Florence Raynaud - Dissemin

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All papers authored by Florence Raynaud

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2024 Markus Ritzefeld

ORCID

, Leran Zhang, Zhangping Xiao, Sebastian A. Andrei, Olivia Boyd

ORCID

, Naoko Masumoto, Ursula R. Rodgers, Markus Artelsmair

ORCID

, Lea Sefer, Angela Hayes, Efthymios-Spyridon Gavriil, Florence I. Raynaud

ORCID

, Rosemary Burke, Julian Blagg, Henry S. Rzepa

ORCID

and 4 other authors

Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase

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2023 Christina Guo, Adam Sharp, Bora Gurel

ORCID

, Mateus Crespo

ORCID

, Ines Figueiredo, Suneil Jain, Ursula Vogl, Jan Rekowski

ORCID

, Mahtab Rouhifard, Lewis Gallagher

ORCID

, Wei Yuan, Suzanne Carreira

ORCID

, Khobe Chandran, Alec Paschalis, Ilaria Colombo

ORCID

and 34 other authors

Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance

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Habib Bouguenina, Stephanos Nicolaou, Yann-Vaï Le Bihan, Elizabeth A. Bowling, Cheyenne Calderon, John J. Caldwell, Brinley Harrington, Angela Hayes, P. Craig McAndrew, Costas Mitsopoulos, Fernando Jr. Sialana, Andrea Scarpino

ORCID

, Mark Stubbs, Arjun Thapaliya, Siddhartha Tyagi and 10 other authors

iTAG an optimized IMiD-induced degron for targeted protein degradation in human and murine cells

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Tom Woelders

ORCID

, Victoria L. Revell

ORCID

, Benita Middleton, Katrin Ackermann

ORCID

, Manfred Kayser

ORCID

, Florence I. Raynaud

ORCID

, Debra J. Skene

ORCID

, Roelof A. Hut

Machine learning estimation of human body time using metabolomic profiling

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Alice C. Harnden

ORCID

, Owen A. Davis, Gary M. Box, Angela Hayes, Louise D. Johnson, Alan T. Henley, Alexis K. de Haven Brandon, Melanie Valenti, Kwai-Ming J. Cheung, Alfie Brennan, Rosemary Huckvale, Olivier A. Pierrat, Rachel Talbot, Michael D. Bright, Hafize Aysin Akpinar and 14 other authors

Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones

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A. Elisa Pasqua

ORCID

, Swee Y. Sharp, Nicola E. A. Chessum

ORCID

, Angela Hayes, Loredana Pellegrino, Michael J. Tucker, Asadh Miah, Birgit Wilding, Lindsay E. Evans, Carl S. Rye, N. Yi Mok

ORCID

, Manjuan Liu, Alan T. Henley, Sharon Gowan, Emmanuel De Billy and 8 other authors

HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Susana Banerjee

ORCID

, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle

ORCID

, Florence Raynaud

ORCID

, Ruth Riisnaes

ORCID

, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout and 14 other authors

Supplementary Table from A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Susana Banerjee

ORCID

, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle

ORCID

, Florence Raynaud

ORCID

, Ruth Riisnaes

ORCID

, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout and 14 other authors

Data from A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Susana Banerjee

ORCID

, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle

ORCID

, Florence Raynaud

ORCID

, Ruth Riisnaes

ORCID

, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout and 14 other authors

Supplementary Figure from A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

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2022 Olivier A. Pierrat, Manjuan Liu, Gavin W. Collie, Kartika Shetty, Matthew J. Rodrigues

ORCID

, Yann-Vaï Le Bihan, Emma A. Gunnell, P. Craig McAndrew, Mark Stubbs, Martin G. Rowlands, Norhakim Yahya, Erald Shehu, Rachel Talbot, Lisa Pickard, Benjamin R. Bellenie and 19 other authors

Discovering cell-active BCL6 inhibitors: effectively combining biochemical HTS with multiple biophysical techniques, X-ray crystallography and cell-based assays

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This paper is made freely available by the publisher.

