David Bishop
0000-0001-6415-1455
Westmead Institute for Medical Research
16 papers found
Refreshing results…
Development of CAR T-cell lymphoma in 2 of 10 patients effectively treated withpiggyBac-modified CD19 CAR T cells
CAR T Cell Generation by piggyBac Transposition from Linear Doggybone DNA Vectors Requires Transposon DNA-Flanking Regions
Allogeneic stem cell transplant (HSCT) for acute lymphoblastic leukaemia (ALL) using CD34 selected stem cells followed by prophylactic infusions of pathogen-specific and CD19 CAR T cells
Matched sibling donor-derived piggybac CAR19 T cells induce remission of relapsed/refractory CD19+ malignancy following haematopoietic stem cell transplant
PiggyBac-Engineered T Cells Expressing CD19-Specific CARs that Lack IgG1 Fc Spacers Have Potent Activity against B-ALL Xenografts
Tumour microenvironment modulates cart cell fate in paediatric leukemia
shRNA-mediated TCR knockdown as a foundation for allogeneic CAR19 T-cells generated by single-step genetic modification with the piggyBac transposase
Factors promoting CD19-negative relapses following CAR19T cell therapy
Imaging the dynamics of receptor-modified T cell effector function against leukaemia and neuroblastoma targets
Long-term control of recurrent or refractory viral infections after allogeneic HSCT with third-party virus-specific T cells
Abstract 3760: Preclinical optimization of a low cost PiggyBac transposase (PB) generated CD19-specific chimeric antigen receptor T cell (CART19) product for a first in man trial using local hospital cell manufacture
Differing co-stimulatory, linker and spacer domains produce variations in CD4 and CD8 cell composition and cytotoxic potential in CD19-specific chimeric antigen receptor (CAR19) T cells generated with the piggyBac transposase
Low-cost generation of Good Manufacturing Practice–grade CD19-specific chimeric antigen receptor–expressing T cells using piggyBac gene transfer and patient-derived materials
449. Multipathogen-Specific T Cells for Immune Reconstitution – A Decade of Manufacturing Development and Clinical Use
Haploidentical peripheral blood stem cell infusion in combination with chemotherapy for acute myeloid leukaemia in elderly patients
The LIM Protein FHL3 Binds Basic Kruppel-like Factor/Kruppel-like Factor 3 and Its Co-repressor C-terminal-binding Protein 2
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