Ryuichi Ohgaki - Dissemin

All papers authored by Ryuichi Ohgaki

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2023 Yongchan Lee, Chunhuan Jin, Ryuichi Ohgaki

, Minhui Xu, Satoshi Ogasawara, Rangana Warshamanage, Keitaro Yamashita, Garib Murshudov, Osamu Nureki, Takeshi Murata, Yoshikatsu Kanai

Structural basis of anticancer drug recognition and amino acid transport by LAT1

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2022 Kou Nishikubo

, Ryuichi Ohgaki

, Hiroki Okanishi, Suguru Okuda

, Minhui Xu, Hitoshi Endou, Yoshikatsu Kanai

Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells

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Takafumi Kato, Tsukasa Kusakizako, Chunhuan Jin, Xinyu Zhou, Ryuichi Ohgaki

, LiLi Quan, Minhui Xu, Suguru Okuda, Kan Kobayashi, Keitaro Yamashita

, Tomohiro Nishizawa

, Yoshikatsu Kanai

, Osamu Nureki

Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2

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2021 Takafumi Kato, Tsukasa Kusakizako, Chunhuan Jin, LiLi Quan, Ryuichi Ohgaki

, Suguru Okuda, Kan Kobayashi, Keitaro Yamashita, Tomohiro Nishizawa, Yoshikatsu Kanai, Osamu Nureki

Structural insights into human excitatory amino acid transporter EAAT2

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2020 Hiroki Okanishi, Ryuichi Ohgaki

, Suguru Okuda, Hitoshi Endou, Yoshikatsu Kanai

Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor

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Lili Quan, Ryuichi Ohgaki

, Saori Hara, Suguru Okuda, Ling Wei, Hiroki Okanishi, Shushi Nagamori, Hitoshi Endou, Yoshikatsu Kanai

Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation

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Keisuke Jimbo

, Toshiaki Okuno

, Ryuichi Ohgaki

, Kou Nishikubo

, Yuri Kitamura, Yumiko Sakurai, Lili Quan, Hiromichi Shoji

, Yoshikatsu Kanai, Toshiaki Shimizu, Takehiko Yokomizo

A novel mutation in the SLCO2A1 gene, encoding a prostaglandin transporter, induces chronic enteropathy

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This paper was not found in any repository, but could be made available legally by the author.

Chunhuan Jin, Ling Wei, Ryuichi Ohgaki

, Hideyuki Tominaga, Minhui Xu, Suguru Okuda, Hiroki Okanishi, Yasuharu Kawamoto, Xin He, Shushi Nagamori, Yoshikatsu Kanai

Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes

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2019 Yongchan Lee

, Pattama Wiriyasermkul, Chunhuan Jin, Lili Quan, Ryuichi Ohgaki

, Suguru Okuda, Tsukasa Kusakizako, Tomohiro Nishizawa

, Kazumasa Oda, Ryuichiro Ishitani, Takeshi Yokoyama, Takanori Nakane

, Mikako Shirouzu, Hitoshi Endou, Shushi Nagamori and 2 other authors

Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc

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Junji Miyabe, Ryuichi Ohgaki

, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai

Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter

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Ryuichi Ohgaki

, Yuji Teramura, Daichi Hayashi, Shushi Nagamori, Madoka Takai, Yoshikatsu Kanai

Cell surface pH imaging using poly(ethylene glycol)-phospholipid: its potential as the core structure of membrane anchored-probes

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2017 Ryuichi Ohgaki

, Yuji Teramura, Daichi Hayashi, Lili Quan, Suguru Okuda, Shushi Nagamori, Madoka Takai, Yoshikatsu Kanai

Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate

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Ryuichi Ohgaki

, Takahiro Ohmori, Saori Hara, Saya Nakagomi, Masami Kanai-Azuma, Kazuko Kaneda-Nakashima, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai

Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc

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Pornparn Kongpracha, Shushi Nagamori, Pattama Wiriyasermkul, Yoko Tanaka, Kazuko Kaneda, Suguru Okuda, Ryuichi Ohgaki

, Yoshikatsu Kanai

Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1)

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2016 Dora Tarlungeanu, Dora C. Tărlungeanu, Elena Deliu, Christoph P. Dotter, Majdi Kara, Philipp Christoph Janiesch, Mariafrancesca Scalise, Michele Galluccio

, Mateja Tesulov, Emanuela Morelli, Fatma Mujgan Sönmez, Kaya Bilgüvar, Ryuichi Ohgaki

, Yoshikatsu Kanai, Anide Johansen and 10 other authors

Impaired amino acid transport at the blood brain barrier is a cause of autism spectrum disorder

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R. Ohgaki

, L. Wei, K. Yamada, T. Hara, C. Kuriyama, S. Okuda, K. Ueta, M. Shiotani, S. Nagamori, Y. Kanai

Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 inhibitor Canagliflozin with SGLT1 and SGLT2

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Ling Wei, Hideyuki Tominaga, Ryuichi Ohgaki

, Pattama Wiriyasermkul, Kohei Hagiwara, Suguru Okuda, Kyoichi Kaira, Yukio Kato, Noboru Oriuchi, Shushi Nagamori, Yoshikatsu Kanai

Transport of 3-fluoro-l-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [18F]FAMT positron emission tomography

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Shushi Nagamori, Pattama Wiriyasermkul, Meritxell Espino Guarch, Hirohisa Okuyama, Saya Nakagomi, Kenjiro Tadagaki, Yumiko Nishinaka, Susanna Bodoy, Kazuaki Takafuji, Suguru Okuda, Junko Kurokawa, Ryuichi Ohgaki

, Virginia Nunes, Manuel Palacín

, Yoshikatsu Kanai

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1

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Shushi Nagamori, Pattama Wiriyasermkul, Suguru Okuda, Naoto Kojima, Yoshiyuki Hari, Shigeki Kiyonaka, Yasuo Mori, Hideyuki Tominaga, Ryuichi Ohgaki

, Yoshikatsu Kanai

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling

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Ling Wei, Hideyuki Tominaga, Ryuichi Ohgaki

, Pattama Wiriyasermkul, Kohei Hagiwara, Suguru Okuda, Kyoichi Kaira, Noboru Oriuchi, Shushi Nagamori, Yoshikatsu Kanai

Specific transport of 3-fluoro- l -α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging

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All papers authored by Ryuichi Ohgaki