Darren M. Riddy
www.linkedin.com
0000-0003-0524-1498
Monash Institute of Pharmaceutical Sciences
16 papers found
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Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors
Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms
Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents
New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery
Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists
Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research
G Protein–Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus
Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma
Isoform-Specific Biased Agonism of Histamine H3Receptor Agonists
Fevipiprant (QAW039) a slowly dissociating CRTh2 antagonist with the potential for improved clinical efficacy.
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor Antagonists
Investigating the molecular mechanisms through which FTY720‐P causes persistent S1P1 receptor internalization
QAW039, a slowly dissociating CRTh2 antagonist with potential for improved clinical efficacy
Reassessment of the pharmacology of Sphingosine‐1‐phosphate S1P3 receptor ligands using the DiscoveRx PathHunter™ and Ca2+ release functional assays
A prospective study of isolated human hepatocyte function following liver resection for colorectal liver metastases: The effects of prior exposure to chemotherapy
Effect of alosetron and tegaserod at the 5-HT2B receptor in human colon
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