William J. Martin

All papers authored by William J. Martin

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2023 Dimitri Krainc

, William J. Martin

, Bradford Casey

, Frances E. Jensen, Sarah Tishkoff

, William Z. Potter

, Steven E. Hyman

Shifting the trajectory of therapeutic development for neurological and psychiatric disorders

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This paper is made freely available by the publisher.

2021 Jie Lisa Ji

, Markus Helmer

, Clara Fonteneau, Joshua B. Burt, Zailyn Tamayo, Jure Demšar, Brendan D. Adkinson

, Aleksandar Savić, Katrin H. Preller

, Flora Moujaes, Franz X. Vollenweider

, William J. Martin

, Grega Repovš, Youngsun T. Cho

, Christopher Pittenger and 2 other authors

Mapping brain-behavior space relationships along the psychosis spectrum

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2020 Joseph R. Driscoll, Tanya L. Wallace

, Kasra A. Mansourian, William J. Martin

, Elyssa B. Margolis

Differential modulation of ventral tegmental area circuits by the nociceptin/orphanin FQ system

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2018 Joshua B. Burt, Murat Demirtaş, William J. Eckner, Natasha M. Navejar

, Jie Lisa Ji, William J. Martin

, Alberto Bernacchia, Alan Anticevic, John D. Murray

Hierarchy of transcriptomic specialization across human cortex captured by structural neuroimaging topography

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2015 J. A. M. Smith, D. L. Bourdet, O. T. Daniels, Y.-S. Ding, J.-D. Gallezot, S. Henry, K. H. S. Kim, S. Kshirsagar, W. J. Martin

, G. P. Obedencio, E. Stangeland, P. R. Tsuruda, W. Williams, R. E. Carson, S. T. Patil

Erratum: Preclinical to clinical translation of CNS transporter occupancy of TD-9855, a novel norepinephrine and serotonin reuptake inhibitor(International Journal of Neuropsychopharmacology (2015) 18:2 DOI: 10.1093/ijnp/pyu027)

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2014 Jacqueline Am M. Smith, D. Bourdet, Dl L. Patil, Ot T. Daniels, Y.-S. Ding, J.-D. Gallezot, S. Henry, Khs H. S. Kim, S. Kshirsagar, Wj J. Martin

, Gp P. Obedencio, E. Stangeland, Pr R. Tsuruda, W. Williams, Re E. Carson and 2 other authors

Preclinical to Clinical Translation of CNS Transporter Occupancy of TD-9855, a Novel Norepinephrine and Serotonin Reuptake Inhibitor

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Sharath S. Hegde, Adam D. Hughes, Yan Chen, Tod Steinfeld, Jeffrey R. Jasper, Tae-Weon Lee, Alexander McNamara, William J. Martin

, M. Teresa Pulido-Rios, Mathai Mammen

Pharmacologic Characterization of GSK-961081 (TD-5959), a First-in-Class Inhaled Bifunctional Bronchodilator Possessing Muscarinic Receptor Antagonist and β₂-Adrenoceptor Agonist Properties

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2013 Fei Shen, Pamela R. Tsuruda, Jacqueline A. M. Smith, Glenmar P. Obedencio, William J. Martin

Relative Contributions of Norepinephrine and Serotonin Transporters to Antinociceptive Synergy between Monoamine Reuptake Inhibitors and Morphine in the Rat Formalin Model

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M. Teresa R. Pulido Rios, Alexander McNamara, Glenmar P. Obedencio, Yuhua Ji, Sarah Jaw-Tsai, William J. Martin

, Sharath S. Hegde

In Vivo Pharmacological Characterization of TD-4208, a Novel Lung-Selective Inhaled Muscarinic Antagonist with Sustained Bronchoprotective Effect in Experimental Animal Models

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2012 Lori Jean Van Orden, Priscilla M. Van Dyke, D. Roland Saito, Timothy J. Church, Ray Chang, Jacqueline A. M. Smith, William J. Martin

, Sarah Jaw-Tsai, Eric L. Stangeland

A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: Synthesis and structure–activity relationships

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Alexander McNamara, Tod Steinfeld, Maria Teresa Pulido-Rios, Eric Stangeland, Sharath S. Hegde, Mathai Mammen, William J. Martin

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β2-adrenoceptor agonist (MABA)

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2011 Qingmei Hong, Raman K. Bakshi, Brenda L. Palucki, Min K. Park, Zhixiong Ye, Shuwen He, Patrick G. Pollard, Iyassu K. Sebhat, Jian Liu, Liangqin Guo, Doreen E. Cashen, William J. Martin

, David H. Weinberg, Tanya MacNeil, Rui Tang and 11 other authors

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist

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Alexander McNamara, Maria Teresa Pulido-Rios, Sharath S. Hegde, William J. Martin

Application of the classical Einthoven model of bronchoconstriction to the study of inhaled bronchodilators in rodents

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2010 Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou, Brett Taylor, Ronsar Eid, Michael H. Fisher, William H. Parsons, Mathew J. Wyvratt, Kathryn A. Lyons, Tracy Klatt, Xiaohua Li, Sanjeev Kumar, Brande Williams, John Felix, Birgit T. Priest and 11 other authors

Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain

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Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou, Brett Taylor, Michael H. Fisher, Mathew J. Wyvratt, Kathy Lyons, Tracy Klatt, Xiaohua Li, Sanjeev Kumar, Brande Williams, John Felix, Birgit T. Priest, Richard M. Brochu, Vivien Warren and 8 other authors

Substituted biaryl pyrazoles as sodium channel blockers

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Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou, Michael H. Fisher, Mathew J. Wyvratt, Kathy Lyons, Tracy Klatt, Xiaohua Li, Sanjeev Kumar, Brande Williams, John Felix, Birgit T. Priest, Richard M. Brochu, Vivien Warren, McHardy Smith and 7 other authors

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers

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Liangqin Guo, Zhixiong Ye, Jian Liu, Shuwen He, Raman K. Bakshi, Iyassu K. Sebhat, Peter H. Dobbelaar, Qingmei Hong, Tianying Jian, James P. Dellureficio, Nancy N. Tsou, Richard G. Ball, David H. Weinberg, Tanya MacNeil, Rui Tang and 10 other authors

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4′-piperidine] based melanocortin subtype-4 receptor agonists

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Qingmei Hong, Raman K. Bakshi, James Dellureficio, Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Rui Tang, Rubana N. Kalyani, Tanya MacNeil, Aurawan Vongs, Charles I. Rosenblum and 16 other authors

Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands

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Shuwen He, Zhixiong Ye, Peter H. Dobbelaar, Iyassu K. Sebhat, Liangqin Guo, Jian Liu, Tianying Jian, Yingjie Lai, Christopher L. Franklin, Raman K. Bakshi, James P. Dellureficio, Qingmei Hong, Nancy N. Tsou, Richard G. Ball, Doreen E. Cashen and 15 other authors

Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist

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Charles A. Blum, Timothy Caldwell, Xiaozhang Zheng, Rajagopal Bakthavatchalam, Scott Capitosti, Harry Brielmann, Stéphane De Lombaert, Mark T. Kershaw, David Matson, James E. Krause, Daniel Cortright, Marci Crandall, William J. Martin

, Beth Ann Murphy, Susan Boyce and 8 other authors

Discovery of Novel 6,6-Heterocycles as Transient Receptor Potential Vanilloid (TRPV1) Antagonists

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All papers authored by William J. Martin