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All papers authored by Patrick Shea

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2022 Ian R. White, Sarah E. Kleinstein

ORCID

, Christophe Praet, Chris Chamberlain, Duncan McHale, Jessica M. Maia, Pingxing Xie, David B. Goldstein, Thomas J. Urban, Patrick R. Shea

ORCID

A genome-wide screen for variants influencing certolizumab pegol response in a moderate to severe rheumatoid arthritis population

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2018 Julia Wattacheril

ORCID

, Patrick R. Shea

ORCID

, Saeed Mohammad, Cynthia Behling, Vimla Aggarwal, Laura A. Wilson, Katherine P. Yates, Joy Ito, Mark Fishbein, Nicholas Stong, Joel E. Lavine, David B. Goldstein

Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson Disease

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Maureen P. Martin, Vivek Naranbhai

ORCID

, Patrick R. Shea

ORCID

, Ying Qi, Veron Ramsuran

ORCID

, Nicolas Vince

ORCID

, Xiaojiang Gao, Rasmi Thomas, Zabrina L. Brumme, Jonathan M. Carlson, Steven M. Wolinsky, James J. Goedert, Bruce D. Walker

ORCID

, Florencia P. Segal, Steven G. Deeks

ORCID

and 17 other authors

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

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Sarah E. Kleinstein, Patrick R. Shea

ORCID

, Luisa M. Stamm, Mark Sulkowski, David B. Goldstein, Susanna Naggie

Association of CYP2B6 Single-Nucleotide Polymorphisms Altering Efavirenz Metabolism With Hepatitis C Virus (HCV) Treatment Relapse Among Human Immunodeficiency Virus/HCV–Coinfected African Americans Receiving Ledipasvir/Sofosbuvir in the ION-4 Trial

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Sarah E. Kleinstein, Patrick R. Shea

ORCID

, Andrew S. Allen, David M. Koelle

ORCID

, Anna Wald, David B. Goldstein

Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2)

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2017 Paul J. McLaren

ORCID

, Sara L. Pulit, Deepti Gurdasani

ORCID

, Istvan Bartha, Patrick R. Shea

ORCID

, Cristina Pomilla, Namrata Gupta, Effrossyni Gkrania-Klotsas

ORCID

, Elizabeth H. Young, Norbert Bannert, Julia Del Amo, Julia Del Amo, M. John Gill

ORCID

, M. John Gill, Jill Gilmour and 15 other authors

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control

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Razan Abujaber, Patrick R. Shea

ORCID

, Paul J. McLaren, Shabir Lakhi, Jill Gilmour, Susan Allen, Jacques Fellay, Edward J. Hollox

No Evidence for Association of β-Defensin Genomic Copy Number with HIV Susceptibility, HIV Load during Clinical Latency, or Progression to AIDS

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2015 Paul J. McLaren

ORCID

, Cédric Coulonges, István Bartha

ORCID

, Tobias L. Lenz, Aaron J. Deutsch

ORCID

, Arman Bashirova, Susan Buchbinder, Mary N. Carrington, Andrea Cossarizza, Judith Dalmau, Andrea De Luca, James J. Goedert, Deepti Gurdasani

ORCID

, David W. Haas, Joshua T. Herbeck and 26 other authors

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

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2014 J. M. Mccarthy, P. R. Shea

ORCID

, D. B. Goldstein, A. S. Allen

Testing for risk and protective trends in genetic analyses of HIV acquisition

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2013 F. Balloux, Paul J. McLaren, Cédric Coulonges equal Contributor, Cédric Coulonges, Stephan Ripke, Leonard van den Berg, Stephen J. O. Brien, Susan Buchbinder, Mary Carrington, Andrea Cossarizza, Judith Dalmau, Steven G. Deeks, Leonard Den Berg, Olivier Delaneau, Andrea De Luca and 41 other authors

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

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Patrick R. Shea

ORCID

, Kevin V. Shianna, Mary Carrington, David B. Goldstein

Host Genetics of HIV Acquisition and Viral Control

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2012 Nahuel Fittipaldi, Stephen B. Beres

