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All papers authored by Joseph Trapani

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2023 Deborah Meyran

ORCID

, Joe Jiang Zhu

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, Jeanne Butler, Daniela Tantalo

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, Sean MacDonald, Thu Ngoc Nguyen

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ORCID

ORCID

, Criselle D’Souza

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, Vicky Mengfei Qin

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, Aaron Harrison, Kevin Sek

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, Pasquale Petrone, Kevin Thia

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and 14 other authors

T _STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models

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Marina E. Ivanova, Natalya Lukoyanova

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, Sony Malhotra

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ORCID

, Joseph A. Trapani

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, Ilia Voskoboinik

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, Helen R. Saibil

ORCID

The pore conformation of lymphocyte perforin

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2020 Jack D. Chan

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, Bianca von Scheidt, Bianca Scheidt, Bijun Zeng, Amanda J. Oliver

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, Ashleigh S. Davey

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, Aesha I. Ali, Ranjeny Thomas

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, Joseph A. Trapani

ORCID

, Phillip K. Darcy

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, Michael H. Kershaw

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, Riccardo Dolcetti

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, Clare Y. Slaney

ORCID

Enhancing chimeric antigen receptor T‐cell immunotherapy against cancer using a nanoemulsion‐based vaccine targeting cross‐presenting dendritic cells

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Adrian W. Hodel

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, Jesse A. Rudd-Schmidt

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, Joseph A. Trapani

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, Ilia Voskoboinik

ORCID

, Bart W. Hoogenboom

ORCID

Lipid specificity of the immune effector perforin

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2017 Stephen Opat, Anna C. Hearps, Kevin Thia, Agnes Yuen, Ben Rogers, Mkunde Chachage, Gregory Moore, Jake Shortt, Georgina Ryland, Piers Blombery, Anthony P. Schwarer, Tahereh Noori, Joseph A. Trapani

ORCID

, Anthony Jaworowski, Ilia Voskoboinik

ORCID

Adaptive reprogramming of NK cells in X-linked lymphoproliferative syndrome

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Sathana Dushyanthen, Zhi Ling Teo, Franco Caramia, Peter Savas, Christopher P. Mintoff, Balaji Virassamy, Melissa A. Henderson, Stephen J. Luen, Mariam Mansour, Michael H. Kershaw, Joseph A. Trapani

ORCID

, Paul J. Neeson, Roberto Salgado, Grant A. McArthur, Justin M. Balko and 3 other authors

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

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Julie A. Spicer

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, Christian K. Miller, Patrick D. O'Connor, Jiney Jose, Kristiina M. Huttunen, Jagdish K. Jaiswal, William A. Denny, Hedieh Akhlaghi

ORCID

, Kylie A. Browne, Joseph A. Trapani

ORCID

Substituted arylsulphonamides as inhibitors of perforin-mediated lysis

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Marian L. Burr, Christina E. Sparbier, Yih-Chih Chan, James C. Williamson, Katherine Woods, Paul A. Beavis, Enid Y. N. Lam, Melissa A. Henderson, Charles C. Bell, Sabine Stolzenburg, Omer Gilan, Stuart Bloor, Tahereh Noori, David W. Morgens, Michael C. Bassik and 9 other authors

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

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Imran G. House, Colin M. House, Amelia J. Brennan, Omer Gilan, Mark A. Dawson, James C. Whisstock, Ruby Hp Law, Joseph A. Trapani

ORCID

, Ilia Voskoboinik

ORCID

Regulation of perforin activation and pre‐synaptic toxicity through C‐terminal glycosylation

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Paul Edgar Gray, Bella Shadur, Susan Russell, Richard Mitchell, Michael Buckley, Kerri Gallagher, Ian Andrews, Kevin Thia, Joseph A. Trapani

ORCID

, Edwin Philip Kirk, Ilia Voskoboinik

ORCID

Late-Onset Non-HLH Presentations of Growth Arrest, Inflammatory Arachnoiditis, and Severe Infectious Mononucleosis, in Siblings with Hypomorphic Defects in UNC13D

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Zia U. A. Mollah, Hong Sheng Quah, Kate L. Graham, Gaurang Jhala, Balasubramanian Krishnamurthy, Joanna Francisca M. Dharma, Jonathan Chee

ORCID

, Prerak M. Trivedi, Evan G. Pappas, Leanne Mackin, Edward P. F. Chu, Satoru Akazawa, Stacey Fynch, Charlotte Hodson, Andrew J. Deans and 6 other authors

Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon–Dependent Pathway

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Paul A. Beavis, Melissa A. Henderson, Lauren Giuffrida, Jane K. Mills, Kevin Sek, Ryan S. Cross, Alexander J. Davenport, Liza B. John, Sherly Mardiana, Clare Y. Slaney, Ricky W. Johnstone, Joseph A. Trapani

ORCID

, John Stagg, Sherene Loi, Lev Kats and 3 other authors

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

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Joseph A. Trapani

ORCID

Immunity, Granzymes and Cell Killing

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Sherly Mardiana, Liza B. John, Melissa A. Henderson, Clare Y. Slaney, Bianca von Scheidt, Lauren Giuffrida, Alexander J. Davenport, Joseph A. Trapani

ORCID

, Paul J. Neeson, Sherene Loi, Nicole M. Haynes, Michael H. Kershaw, Paul A. Beavis, Phillip K. Darcy

A Multifunctional Role for Adjuvant Anti-4-1BB Therapy in Augmenting Antitumor Response by Chimeric Antigen Receptor T Cells

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Daniella Brasacchio, Amber E. Alsop, Tahereh Noori, Mariam Lufti, Sweta Iyer, Kaylene J. Simpson, Phillip I. Bird, Ruth M. Kluck, Ricky W. Johnstone, Joseph A. Trapani

ORCID

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

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Julie A. Spicer, Christian K. Miller, Patrick D. O'Connor, Jiney Jose, Kristiina M. Huttunen, Jagdish K. Jaiswal, William A. Denny, Hedieh Akhlaghi, Kylie A. Browne, Joseph A. Trapani

ORCID

Benzenesulphonamide inhibitors of the cytolytic protein perforin

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Mikolaj Medon, Eva Vidacs, Stephin J. Vervoort

ORCID

, Jason Li, Misty R. Jenkins

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, Kelly M. Ramsbottom, Joseph A. Trapani

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, Mark J. Smyth, Phillip K. Darcy, Peter W. Atadja, Michael A. Henderson, Ricky W. Johnstone, Nicole M. Haynes

HDAC inhibitor panobinostat engages host innate immune defenses to promote the tumoricidal effects of trastuzumab in HER2+ tumors

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Carl Leung, Aw W. Hodel, Aj Brennan, Natalya Lukoyanova, Sharon Tran, Cm M. House, Sc C. Kondos, Jc C. Whisstock, Michelle A. Dunstone, Ja A. Trapani

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, Ilia Voskoboinik

ORCID

, Helen R. Saibil, Bw W. Hoogenboom

ORCID

Real-time visualization of perforin nanopore assembly

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2016 Clare Y. Slaney, Bianca von Scheidt, Alexander J. Davenport, Paul A. Beavis, Jennifer A. Westwood, Sherly Mardiana, David C. Tscharke, Sarah Ellis, H. Miles Prince, Joseph A. Trapani

ORCID

, Ricky W. Johnstone, Mark J. Smyth, Michele W. Teng, Aesha Ali, Zhiya Yu and 5 other authors

Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting

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