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All papers authored by Huadong Chen

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2023 Huadong Chen

ORCID

, Morgan E. Diolaiti, Patrick C. O'Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Supplementary Table from A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Huadong Chen

ORCID

, Morgan E. Diolaiti, Patrick C. O'Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Supplementary Data from A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Huadong Chen

ORCID

, Morgan E. Diolaiti, Patrick C. O'Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Data from A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Patrick C. O'Leary, Huadong Chen

ORCID

, Yagmur U. Doruk, Tess Williamson

ORCID

, Benjamin Polacco

ORCID

, Andrew S. McNeal, Tanushree Shenoy

ORCID

, Nupura Kale, Julia Carnevale, Erica Stevenson, David A. Quigley, Jonathan Chou, Felix Y. Feng, Danielle L. Swaney, Nevan J. Krogan and 3 other authors

Supplementary Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Patrick C. O'Leary, Huadong Chen

ORCID

, Yagmur U. Doruk, Tess Williamson

ORCID

, Benjamin Polacco

ORCID

, Andrew S. McNeal, Tanushree Shenoy

ORCID

, Nupura Kale, Julia Carnevale, Erica Stevenson, David A. Quigley, Jonathan Chou, Felix Y. Feng, Danielle L. Swaney, Nevan J. Krogan and 3 other authors

Data from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Patrick C. O'Leary, Huadong Chen

ORCID

, Yagmur U. Doruk, Tess Williamson

ORCID

, Benjamin Polacco

ORCID

, Andrew S. McNeal, Tanushree Shenoy

ORCID

, Nupura Kale, Julia Carnevale, Erica Stevenson, David A. Quigley, Jonathan Chou, Felix Y. Feng, Danielle L. Swaney, Nevan J. Krogan and 3 other authors

Supplementary Figure from Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

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This paper is made freely available by the publisher.

Li‐Min Wang

ORCID

, Pingyuan Wang

ORCID

, Xiao‐Min Chen

ORCID

, Hui Yang

ORCID

, Shan‐Shan Song, Zilan Song, Li Jia

ORCID

, Hua‐Dong Chen

ORCID

, Xu‐Bin Bao, Ne Guo

ORCID

, Xia‐Juan Huan, Yong Xi, Yan‐Yan Shen, Xin‐Ying Yang, Yi Su and 8 other authors

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

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This paper was not found in any repository, but could be made available legally by the author.

2022 Patrick C. O'Leary

ORCID

, Huadong Chen

ORCID

, Yagmur U. Doruk

ORCID

, Tess Williamson

ORCID

, Benjamin Polacco

ORCID

, Andrew S. McNeal

ORCID

, Tanushree Shenoy

ORCID

ORCID

, Julia Carnevale

ORCID

, Erica Stevenson

ORCID

, David A. Quigley

ORCID

, Jonathan Chou

ORCID

, Felix Y. Feng

ORCID

, Danielle L. Swaney

ORCID

, Nevan J. Krogan

ORCID

and 3 other authors

Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2

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This paper was not found in any repository, but could be made available legally by the author.

Huadong Chen

ORCID

, Morgan E. Diolaiti

ORCID

, Patrick C. O'Leary

ORCID

ORCID

, Nevan J. Krogan

ORCID

ORCID

, Alan Ashworth

ORCID

A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor

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This paper was not found in any repository, but could be made available legally by the author.

Ne Guo

ORCID

, Meng-Zhu Li, Li-Min Wang, Hua-Dong Chen

ORCID

, Shan Song, Ze-Hong Miao, Jin-Xue He

Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion

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This paper is made freely available by the publisher.

2021 Ning Zhang, Yu-Nan Tian, Li-Na Zhou, Meng-Zhu Li, Hua-Dong Chen

ORCID

, Shan Song, Xia-Juan Huan, Xu-Bin Bao, Ao Zhang, Ze-Hong Miao

ORCID

ORCID

Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer

Download from www.nature.com

This paper is made freely available by the publisher.

2020 Yu-Nan Tian, Hua-Dong Chen

ORCID

, Chang-Qing Tian, Ying-Qing Wang, Ze-Hong Miao

Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter

Download from www.nature.com

This paper is made freely available by the publisher.

2019 Chang-Qing Tian, Lin Chen, Hua-Dong Chen

ORCID

, Xia-Juan Huan, Jian-Ping Hu, Jing-Kang Shen, Bing Xiong, Ying-Qing Wang, Ze-Hong Miao

Inhibition of the BET family reduces its new target gene IDO1 expression and the production of l-kynurenine

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This paper is made freely available by the publisher.

Hua-Dong Chen

ORCID

, Chuan-Huizi Chen, Yu-Ting Wang, Ne Guo, Yu-Nan Tian, Xia-Juan Huan, Shan Song, Jin-Xue He, Ze-Hong Miao

Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity

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This paper is made freely available by the publisher.

2018 Yu-Ting Wang

ORCID

, Bo Yuan, Hua-Dong Chen

ORCID

, Lin Xu, Yu-Nan Tian, Ao Zhang, Jin-Xue He, Ze-Hong Miao

Acquired resistance of phosphatase and tensin homolog-deficient cells to poly(ADP-ribose) polymerase inhibitor and Ara-C mediated by 53BP1 loss and SAMHD1 overexpression

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This paper was not found in any repository, but could be made available legally by the author.

2017 Bo Yuan, Na Ye, Shan Song, Yu-Ting Wang, Zilan Song, Hua-Dong Chen

ORCID

, Chuan-Huizi Chen, Xia-Juan Huan, Ying-Qing Wang, Yi Su, Yan Shen, Yi-Ming Sun, Xin-Ying Yang, Yi Chen, Shi-Yan Guo and 7 other authors

Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials

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