ORCID

, Randall J. Olsen, Vivek Kapur, Patrick R. Shea

ORCID

, M. Ebru Watkins, M. Ebru Watkins, Concepcion C. Cantu, Daniel R. Laucirica, Leslie Jenkins, Anthony R. Flores, Marguerite Lovgren, Carmen Ardanuy, Josefina Liñares, Donald E. Low and 2 other authors

Full-Genome Dissection of an Epidemic of Severe Invasive Disease Caused by a Hypervirulent, Recently Emerged Clone of Group A Streptococcus

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Randall J. Olsen, Daniel R. Laucirica, Melanie Ebru Watkins, M. Ebru Watkins, Marsha L. Feske, Jesus R. Garcia-Bustillos, Chau Vu, Concepcion Cantu, Samuel A. Shelburne, Nahuel Fittipaldi, Muthiah Kumaraswami, Patrick R. Shea

ORCID

, Anthony R. Flores, Stephen B. Beres, Maguerite Lovgren and 5 other authors

Polymorphisms in Regulator of Protease B (RopB) Alter Disease Phenotype and Strain Virulence of Serotype M3 Group A Streptococcus

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2011 Patrick R. Shea

ORCID

, Amy L. Ewbank, Javier H. Gonzalez-Lugo, Alexandro J. Martagon-Rosado, Juan C. Martinez-Gutierrez, Hina A. Rehman, Monica Serrano-Gonzalez, Nahuel Fittipaldi, Stephen B. Beres

ORCID

, Anthony R. Flores, Donald E. Low, Barbara M. Willey, James M. Musser

Group A Streptococcus emm Gene Types in Pharyngeal Isolates, Ontario, Canada, 2002–2010

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Ronan K. Carroll, Samuel A. Shelburne, Randall J. Olsen, Bryce Suber, Pranoti Sahasrabhojane, Muthiah Kumaraswami, Stephen B. Beres

ORCID

, Patrick R. Shea

ORCID

, Anthony R. Flores, James M. Musser

Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice

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Patrick R. Shea

ORCID

, Stephen B. Beres

ORCID

, Anthony R. Flores, Amy L. Ewbank, Javier H. Gonzalez-Lugo, Alexandro J. Martagon-Rosado, Juan C. Martinez-Gutierrez, Hina A. Rehman, Monica Serrano-Gonzalez, Nahuel Fittipaldi, Stephen D. Ayers, Paul Webb, Barbara M. Willey, Donald E. Low, James M. Musser

Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations

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2010 Randall J. Olsen, Madiha Ashraf, Vedia E. Gonulal, Ara A. Ayeras, Concepcion Cantu, Patrick R. Shea

ORCID

, Ronan K. Carroll, Tammy Humbird, Jamieson L. Greaver, Jody L. Swain, Ellen Chang, Willie Ragasa, Leslie Jenkins, Kevin P. Lally, Terry Blasdel and 2 other authors

Lower respiratory tract infection in cynomolgus macaques (Macaca fascicularis) infected with group A Streptococcus

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Patrick R. Shea

ORCID

, Kimmo Virtaneva, John J. Kupko, Stephen F. Porcella, William T. Barry, Fred A. Wright, Scott D. Kobayashi, Aaron Carmody, Robin M. Ireland, Daniel E. Sturdevant, Stacy M. Ricklefs, Imran Babar, Claire A. Johnson, Morag R. Graham, Donald J. Gardner and 4 other authors

Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus

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Stephen B. Beres

ORCID

, Ronan K. Carroll, Patrick R. Shea

ORCID

, Izabela Sitkiewicz, Juan Carlos Martinez-Gutierrez, Donald E. Low, Allison McGeer, Barbara M. Willey, Karen Green, Gregory J. Tyrrell, Thomas D. Goldman, Michael Feldgarden, Bruce W. Birren, Yuriy Fofanov, John Boos and 3 other authors

Molecular complexity of successive bacterial epidemics deconvoluted by comparative pathogenomics

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2008 Patrick R. Shea

ORCID

, Chandramohan S. Ishwad, Clareann H. Bunker, Alan L. Patrick, Lewis H. Kuller, Robert E. Ferrell

RNASEL and RNASEL-inhibitor variation and prostate cancer risk in Afro-Caribbeans

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