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All papers authored by Omar Khan

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2023 Jennifer E. Wu

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, Sasikanth Manne

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, Shin Foong Ngiow

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, Amy E. Baxter

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, Hua Huang, Elizabeth Freilich

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, Megan L. Clark

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, Joanna H. Lee

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, Zeyu Chen, Omar Khan

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, Ryan P. Staupe

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, Yinghui J. Huang

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, Josephine R. Giles

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, E. John Wherry

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In vitro modeling of CD8 ⁺ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40

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2022 Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, Amy E. Baxter

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, Omar Khan

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, Ping Wang, Ryan Staupe, Mohamed S. Abdel-Hakeem

ORCID

, Hua Huang, Divij Mathew, Mark M. Painter

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, Jennifer E. Wu, Yinghui Jane Huang

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, Rishi R. Goel, Patrick K. Yan and 5 other authors

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

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2021 Zeyu Chen, Eri Arai, Omar Khan

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, Zhen Zhang, Shin Foong Ngiow

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, Yuan He, Hua Huang, Sasikanth Manne, Zhendong Cao, Amy E. Baxter

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, Zhangying Cai, Elizabeth Freilich, Mohammed A. Ali, Josephine R. Giles, Jennifer E. Wu and 13 other authors

In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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2020 Jean-Christophe Beltra, Sasikanth Manne, Mohamed S. Abdel-Hakeem, Makoto Kurachi, Josephine R. Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan

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, Yinghui Jane Huang, Patrick Yan, Kito Nzingha, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu and 5 other authors

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

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2019 Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C. Huang, John Johnson, Ryan P. Staupe, Bertram Bengsch, Caiyue Xu, Sixiang Yu, Makoto Kurachi, Ramin S. Herati, Laura A. Vella, Amy E. Baxter and 12 other authors

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision

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Omar Khan

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, Josephine R. Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P. Patel, Michael T. Werner, Alexander C. Huang, Katherine A. Alexander, Jennifer E. Wu, John Attanasio, Patrick Yan, Sangeeth M. George, Bertram Bengsch, Ryan P. Staupe and 10 other authors

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

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Chen Yao, Hong-Wei Sun, Neal E. Lacey

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, Yun Ji, E. Ashley Moseman, Han-Yu Shih

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, Elisabeth F. Heuston, Martha Kirby

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, Stacie Anderson, Jun Cheng, Omar Khan

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, Robin Handon, Julie Reilley, Jessica Fioravanti

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, Jinhui Hu and 7 other authors

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

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2018 Bertram Bengsch, Takuya Ohtani, Omar Khan

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, Manu Setty, Sasikanth Manne, Shaun O’Brien, Pier Federico Gherardini, Ramin Sedaghat Herati, Alexander C. Huang, Kyong-Mi Chang, Evan W. Newell, Niels Bovenschen, Dana Pe’er, Steven M. Albelda, E. John Wherry

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

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2017 Zeyu Chen, Erietta Stelekati, Makoto Kurachi, Sixiang Yu, Zhangying Cai, Sasikanth Manne, Omar Khan

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, Xiaolu Yang, E. John Wherry, E. John Wherry

miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb

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Makoto Kurachi, Junko Kurachi, Zeyu Chen, John Johnson, Omar Khan

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, Bertram Bengsch, Erietta Stelekati, John Attanasio, Laura M. McLane, Michio Tomura, Satoshi Ueha, E. John Wherry

Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function

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2016 Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan

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, Adam M. Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel and 4 other authors

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

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2013 Audrey Gérard, Omar Khan

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, Peter Beemiller, Erin Oswald, Joyce Hu, Mehrdad Matloubian, Matthew F. Krummel

Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells

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2011 Omar Khan

ORCID

, Mark Headley, Audrey Gerard, Wei Wei, Limin Liu, Matthew F. Krummel

Regulation of T Cell Priming by Lymphoid Stroma

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