Tomi Pentti Johannes Rantamäki

Neurobiologiset ilmiöt nopean masennuslääkevasteen taustalla

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Samuel Kohtala

Ilokaasu auttoi selvittämään masennuksen tehohoitojen vaikutusmekanismeja

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2017 Hanna Antila, Maria Ryazantseva, Dina Popova, Pia Sipilä, Ramon Guirado

, Samuel Kohtala

, Ipek Yalcin, Jesse Lindholm, Liisa Vesa, Vinicius Sato, Joshua Cordeira, Henri Autio, Mikhail Kislin, Sâmia Joca, Maribel Rios and 6 other authors

Isoflurane produces antidepressant effects and induces TrkB signaling in rodents

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Juuso V. Leikas, Samuel Kohtala

, Wiebke Theilmann, Aaro J. Jalkanen, Markus M. Forsberg, Tomi Rantamäki

Brief isoflurane anesthesia regulates striatal AKT-GSK3β signaling and ameliorates motor deficits in a rat model of early-stage Parkinson′s disease

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All papers authored by Samuel Kohtala