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GNAQ/GNA11 Mosaicism Causes Aberrant Calcium Signaling Susceptible to Targeted Therapeutics
UploadMolecular mechanism of muscarinic acetylcholine receptor M3 interaction with Gq
Download from doi.orgChemogenetic activation of G12 signaling enhances adipose tissue browning
Download from doi.orgClass B1 GPCR activation by an intracellular agonist
UploadMolecular mechanism of fatty acid activation of FFAR1
Download from doi.orgInsights into distinct signaling profiles of the µOR activated by diverse agonists
UploadCryo-EM structures of the β3 adrenergic receptor bound to solabegron and isoproterenol
UploadActivation and allosteric regulation of the orphan GPR88-Gi1 signaling complex
Download from doi.orgOZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz
Download from doi.orgCryo-EM structure of the human MT1–Gi signaling complex
UploadNoncanonical scaffolding of G αi and β-arrestin by G protein–coupled receptors
UploadDelineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs
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