Zoran Radic
0000-0003-0806-3869
UC San Diego
30 papers found
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Connectivity between surface and interior in catalytic subunits of acetylcholinesterases inferred from their X‐ray structures
Esterases
Cobinamide is a strong and versatile antioxidant that overcomes oxidative stress in cells, flies, and diabetic mice
Shifts in Backbone Conformation of Acetylcholinesterases upon Binding of Covalent Inhibitors, Reversible Ligands and Substrates
Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition
Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects
Enhancing Target Tissue Levels and Diminishing Plasma Clearance of Ionizing Zwitterionic Antidotes in Organophosphate Exposures
Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure
Correction: Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase.
Rational design, synthesis and evaluation of “smart”, uncharged bis‐oxime antidotes of OP inhibited human acetylcholinesterase
Pharmacokinetic Analysis of Ionizable Zwitterionic Oximes: Antidotes to Organophosphate Exposure.
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases
Rational design, synthesis and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase
A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies
Crystallographic studies of human acetylcholinesterase inhibition by organophosphates and reactivation by oximes
Blood‐brain Barrier Penetrant and Orally Bioavailable Antidotes to Organophosphate Poisoning
Planarian cholinesterase: molecular and functional characterization of an evolutionarily ancient enzyme to study organophosphorus pesticide toxicity
Post-exposure treatment with the oxime RS194B rapidly reverses early and advanced symptoms in macaques exposed to sarin vapor
Efficient detoxification of soman, tabun, and VX by oxime assisted reactivation of acetylcholinesterase mutants
Diversity in the binding interactions of marine phycotoxins to AChBP, the soluble nAChR surrogate
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