Afia Naseem

ORCID

, Akos Pal, Sharon Gowan, Yasmin Asad, Adam Donovan, Csilla Temesszentandrási-Ambrus

ORCID

, Emese Kis, Zsuzsanna Gaborik, Gurdip Bhalay, Florence Raynaud

ORCID

Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay—Biological Implications

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This paper was not found in any repository, but could be made available legally by the author.

P. Workman, P. A. Clarke, R. Te Poele, M. Powers, G. Box, E. De Billy, A. De Haven Brandon, A. Hallsworth, A. Hayes, H. McCann, S. Sharp, M. Valenti, F. I. Raynaud

ORCID

, S. A. Eccles, M. Cheeseman and 1 other authors

Discovery and validation of biomarkers to support clinical development of NXP800: A first-in-class orally active, small-molecule HSF1 pathway inhibitor

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A. Margarido, B. Whitton, E. Arwert, M. Cheeseman, A. Kalusa, G. Davison, R. Salimraj, O. Pierrat, M. Richards, H. dos Santos Costa, P. Meister, A. Hayes, E. Reeves, E. James, R. Burke and 5 other authors

Investigating the effects of ERAP1 inhibition on antigen presentation and the tumour immune response

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A. Harnden, R. Huckvale, K. M. Cheung, O. Davis, O. Pierrat, Rachel Talbot, G. Box, M. Bright, A. Akpinar, D. Miller, A. Hayes, E. Gunnell, Y. V. Le Bihan, R. Burke, V. Kirkin and 5 other authors

Improved binding affinity and pharmacokinetics enables sustained degradation of BCL6 in vivo

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C. Guo, A. Sharp, U. Vogl, I. Colombo, A. Stathis, S. Jain, K. Chandran, C. Tiu, A. Paschalis, R. E. Matthews, I. Figueiredo, J. Rekowski, C. Yap, M. de los Dolores Fenor de la Maza, A. Turner and 5 other authors

454O A phase (Ph) I/II trial of the CXCR2 antagonist AZD5069 in combination with enzalutamide (ENZA) in patients (pts) with metastatic castration resistant prostate cancer (mCRPC)

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This paper was not found in any repository, but could be made available legally by the author.

Susana Banerjee

ORCID

, Vasiliki Michalarea

ORCID

ORCID

, Alvaro Ingles Garces

ORCID

, Andrea Biondo

ORCID

, Ionut-Gabriel Funingana

ORCID

, Martin Little

ORCID

ORCID

, Florence Raynaud

ORCID

, Ruth Riisnaes

ORCID

ORCID

, Sue Chua

ORCID

ORCID

, Joanna C. Porter

ORCID

ORCID

and 14 other authors

A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

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This paper was not found in any repository, but could be made available legally by the author.

Owen A. Davis, Kwai-Ming J. Cheung, Alfie Brennan, Matthew G. Lloyd

ORCID

, Matthew J. Rodrigues

ORCID

, Olivier A. Pierrat, Gavin W. Collie

ORCID

, Yann-Vaï Le Bihan

ORCID

, Rosemary Huckvale, Alice C. Harnden

ORCID

, Ana Varela, Michael D. Bright, Paul Eve, Angela Hayes, Alan T. Henley and 10 other authors

Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors

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Rosemary Huckvale, Alice C. Harnden

ORCID

, Kwai-Ming J. Cheung, Olivier A. Pierrat, Rachel Talbot, Gary M. Box, Alan T. Henley, Alexis K. de Haven Brandon, Albert E. Hallsworth, Michael D. Bright, Hafize Aysin Akpinar, Daniel S. J. Miller, Dalia Tarantino, Sharon Gowan, Angela Hayes and 15 other authors

Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo

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This paper is made freely available by the publisher.

This paper is made freely available by the publisher.

Rubens Paula Junior, Nathália Martins Sonehara, Bruna Victorasso Jardim-Perassi, Akos Pal, Yasmin Asad, Luiz Gustavo Almeida Chuffa, Roger Chammas, Florence I. Raynaud

ORCID

, Debora A. P. C. Zuccari

Presence of human breast cancer xenograft changes the diurnal profile of amino acids in mice

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