Michael Johnson - Dissemin

Papers authored by Michael Johnson

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2016 Tina L. Mistry, Lena Truong, Arun K. Ghosh, Michael E. Johnson

, Shahila Mehboob

Benzimidazole-Based FabI Inhibitors: A Promising Novel Scaffold for Anti-staphylococcal Drug Development

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Amy J. Rice, Hao Lei, Bernard D. Santarsiero, Hyun Lee

, Michael E. Johnson

Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase)

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2015 Pin-Chih Su, Michael E. Johnson

Evaluating thermodynamic integration performance of the new amber molecular dynamics package and assess potential halogen bonds of enoyl-ACP reductase (FabI) benzimidazole inhibitors

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Hao Lei, Christopher Jones, Tian Zhu, Kavankumar Patel, Nina M. Wolf, Leslie W.-M. Fung, Hyun Lee

, Michael E. Johnson

Identification of B. anthracis N5-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening

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Amy J. Rice, Jerry K. Woo, Attiya Khan

, Michael Z. Szypulinski, Michael E. Johnson

, Hyunwoo Lee

, Hyun Lee

Over-expression, purification, and confirmation of Bacillus anthracis transcriptional regulator NprR

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Pin-Chih Su, Cheng-Chieh Tsai, Shahila Mehboob, Kirk E. Hevener, Michael E. Johnson

Comparison of radii sets, entropy, QM methods, and sampling on MM-PBSA, MM-GBSA, and QM/MM-GBSA ligand binding energies of F . tularensis enoyl-ACP reductase (FabI)

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Kevin McClay, Shahila Mehboob, Jerry Yu, Bernard D. Santarsiero, Jiangping Deng, James L. Cook, Hyunyoung Jeong, Michael E. Johnson

, Robert J. Steffan

Indole trimers with antibacterial activity against Gram-positive organisms produced using combinatorial biocatalysis

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Anna Kim, Nina M. Wolf, Tian Zhu, Michael E. Johnson

, Jiangping Deng, James L. Cook, Leslie W.-M. Fung

Identification of Bacillus anthracis PurE inhibitors with antimicrobial activity

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This paper is made freely available by the publisher.

Hyun Lee

, Hao Lei, Bernard D. Santarsiero, Joseph L. Gatuz, Shuyi Cao, Amy J. Rice, Kavankumar Patel, Michael Z. Szypulinski, Isabel Ojeda, Arun K. Ghosh, Michael E. Johnson

Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV

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Shahila Mehboob, Jinhua Song, Kirk E. Hevener, Pin-Chih Su, Teuta Boci, Libby Brubaker, Lena Truong, Tina Mistry, Jiangping Deng, James L. Cook, Bernard D. Santarsiero, Arun K. Ghosh, Michael E. Johnson

Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI)

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Anuradha Mittal, Michael E. Johnson

Conformational diversity of bacterial FabH: Implications for molecular recognition specificity

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2014 Nina M. Wolf, Celerino Abad-Zapatero, Michael E. Johnson

, Leslie W.-M. Fung

Structures of SAICAR synthetase (PurC) fromStreptococcus pneumoniaewith ADP, Mg²⁺, AIR and Asp. Corrigendum

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Micheal L. Tuntland, Bernard D. Santarsiero, Michael E. Johnson

, Leslie W.-M. Fung

Elucidation of the bicarbonate binding site and insights into the carboxylation mechanism of (N⁵)-carboxyaminoimidazole ribonucleotide synthase (PurK) fromBacillus anthracis

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Kelly L. Sullivan, Loredana C. Huma, Elwood A. Mullins, Michael E. Johnson

, T. Joseph Kappock

Metal stopping reagents facilitate discontinuous activity assays of the de novo purine biosynthesis enzyme PurE

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2013 Hyun Lee

, Anuradha Mittal, Kavankumar Patel, Joseph L. Gatuz, Lena Truong, Jaime Torres, Debbie C. Mulhearn, Michael E. Johnson

Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

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Yan-Yan Zhang, Yong Liu, Shahila Mehboob, Jin-Hua Song, Teuta Boci, Michael E. Johnson

, Arun K. Ghosh, Hyunyoung Jeong

Metabolism-directed structure optimization of benzimidazole-basedFrancisella tularensisenoyl-reductase (FabI) inhibitors

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Hyun Lee

, Tian Zhu, Kavankumar Patel, Yan Zhang, Lena Truong, Kirk E. Hevener, Joseph L. Gatuz, Gitanjali Subramanya, Hyun-Young Jeong, Susan L. Uprichard, Michael E. Johnson

High-Throughput Screening (HTS) and Hit Validation to Identify Small Molecule Inhibitors with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes

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Hyun Lee

, Shuyi Cao, Kirk E. Hevener, Lena Truong, Joseph L. Gatuz, Kavankumar Patel, Arun K. Ghosh, Michael E. Johnson

Synergistic Inhibitor Binding to the Papain-Like Protease of Human SARS Coronavirus – Mechanistic and Inhibitor Design Implications

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Amy J. Rice, Lena Truong, Michael E. Johnson

, Hyun Lee

A colorimetric assay optimization for high-throughput screening of dihydroorotase by detecting ureido groups

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Kevin McClay, Baojie Wan, Yuehong Wang, Sanghyun Cho, Jerry Yu, Bernard Santarsiero, Shahila Mehboob, Michael Johnson

, Scott Franzblau, Robert Steffan

A novel combinatorial biocatalytic approach for producing antibacterial compounds effective against Mycobacterium tuberculosis (TB)

Download from link.springer.com

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Papers authored by Michael Johnson