Siddhant U. Jain - Dissemin

All papers authored by Siddhant U. Jain

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2020 Siddhant U. Jain

, Sima Khazaei

, Dylan M. Marchione

, Stefan M. Lundgren, Xiaoshi Wang, Daniel N. Weinberg

, Shriya Deshmukh

, Nikoleta Juretic

, Chao Lu, C. David Allis

, Benjamin A. Garcia, Nada Jabado, Peter W. Lewis

Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression

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This paper was not found in any repository, but could be made available legally by the author.

Sima Khazaei, Nicolas De Jay, Shriya Deshmukh, Liam D. Hendrikse

, Wajih Jawhar

, Carol C. L. Chen

, Leonie G. Mikael, Damien Faury, Dylan M. Marchione

, Joel Lanoix, Éric Bonneil

, Takeaki Ishii, Siddhant U. Jain

, Kateryna Rossokhata, Tianna S. Sihota

and 16 other authors

H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone

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2019 Peder J. Lund, Andrew Q. Rashoff, Nikoleta Juretic, Sriram Venneti, Tom W. Muir, Truman J. Do

, Peter W. Lewis, Katharine L. Diehl, Marcin Cieslik, Andrea Bajic

, Siddhant U. Jain

, Shriya Deshmukh, Benjamin A. Garcia, Nada Jabado

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

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Krupa S. Jani, Stefan M. Lundgren, Manuel M. Müller, Peter W. Lewis, Tom W. Muir, Eva J. Ge, Katharine L. Diehl, Siddhant U. Jain

Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase

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Stephen L. McDaniel, Katharine N. Schulz, Markus Nevil, Peter W. Lewis, Kenneth S. Zaret, Tyler J. Gibson, Meilin Fernandez Garcia, Siddhant U. Jain

, Melissa M. Harrison

Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation

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Ashot S. Harutyunyan

, Brian Krug, Simon Papillon-Cavanagh, Michele Zeinieh, Haifen Chen, Leonie G. Mikael, Nicolas De Jay, Dylan M. Marchione, Shriya Deshmukh, Rui Li, Hamid Nikbakht, Carol C. L. Chen

, Jad Belle, Abdulshakour Mohammadnia, Bo Hu and 18 other authors

H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis

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This paper is available in a repository.

2016 Jill Bayliss

, Piali Mukherjee, Chao Lu, Daniel Martinez, Benjamin Sabari, Ashley S. Margol, Pooja Panwalkar, Abhijit Parolia, Melike Pekmezci, Richard C. McEachin, Chan Chung

, Siddhant U. Jain

, Benita Tamrazi, Gaspare La Rocca, Mariarita Santi and 10 other authors

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas

Download from www.ncbi.nlm.nih.gov

Hariharan Jayaram, Dominik Hoelper

, Siddhant U. Jain

, Stefan M. Lundgren, Nico Cantone, Florence Poy, C. David Allis, Richard Cummings, Steven Bellon, Peter W. Lewis

S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3

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Chao Lu, Rosalynn C. Molden, Leili Ran, Dominik Hoelper

, Devan Murphy, Sriram Venneti, Denise Bechet, Siddhant U. Jain

, Bruce R. Pawel, Jay S. Wunder, Stefan M. Lundgren, Meera Hameed, Krupa S. Jani, Brendan C. Dickson, Simon Papillon-Cavanagh and 15 other authors

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape

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2014 Zachary Z. Brown, Manuel M. Müller, Manuel M. Mueller, Siddhant U. Jain

, C. David Allis, Peter W. Lewis, Tom W. Muir, C. David Allis

Strategy for “Detoxification” of a Cancer-Derived Histone Mutant Based on Mapping Its Interaction with the Methyltransferase PRC2

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All papers authored by Siddhant U. Jain