Zhude Tu - Dissemin

All papers authored by Zhude Tu

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2024 Lin Qiu

, Hao Jiang, Kevin Cho

, Yanbo Yu, Lynne A. Jones, Tianyu Huang

, Joel S. Perlmutter, Robert J. Gropler, Matthew R. Brier, Gary J. Patti

, Tammie L. S. Benzinger, Zhude Tu

Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

2021 Hao Jiang, Sumit Joshi, Hui Liu, Syahir Mansor, Lin Qiu, Haiyang Zhao, Timothy Whitehead, Robert J. Gropler, Gregory F. Wu, Anne H. Cross, Tammie L. S. Benzinger, Kooresh I. Shoghi, Joel S. Perlmutter, Zhude Tu

In Vitro and In Vivo Investigation of S1PR1 Expression in the Central Nervous System Using [³H]CS1P1 and [¹¹C]CS1P1

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2020 Lin Qiu, Lixia Du, Qianwa Liang, Hongzhen Hu, Zhude Tu

Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents

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Hui Liu, Zonghua Luo, Jiwei Gu, Yi Su, Hubert Flores, Stanley M. Parsons, Yun Zhou, Joel S. Perlmutter, Zhude Tu

The impact of dopamine D2-like agonist/antagonist on [18F]VAT PET measurement of VAChT in the brain of nonhuman primates

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2019 Yanbo Yu

, Qianwa Liang, Hui Liu

, Zonghua Luo

, Hongzheng Hu, Joel S. Perlmutter, Zhude Tu

Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain

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2018 Xuyi Yue

, Zonghua Luo, Hui Liu, Kota Kaneshige, Stanley M. Parsons, Joel S. Perlmutter, Zhude Tu

Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter

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Chia-Ju Hsieh

, John J. Ferrie, Kuiying Xu, Iljung Lee, Thomas J. A. Graham, Zhude Tu

, Jennifer Yu, Dhruva Dhavale, Paul Kotzbauer, E. James Petersson, Robert H. Mach

Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules

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This paper is made freely available by the publisher.

Chia-Ju Hsieh

, Kuiying Xu, Iljung Lee, Thomas J. A. Graham, Zhude Tu

, Dhruva Dhavale, Paul Kotzbauer, Robert H. Mach

Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro

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Zonghua Luo

, Adam J. Rosenberg

, Hui Liu, Junbin Han, Zhude Tu

Syntheses and in vitro evaluation of new S1PR1 compounds and initial evaluation of a lead F-18 radiotracer in rodents

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Hongjun Jin, Xuyi Yue

, Hui Liu, Junbin Han, Hubert Flores, Yi Su, Stanley M. Parsons, Joel S. Perlmutter, Zhude Tu

Kinetic modeling of [¹⁸F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non‐human primate brain

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Hui Liu, Hongjun Jin, Zonghua Luo, Xuyi Yue

, Xiang Zhang, Hubert Flores, Yi Su, Joel S. Perlmutter, Zhude Tu

In Vivo Characterization of Two 18F-Labeled PDE10A PET Radioligands in Nonhuman Primate Brains

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Zonghua Luo

, Xuyi Yue

, Hao Yang, Hui Liu, Robyn S. Klein, Zhude Tu

Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands

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Hongjun Jin, Junbin Han, Derek Resing, Hui Liu, Xuyi Yue

, Rebecca L. Miller, Kathleen M. Schoch, Timothy M. Miller, Joel S. Perlmutter, Terrance M. Egan, Zhude Tu

Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease

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Zonghua Luo

, Junbin Han, Hui Liu

, Adam J. Rosenberg

, Delphine L. Chen, Robert J. Gropler, Joel S. Perlmutter

, Zhude Tu

Syntheses and in vitro biological evaluation of S1PR1 ligands and PET studies of four F-18 labeled radiotracers in the brain of nonhuman primates

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2017 Hui Liu, Hongjun Jin, Junbin Han, Xuyi Yue

, Hao Yang, Mohamed A. Zayed, Robert J. Gropler, Zhude Tu

Upregulated Sphingosine 1-Phosphate Receptor 1 Expression in Human and Murine Atherosclerotic Plaques

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Junbin Han, Hui Liu

, Chunling Liu, Hongjun Jin, Joel S. Perlmutter, Terrance M. Egan, Zhude Tu

Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response:

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Xuyi Yue

, Hongjun Jin, Zonghua Luo, Hui Liu

, Xiang Zhang, Ethan D. McSpadden, Linlin Tian, Hubert P. Flores, Joel S. Perlmutter, Stanley M. Parsons, Zhude Tu

Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (−)-[18F]TZ3108 in rodent and the nonhuman primate brain

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Xuyi Yue

, Hongjun Jin, Hui Liu

, Zonghua Luo

, Xiang Zhang, Kota Kaneshige, Hubert P. Flores, Joel S. Perlmutter

, Stanley M. Parsons, Zhude Tu

Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate

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Hui Liu

, Hongjun Jin, Xuyi Yue

, Junbin Han, Pamela Baum, Dana R. Abendschein, Zhude Tu

PET Study of Sphingosine-1-Phosphate Receptor 1 Expression in Response to Vascular Inflammation in a Rat Model of Carotid Injury

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2016 Paul T. Kotzbauer

, Zhude Tu

, Robert H. Mach

Current status of the development of PET radiotracers for imaging alpha synuclein aggregates in Lewy bodies and Lewy neurites

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All papers authored by Zhude Tu