All papers authored by Omar Khan
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Sasikanth Manne ,
Shin Foong Ngiow ,
Amy E. Baxter ,
Hua Huang,
Elizabeth Freilich ,
Megan L. Clark ,
Joanna H. Lee ,
Zeyu Chen,
Omar Khan ,
Ryan P. Staupe ,
Yinghui J. Huang ,
Junwei Shi ,
Josephine R. Giles ,
E. John Wherry
In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40
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Omar Khan ,
Ping Wang,
Ryan Staupe,
Mohamed S. Abdel-Hakeem ,
Hua Huang,
Divij Mathew,
Mark M. Painter ,
Jennifer E. Wu,
Yinghui Jane Huang ,
Rishi R. Goel,
Patrick K. Yan
and 5 other authors
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Zhen Zhang,
Shin Foong Ngiow ,
Yuan He,
Hua Huang,
Sasikanth Manne,
Zhendong Cao,
Amy E. Baxter ,
Zhangying Cai ,
Elizabeth Freilich,
Mohammed A. Ali,
Josephine R. Giles,
Jennifer E. Wu
and 13 other authors
In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
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Makoto Kurachi,
Josephine R. Giles,
Zeyu Chen,
Valentina Casella,
Shin Foong Ngiow,
Omar Khan ,
Yinghui Jane Huang,
Patrick Yan,
Kito Nzingha,
Wei Xu,
Ravi K. Amaravadi,
Xiaowei Xu
and 5 other authors
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Alexander C. Huang,
John Johnson,
Ryan P. Staupe,
Bertram Bengsch,
Caiyue Xu,
Sixiang Yu,
Makoto Kurachi,
Ramin S. Herati,
Laura A. Vella,
Amy E. Baxter
and 12 other authors
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
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Josephine R. Giles,
Sierra McDonald,
Sasikanth Manne,
Shin Foong Ngiow,
Kunal P. Patel,
Michael T. Werner,
Alexander C. Huang,
Katherine A. Alexander,
Jennifer E. Wu,
John Attanasio,
Patrick Yan,
Sangeeth M. George,
Bertram Bengsch,
Ryan P. Staupe
and 10 other authors
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
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Yun Ji,
E. Ashley Moseman,
Han-Yu Shih ,
Elisabeth F. Heuston,
Martha Kirby ,
Stacie Anderson,
Jun Cheng,
Omar Khan ,
Robin Handon,
Julie Reilley,
Jessica Fioravanti ,
Jinhui Hu
and 7 other authors
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
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Sasikanth Manne,
Omar Khan ,
Xiaolu Yang,
E. John Wherry,
E. John Wherry
miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb
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Bertram Bengsch,
Erietta Stelekati,
John Attanasio,
Laura M. McLane,
Michio Tomura,
Satoshi Ueha,
E. John Wherry
Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function
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Adam M. Drake,
Zeyu Chen,
Debattama R. Sen,
Makoto Kurachi,
R. Anthony Barnitz,
Caroline Bartman ,
Bertram Bengsch,
Alexander C. Huang,
Jason M. Schenkel
and 4 other authors
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
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Omar Khan ,
Peter Beemiller,
Erin Oswald,
Joyce Hu,
Mehrdad Matloubian,
Matthew F. Krummel
Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells
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Mark Headley,
Audrey Gerard ,
Wei Wei,
Limin Liu,
Matthew F. Krummel
Regulation of T Cell Priming by Lymphoid Stroma
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