Leonardo Pardo - Dissemin

Papers authored by Leonardo Pardo

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2007 Carolina P. Reyes, Francisco Muñoz-Martínez, Ivan R. Torrecillas, Cristina R. Mendoza, Francisco Gamarro, Isabel L. Bazzocchi, Marvin J. Núñez, Leonardo Pardo

, Santiago Castanys, Mercedes Campillo, Ignacio A. Jiménez

Biological Evaluation, Structure−Activity Relationships, and Three-Dimensional Quantitative Structure−Activity Relationship Studies of Dihydro-β-agarofuran Sesquiterpenes as Modulators of P-Glycoprotein-Dependent Multidrug Resistance

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Jean-Yves Springael, Cédric de Poorter, Xavier Deupi

, Joost Van Durme, Leonardo Pardo

, Marc Parmentier

The activation mechanism of chemokine receptor CCR5 involves common structural changes but a different network of interhelical interactions relative to rhodopsin.

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This paper was not found in any repository, but could be made available legally by the author.

Xavier Deupi

, Nicole Dolker, Maria Luz Lopez-Rodriguez

, Mercedes Campillo, Juan A. Ballesteros, Leonardo Pardo

Structural Models of Class A G Protein-Coupled Receptors as a Tool for Drug Design: Insights on Transmembrane Bundle Plasticity

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Elisa Pérez-Sacau, Raquel G. Díaz Peñate, Ana Estévez-Braun, Angel G. Ravelo, Jose M. García Castellano, Leonardo Pardo

, Mercedes Campillo

Synthesis and Pharmacophore Modeling of Naphthoquinone Derivatives with Cytotoxic Activity in Human Promyelocytic Leukemia HL-60 Cell Line

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Martine J. Smit, Henry F. Vischer, Remko A. Bakker, Aldo Jongejan, Henk Timmerman, Leonardo Pardo

, Rob Leurs

Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity

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2006 Leonardo Pardo

, Xavier Deupi

, Nicole Doelker, Nicole Dölker, María Luz López-Rodríguez

, Mercedes Campillo

The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors

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This paper is made freely available by the publisher.

Dennis Verzijl, Leonardo Pardo

, Marie van Dijk, Yvonne K. Gruijthuijsen, Aldo Jongejan, Henk Timmerman, John Nicholas, Mario Schwarz, Philip M. Murphy, Rob Leurs, Martine J. Smit

Helix 8 of the Viral Chemokine Receptor ORF74 Directs Chemokine Binding

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2005 Wei Xu, J. Kim de Riel, Mercedes Campillo, Leonardo Pardo

, J. Kim de Riel, Lee-Yuan Liu-Chen

The SEVENTH TRANSMEMBRANE DOMAINS OF THE δ AND κ OPIOID RECEPTORS HAVE DIFFERENT ACCESSIBILITY PATTERNS AND INTERHELICAL INTERACTIONS†

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F. Cortes-Selva, I. Jimenez, F. Munoz-Martinez, M. Campillo, I. Bazzocchi, L. Pardo

, A. Ravelo, S. Castanys, F. Gamarro

Dihidro-β-Agarofuran Sesquiterpenes: A New Class of Reversal Agents of the Multidrug Resistance Phenotype Mediated by P-Glycoprotein in the Protozoan Parasite Leishmania

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Aldo Jongejan, Martijn Bruysters, Juan A. Ballesteros, Eric Haaksma, Remko A. Bakker, Leonardo Pardo

, Rob Leurs

Linking agonist binding to histamine H1 receptor activation

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

María L. López-Rodríguez

, Maria José Morcillo, Esther Fernández, Bellinda Benhamú, Ignacio Tejada, David Ayala, Alma Viso

, Mercedes Campillo, Leonardo Pardo

, Mercedes Delgado, Jorge Manzanares, José A. Fuentes

Synthesis and Structure−Activity Relationships of a New Model of Arylpiperazines. 8.1Computational Simulation of Ligand−Receptor Interaction of 5-HT1AR Agonists with Selectivity over α1-Adrenoceptors

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2004 Lucia Montanelli, Joost J. J. Van Durme, Guillaume Smits, Marco Bonomi, Patrice Rodien, Eric J. Devor, Kristin Moffat-Wilson, Leonardo Pardo

, Gilbert Vassart, Sabine Costagliola

Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.

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Xavier Deupi, Mireia Olivella, Cedric Govaerts, Juan Antonio Ballesteros, Mercedes Campillo, Leonardo Pardo

Ser and Thr Residues Modulate the Conformation of Pro-Kinked Transmembrane α-Helices

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2003 David Bosch, Mercedes Campillo, Leonardo Pardo

Binding of proteins to the minor groove of DNA: What are the structural and energetic determinants for kinking a basepair step?

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Marı́a L. López-Rodrı́guez

, Ma José Morcillo, Esther Fernández, Bellinda Benhamú, Ignacio Tejada, David Ayala, Alma Viso

, Mireia Olivella, Leonardo Pardo

, Mercedes Delgado, Jorge Manzanares, José A. Fuentes

Design and synthesis of S-(−)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist

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2002 Cédric Govaerts, Antoine Bondue, Jean-Yves Springael, Mireia Olivella, Xavier Deupi

, Emmanuel Le Poul, Emmanuel Le Poul, Shoshana J. Wodak, Marc Parmentier, Leonardo Pardo

, Cédric Blanpain

Activation of CCR5 by Chemokines Involves an Aromatic Cluster between Transmembrane Helices 2 and 3

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Mireia Olivella, Xavier Deupi, Cedric Govaerts, Leonardo Pardo

Influence of the Environment in the Conformation of α-Helices Studied by Protein Database Search and Molecular Dynamics Simulations

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Sylvie Claeysen, Cédric Govaerts, Anne Lefort, Jacqueline Van Sande, Sabine Costagliola, Leonardo Pardo

, Gilbert Vassart

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

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2001 Marı́a L. López-Rodrı́guez

, Marta Murcia, Bellinda Benhamú, Alma Viso

, Mercedes Campillo, Leonardo Pardo

3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT4 receptor

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Cédric Govaerts, Anne Lefort, Sabine Costagliola, Shoshana J. Wodak, Juan Antonio Ballesteros, Jacqueline Van Sande, Leonardo Pardo

, Gilbert Vassart

A conserved Asn in transmembrane helix 7 is an on/off switch in the activation of the thyrotropin receptor.

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Papers authored by Leonardo Pardo