Gillian Leigh Dornan

All papers authored by Gillian Leigh Dornan

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2021 Philipp Alexander Koch

, Gillian Leigh Dornan

, Manuel Hessenberger

, Volker Haucke

The Molecular Mechanisms Mediating Class II PI 3‐Kinase Function in Cell Physiology

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Sarah Hostachy

, Tillmann Utesch, Katy Franke, Gillian Leigh Dornan

, David Furkert

, Berke Türkaydin

, Volker Haucke, Han Sun, Dorothea Fiedler

Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs

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2019 Gillian L. Dornan

, Jordan T. B. Stariha

, Manoj K. Rathinaswamy, Cameron J. Powell, Martin J. Boulanger, John E. Burke

Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases

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2018 Gillian L. Dornan

, Udit Dalwadi, David J. Hamelin, Reece M. Hoffmann, Calvin K. Yip, John E. Burke

Probing the Architecture, Dynamics, and Inhibition of the PI4KIIIα/TTC7/FAM126 Complex

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Gillian L. Dornan

, John E. Burke

Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases

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2017 Ana Casañal

, Ananthanarayanan Kumar

, Chris H. Hill

, Ashley D. Easter

, Paul Emsley

, Gianluca Degliesposti

, Yuliya Gordiyenko

, Balaji Santhanam

, Jana Wolf

, Katrin Wiederhold, Gillian L. Dornan

, Mark Skehel

, Carol V. Robinson

, Lori A. Passmore

Architecture of eukaryotic mRNA 3′-end processing machinery

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Andrew J. Takeda, Yu Zhang, Gillian L. Dornan

, Braden D. Siempelkamp, Meredith L. Jenkins, Helen F. Matthews, Joshua J. McElwee, Weimin Bi, Filiz O. Seeborg, Helen C. Su, John E. Burke, Carrie L. Lucas

Novel PIK3CD mutations affecting N-terminal residues of p110δ cause activated PI3Kδ syndrome (APDS) in humans

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Gillian L. Dornan

, Braden D. Siempelkamp, Meredith L. Jenkins, Oscar Vadas, Carrie L. Lucas, John E. Burke

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1

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O. Vadas, M. L. Jenkins, G. L. Dornan

, J. E. Burke

Using Hydrogen–Deuterium Exchange Mass Spectrometry to Examine Protein–Membrane Interactions

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2016 Nobutaka Kato, Eamon Comer, Tomoyo Sakata-Kato, Arvind Sharma, Manmohan Sharma, Micah Maetani, Jessica Bastien, Nicolas M. Brancucci, Joshua A. Bittker, Victoria Corey, David Clarke, Emily R. Derbyshire, Gillian L. Dornan

, Sandra Duffy, Sean Eckley and 37 other authors

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

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Florentine U. Rutaganira, Melissa L. Fowler, Jacob A. McPhail, Michael A. Gelman, Khanh Nguyen, Anming Xiong, Gillian L. Dornan

, Brandon Tavshanjian, Jeffrey S. Glenn, Kevan M. Shokat, John E. Burke

Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ

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Gillian Leigh Dornan

, Jacob A. McPhail, John E. Burke

Type III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease

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2014 Eeson Rajendra, Vibe H. Oestergaard, Frédéric Langevin, Meng Wang, Gillian L. Dornan

, Ketan J. Patel, Lori A. Passmore

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

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All papers authored by Gillian Leigh Dornan