Niels Heise - Dissemin

All papers authored by Niels Heise

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2024 Niels V. Heise

Dehydroabietylamine derived bistetrazoles from ultrasound-assisted pseudo-seven-component Ugi reactions act as efficient and selective inhibitors of cholinesterases

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2023 Niels Heise

, Florian Lehmann, René Csuk

, Thomas Mueller

Targeted theranostics: Near-infrared triterpenoic acid-rhodamine conjugates as prerequisites for precise cancer diagnosis and therapy

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This paper is made freely available by the publisher.

Niels V. Heise

, Toni C. Denner, Selina Becker, Sophie Hoenke

, René Csuk

Developing an Amide-Spacered Triterpenoid Rhodamine Hybrid of Nano-Molar Cytotoxicity Combined with Excellent Tumor Cell/Non-Tumor Cell Selectivity

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Julia Heisig, Niels V. Heise

, Sophie Hoenke, Ahmed Al-Harrasi, René Csuk

In search of cytotoxic abietyl amides

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Niels Heise

, Selina Becker, Thomas Mueller

, Matthias Bache, René Csuk

, Antje Güttler

Mitochondria-Targeting 1,5-Diazacyclooctane-Spacered Triterpene Rhodamine Conjugates Exhibit Cytotoxicity at Sub-Nanomolar Concentration against Breast Cancer Cells

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Julia Heisig, Niels V. Heise

, Sophie Hoenke

, Dieter Ströhl, René Csuk

The Finally Rewarding Search for A Cytotoxic Isosteviol Derivative

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Anastasiya V. Petrova

, Oxana B. Kazakova

, Ivan S. Nazarov

, René Csuk

, Niels V. Heise

Acetylcholinesterase Inhibitory Activity of Modified Lupane, Oleanane, and Ursane A‐seco‐Triterpenoids

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Oliver Kraft, Anne-Kathrin Hartmann, Sarah Brandt, Sophie Hoenke, Niels V. Heise

, René Csuk

, Thomas Mueller

Asiatic acid as a leading structure for derivatives combining sub-nanomolar cytotoxicity, high selectivity, and the ability to overcome drug resistance in human preclinical tumor models

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Oxana Kazakova

, Irina Smirnova, Ha Thi Thu Nguyen, Niels V. Heise

, Sophie Hoenke, Immo Serbian, René Csuk

α-Glucosidase and cholinesterase inhibiting potential of a series of semisynthetic nitrogen triterpenic derivatives

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Toni C. Denner

, Niels Heise

, Julian Zacharias, Oliver Kraft

, Sophie Hoenke

, René Csuk

Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates

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Niels V. Heise

, Julia Heisig, Linda Höhlich, Sophie Hoenke, René Csuk

Synthesis and cytotoxicity of diastereomeric benzylamides derived from maslinic acid, augustic acid and bredemolic acid

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Júnio G. Silva, Tatiane F. Borgati, Samuel M. G. Lopes, Niels Heise

, Sophie Hoenke, René Csuk, Luiz C. A. Barbosa

New amides derived from sclareolide as anticholinesterase agents

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2022 Niels V. Heise

, Sophie Hoenke, Immo Serbian

, René Csuk

An improved partial synthesis of corosolic acid and its conversion to highly cytotoxic mitocans

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Niels V. Heise

, Jördis-Ann Schüler

, Torje E. Orlamünde, Benjamin Brandes, Hans-Peter Deigner, Ahmed Al-Harrasi, René Csuk

Triterpenoid cholinesterase inhibitors that might improve gait disturbances in Parkinson's disease patients

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Oliver Kraft, Gregor C. Mittag, Sophie Hoenke, Niels Heise

, Ahmed Al-Harrasi, René Csuk

Synthesis and characterization of steroidal, anellated aminothiophenes by Gewald reaction

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Mabrouk Horchani, Niels V. Heise

, René Csuk

, Hichem Ben Jannet

, Abdel Halim Harrath

, Anis Romdhane

Synthesis and In Silico Docking Study towards M-Pro of Novel Heterocyclic Compounds Derived from Pyrazolopyrimidinone as Putative SARS-CoV-2 Inhibitors

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Niels V. Heise

, Daniel Major, Sophie Hoenke

, Marie Kozubek

, Immo Serbian

, René Csuk

Rhodamine 101 Conjugates of Triterpenoic Amides Are of Comparable Cytotoxicity as Their Rhodamine B Analogs

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Niels V. Heise

, Dieter Ströhl, Theresa Schmidt, René Csuk

Stable triterpenoid iminium salts and their activity as inhibitors of butyrylcholinesterase

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Niels Heise

, Sander Friedrich, Veronika Temml

, Daniela Schuster, Bianka Siewert

, René Csuk

N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase

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All papers authored by Niels Heise