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All papers authored by Giovanna Mallucci

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2023 Julie Qiaojin Lin

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, Deepak Khuperkar

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, Sofia Pavlou, Stanislaw Makarchuk

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, Nikolaos Patikas

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, Flora Cy Y. Lee

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, Jianning Kang

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, Sarah F. Field, Julia M. Zbiegly

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, David Md Bailey, Joshua L. Freeman, Jernej Ule

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, Emmanouil Metzakopian

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, Marc‐David Ruepp

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, Giovanna R. Mallucci

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HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion

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Marco Preußner

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, Heather L. Smith, Daniel Hughes

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, Min Zhang, Ann‐Kathrin Emmerichs, Silvia Scalzitti, Diego Peretti, Dean Swinden, Alexander Neumann, Tom Haltenhof, Giovanna R. Mallucci

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ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo

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2021 Diego Peretti, Heather L. Smith, Nicholas Verity, Ibrahim Humoud, Lis de Weerd, Dean P. Swinden, Joseph Hayes, Giovanna R. Mallucci

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TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection

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2020 Giovanna R. Mallucci

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, David Klenerman, David C. Rubinsztein

Developing Therapies for Neurodegenerative Disorders: Insights from Protein Aggregation and Cellular Stress Responses

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Daniel T. Hughes

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, Mark Halliday, Heather L. Smith, Nicholas C. Verity, Colin Molloy

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, Helois Radford

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, Adrian J. Butcher, Giovanna R. Mallucci

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Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice

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Heather L. Smith, Oliver J. Freeman, Adrian J. Butcher, Staffan Holmqvist, Ibrahim Humoud, Tobias Schätzl, Daniel T. Hughes, Nicholas C. Verity, Dean P. Swinden, Joseph Hayes, Lis de Weerd, David H. Rowitch, Robin J. M. Franklin, Giovanna R. Mallucci

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Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

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John R. P. Knight, Gavin Garland, Tuija Pöyry, Emma Mead, Nikola Vlahov, Aristeidis Sfakianos, Stefano Grosso, Fabio De-Lima-Hedayioglu, Giovanna R. Mallucci

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, Tobias von der Haar, C. Mark Smales, Owen J. Sansom, Anne E. Willis

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Control of translation elongation in health and disease

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2019 Mark Halliday, Giovanna R. Mallucci

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Translating translation in Down syndrome

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Vicente Gonzalez-Teuber, Hector Albert-Gasco, Vincent C. Auyeung, Feroz R. Papa, Giovanna R. Mallucci

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, Claudio Hetz

Small Molecules to Improve ER Proteostasis in Disease

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2018 Roberta Cagnetta, Hovy Ho-Wai Wong, Christian K. Frese, Giovanna R. Mallucci

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, Jeroen Krijgsveld, Christine E. Holt

Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

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Barry Boland, Wai Haung Yu, Olga Corti, Bertrand Mollereau, Alexandre Henriques, Erwan Bezard, Greg M. Pastores, David C. Rubinsztein, Ralph A. Nixon, Michael R. Duchen, Giovanna R. Mallucci

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, Guido Kroemer, Beth Levine, Eeva-Liisa Eskelinen, Fanny Mochel and 4 other authors

Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing

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Lisa Michelle Restelli, Björn Oettinghaus, Mark Halliday, Cavit Agca, Maria Licci, Lara Sironi, Claudia Savoia, Jürgen Hench, Markus Tolnay, Albert Neutzner, Alexander Schmidt, Anne Eckert, Giovanna Mallucci

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, Luca Scorrano, Stephan Frank

Neuronal Mitochondrial Dysfunction Activates the Integrated Stress Response to Induce Fibroblast Growth Factor 21

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Susan W. Robinson, Julie-Myrtille Bourgognon, Jereme G. Spiers, Carlo Breda, Susanna Campesan, Adrian Butcher, Giovanna R. Mallucci

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, David Dinsdale, Nobuhiro Morone

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, Raj Mistry, Tim M. Smith, Maria Guerra-Martin, R. A. John Challiss, Flaviano Giorgini, Joern R. Steinert

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Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

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Daniel Hughes

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, Giovanna R. Mallucci

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The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway

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2017 Mark Halliday, Daniel Hughes, Giovanna R. Mallucci

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Fine-tuning PERK signaling for neuroprotection

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Mark Halliday, Giovanna R. Mallucci

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Reply: Trazodone to change the risk of neurodegeneration: bedside to bench

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Mark Halliday, Helois Radford, Karlijn A. M. Zents, Collin Molloy, Julie A. Moreno, Nicholas C. Verity, Ewan Smith, Catharine A. Ortori, David A. Barrett, Martin Bushell, Giovanna R. Mallucci

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Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice

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Amandine Bastide, Diego Peretti, John R. P. Knight, Stefano Grosso, Ruth V. Spriggs, Xavier Pichon, Thomas Sbarrato, Anne Roobol, Jo Roobol, Davide Vito, Martin Bushell, Tobias von der Haar, C. Mark Smales, Giovanna R. Mallucci

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, Anne E. Willis

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3

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2016 Sophie J. Bradley, David J. White, Bradley Sj, Julie-Myrtille Bourgognon, Bourgognon Jm, Helen E. Sanger, Sanger He, Adrian J. Mogg, Nicholas Verity, Adrian J. Butcher, Mogg Aj, Julie A. Moreno, White Dj, Butcher Aj, Jennifer M. Edwards and 15 other authors

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

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Smith Hl, Heather L. Smith, Mallucci Gr, Giovanna R. Mallucci

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The unfolded protein response: mechanisms and therapy of neurodegeneration

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