Irene Pichler
0000-0001-8251-0757
Eurac Research
83 papers found
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Intracellular delivery of Parkin-RING0-based fragments corrects Parkin-induced mitochondrial dysfunction through interaction with SLP-2
An innovative human IPSC-based co-culture model for in vitro studies of neuro-cardiac interactions
A novel human iPSC-based co-culture model to study neurocardiac interaction in vitro
SLP-2 modulated expression rescues mitochondrial function in alpha-synuclein neuropathology models
Deep mitochondrial genotyping reveals altered mitochondrial quality control mechanisms in advanced cellular models of Parkinson’s disease
Induzierte pluripotente Stammzellen als wichtiges Tool in der biomedizinischen Forschung
Progressive mitochondrial DNA damage in Parkinson’s disease induced pluripotent stem cell-derived neurons
Deep mitochondrial genotyping in advanced cellular models of Parkinson’s disease indicates altered mitochondrial quality control mechanisms
Transcriptomic profiling of PRKN-mutant neurons differentiated in a 3D alginate hydrogel matrix
Semiconducting polymer bio-hybrid interfaces: an introductory bioelectrical investigation
Mitochondrial DNA heteroplasmy distinguishes disease manifestation in PINK1/PRKN-linked Parkinson’s disease
Molecular phenotypes of mitochondrial dysfunction in clinically non-manifesting heterozygous PRKN variant carriers
Modulation of SLP-2 expression protects against alpha-synuclein neuropathology by mitigating mitochondrial dysfunction
Crosstalk of organelles in Parkinson’s disease – MiT family transcription factors as central players in signaling pathways connecting mitochondria and lysosomes
Evaluation of a novel in vitro neurocardiac cellular model for the study of heart disorders
SLP-2 protects SNpc DA neurons against alpba-synuclein toxicity by rescuing mitochondrial functions in a mouse model of Parkinson's disease
A genome on shaky ground: exploring the impact of mitochondrial DNA integrity on Parkinson’s disease by highlighting the use of cybrid models
Set-up of a novel in vitro neurocardiac cell model for the in-depth study of heart disease
Generation and characterization of induced pluripotent stem cell (iPSC) lines of two asymptomatic individuals carrying a heterozygous exon 7 deletion in Parkin (PRKN) and two non-carriers from the same family
Generation of an induced pluripotent stem cell line (EURACi014-A) from a Parkinson’s disease patient with an A53T mutation in the SNCA gene by an integration-free reprogramming method
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