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All papers authored by John Horton

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2024 Jujun Zhou, Qin Chen, Ren Ren, Jie Yang, Bigang Liu, John R. Horton

ORCID

, Caleb Chang, Chuxuan Li, Leora Maksoud, Yifei Yang, Dante Rotili, Xing Zhang, Robert M. Blumenthal, Taiping Chen, Yang Gao and 3 other authors

Quinoline-based compounds can inhibit diverse enzymes that act on DNA

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2023 Jujun Zhou, John R. Horton

ORCID

, Gundeep Kaur, Qin Chen, Xuwen Li, Fabian Mendoza, Tao Wu, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng

Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga

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This paper is made freely available by the publisher.

Ren Ren, John R. Horton

ORCID

, Qin Chen, Jie Yang, Bin Liu, Yun Huang, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng

Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia

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This paper is made freely available by the publisher.

John R. Horton

ORCID

, Jujun Zhou, Qin Chen, Xing Zhang, Mark T. Bedford, Xiaodong Cheng

A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2

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This paper is made freely available by the publisher.

2021 Melissa B. Pappalardi

ORCID

, Kathryn Keenan, Mark Cockerill, Wendy A. Kellner, Alexandra Stowell, Christian Sherk, Kristen Wong, Sarath Pathuri, Jacques Briand, Michael Steidel, Philip Chapman, Arthur Groy, Ashley K. Wiseman, Charles F. McHugh, Nino Campobasso

ORCID

and 47 other authors

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

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Jujun Zhou, John R. Horton

ORCID

, Robert M. Blumenthal, Xing Zhang, Xiaodong Cheng

Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix

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This paper is made freely available by the publisher.

2019 John R. Horton

ORCID

, Clayton B. Woodcock, Sifa B. Opot, Norbert O. Reich, Xing Zhang, Xiaodong Cheng

ORCID

The cell cycle-regulated DNA adenine methyltransferase CcrM opens a bubble at its DNA recognition site

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This paper is made freely available by the publisher.

Shaobo Dai, John R. Horton

ORCID

, Clayton B. Woodcock, Alex W. Wilkinson, Xing Zhang, Or Gozani

ORCID

, Xiaodong Cheng

ORCID

Structural basis for the target specificity of actin histidine methyltransferase SETD3

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