Brian Hudson - Dissemin

Papers authored by Brian Hudson

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2014 Adrian J. Butcher, Brian D. Hudson

, Bharat Shimpukade, Elisa Alvarez-Curto, Rudi Prihandoko, Trond Ulven, Graeme Milligan, Andrew B. Tobin

Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4*

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Even Fjære, Ulrike L. Aune, Kristin Røen, Alison H. Keenan, Tao Ma, Tao, Kamil Borkowski, Kamil Borokowsky, David M. Kristensen, Guy W. Novotny, Thomas Mandrup-Poulsen, Brian D. Hudson

, Graeme Milligan, Yannan Xi, John W. Newman and 4 other authors

Indomethacin Treatment Prevents High Fat Diet-induced Obesity and Insulin Resistance but Not Glucose Intolerance in C57BL/6J Mice*

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Graeme Milligan, Trond Ulven, Hannah Murdoch, Brian D. Hudson

G-protein-coupled receptors for free fatty acids: Nutritional and therapeutic targets

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2013 Amanda E. MacKenzie, Gianluigi Caltabiano, Toby C. Kent, Laura Jenkins, Jennifer E. McCallum, Brian D. Hudson

, Stuart A. Nicklin, Lindsay Fawcett, Rachel Lane, Rachel Markwick, Steven J. Charlton, Graeme Milligan

The Antiallergic Mast Cell Stabilizers Lodoxamide and Bufrolin as the First High and Equipotent Agonists of Human and Rat GPR35

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H. J. Dranse, M. E. M. Kelly, B. D. Hudson

Drugs or diet? – Developing novel therapeutic strategies targeting the free fatty acid family of GPCRs

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Brian D. Hudson

, Bharat Shimpukade, Amanda E. Mackenzie, Adrian J. Butcher, John D. Pediani, Elisabeth Christiansen, Helen Heathcote, Andrew B. Tobin, Trond Ulven, Graeme Milligan

The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

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Brian D. Hudson

, Hannah Murdoch, Graeme Milligan

Minireview: The Effects of Species Ortholog and SNP Variation on Receptors for Free Fatty Acids

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Brian D. Hudson

, Maria E. Due-Hansen, Elisabeth Christiansen, Anna Mette Hansen

, Amanda E. Mackenzie, Hannah Murdoch, Sunil K. Pandey, Richard J. Ward, Rudi Marquez, Irina G. Tikhonova, Trond Ulven, Graeme Milligan

Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor*

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Elisabeth Christiansen, Steffen V. F. Hansen, Christian Urban, Brian D. Hudson

, Edward T. Wargent, Manuel Grundmann, Laura Jenkins, Mohamed Zaibi, Claire J. Stocker, Evi Kostenis, Susanne Ullrich, Matthias U. Kassack, Graeme Milligan, Michael A. Cawthorne, Trond Ulven

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

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Brian D. Hudson

, Trond Ulven, Graeme Milligan

The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs

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This paper was not found in any repository, but could be made available legally by the author.

Elisabeth Christiansen, Maria E. Due-Hansen, Christian Urban, Manuel Grundmann, Johannes Schmidt, Steffen V. F. Hansen, Brian D. Hudson

, Mohamed Zaibi, Stine B. Markussen, Ellen Hagesaether, Graeme Milligan, Michael A. Cawthorne, Evi Kostenis, Matthias U. Kassack, Trond Ulven

Discovery of a Potent and Selective Free Fatty Acid Receptor 1 Agonist with Low Lipophilicity and High Oral Bioavailability

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2012 Brian D. Hudson

, Irina G. Tikhonova, Sunil K. Pandey, Trond Ulven, Graeme Milligan

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3*

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Brian D. Hudson

, Elisabeth Christiansen, Irina G. Tikhonova, Manuel Grundmann, Evi Kostenis, David R. Adams, Trond Ulven, Graeme Milligan

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

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Elisabeth Christiansen, Maria E. Due-Hansen, Christian Urban, Manuel Grundmann, Ralf Schröder, Brian D. Hudson

, Graeme Milligan, Michael A. Cawthorne, Evi Kostenis, Matthias U. Kassack, Trond Ulven

Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists: Mesylpropoxy Appendage Lowers Lipophilicity and Improves ADME Properties

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Bharat Shimpukade, Brian D. Hudson

, Christine Kiel Hovgaard, Graeme Milligan, Trond Ulven

Discovery of a Potent and Selective GPR120 Agonist

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Brian D. Hudson

, Melanie E. M. Kelly

Identification of Novel Competing β₂AR Phospho-Extracellular Signal Regulated Kinase 1/2 Signaling Pathways in Human Trabecular Meshwork Cells

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Selim Terhzaz

, Pablo Cabrero, Joris H. Robben, Jonathan C. Radford, Brian D. Hudson

, Graeme Milligan, Julian A. T. Dow

, Shireen-A. Davies

Mechanism and Function of Drosophila capa GPCR: A Desiccation Stress-Responsive Receptor with Functional Homology to Human NeuromedinU Receptor

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2011 Brian D. Hudson

, Meggie Beazley, Anna-Maria Szczesniak, Alex Straiker, Melanie E. M. Kelly

Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists

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Nicola J. Smith, Richard J. Ward, Leigh A. Stoddart, Brian D. Hudson

, Evi Kostenis, Trond Ulven, Joanne C. Morris, Christian Tränkle, Irina G. Tikhonova, David R. Adams, Graeme Milligan

Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator

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Johannes Schmidt, Nicola J. Smith, Elisabeth Christiansen, Irina G. Tikhonova, Manuel Grundmann, Brian D. Hudson

, Richard J. Ward, Christel Drewke, Graeme Milligan, Evi Kostenis, Trond Ulven

Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists

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Papers authored by Brian Hudson