Arvin Iracheta-Vellve

All papers authored by Arvin Iracheta-Vellve

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2023 Christina K. Baumgartner

, Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve

, Keith M. Hamel, Kira E. Olander

, Thomas G. R. Davis, Kathleen A. McGuire, Geoff T. Halvorsen, Omar I. Avila

, Chirag H. Patel, Sarah Y. Kim, Ashwin V. Kammula

, Audrey J. Muscato

, Kyle Halliwill, Prasanthi Geda and 51 other authors

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

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Marcelle de Carvalho Ribeiro

, Arvin Iracheta-Vellve

, Mrigya Babuta

, Charles D. Calenda

, Christopher Copeland

, Yuan Zhuang

, Patrick P. Lowe

, Danielle Hawryluk

, Donna Catalano

, Yeonhee Cho

, Bruce Barton

, Srinivasan Dasarathy

, Craig McClain

, Arthur J. McCullough, Mack C. Mitchell

and 5 other authors

Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation

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This paper is made freely available by the publisher.

Yi Sun, Or-Yam Revach, Seth Anderson

, Emily A. Kessler

, Clara H. Wolfe, Anne Jenney, Caitlin E. Mills

, Emily J. Robitschek, Thomas G. R. Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee

, Payal Tiwari, Peter P. Du

and 44 other authors

Targeting TBK1 to overcome resistance to cancer immunotherapy

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2022 Juan Dubrot, Peter P. Du

, Sarah Kate Lane-Reticker, Emily A. Kessler, Audrey J. Muscato

, Arnav Mehta, Samuel S. Freeman

, Peter M. Allen, Kira E. Olander

, Kyle M. Ockerman

, Clara H. Wolfe, Fabius Wiesmann, Nelson H. Knudsen

, Hsiao-Wei Tsao, Arvin Iracheta-Vellve

and 18 other authors

In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

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2021 Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta-Vellve

, James C. Patti

, Jeffrey Hsu

, Thomas Davis, Deborah Dele-Oni, Peter P. Du

, Aya G. Halawi, Jeffrey J. Ishizuka, Sarah Y. Kim, Susan Klaeger

, Nelson H. Knudsen

, Brian C. Miller

, Tung H. Nguyen and 14 other authors

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

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Juan Dubrot, Sarah Kate Lane-Reticker, Emily A. Kessler

, Austin Ayer, Gargi Mishra, Clara H. Wolfe, Margaret D. Zimmer

, Peter P. Du

, Animesh Mahapatra, Kyle M. Ockerman

, Thomas G. R. Davis, Ian C. Kohnle, Hans W. Pope, Peter M. Allen, Kira E. Olander and 5 other authors

In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

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2020 Patrick P. Lowe, Caroline Morel, Aditya Ambade, Arvin Iracheta-Vellve

, Erica Kwiatkowski, Abhishek Satishchandran, Istvan Furi, Yeonhee Cho, Benedek Gyongyosi, Donna Catalano, Eric Lefebvre, Laurent Fischer, Star Seyedkazemi, Dorothy P. Schafer, Gyongyi Szabo

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

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2019 B. Gyongyosi, Y. Cho, P. Lowe, C. D. Calenda, A. Iracheta-Vellve

, A. Satishchandran, A. Ambade, G. Szabo

Alcohol-induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis, and inflammasome-IL-18 activation in the proximal small intestine in mice

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Xiaojing Wang, Marcelle de Carvalho Ribeiro, Arvin Iracheta‐Vellve

, Patrick Lowe, Aditya Ambade, Abhishek Satishchandran, Terence Bukong, Donna Catalano, Karen Kodys, Gyongyi Szabo

Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

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2018 Jeffrey J. Ishizuka, Robert T. Manguso, Collins K. Cheruiyot, Kevin Bi, Arpit Panda, Arvin Iracheta-Vellve

, Brian C. Miller

, Peter P. Du

, Kathleen B. Yates, Juan Dubrot, Ilana Buchumenski, Dawn E. Comstock, Flavian D. Brown, Austin Ayer, Ian C. Kohnle and 12 other authors

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

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Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve

, Yeonhee Cho, Aditya Ambade, Gyongyi Szabo

Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

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Aditya Ambade, Patrick Lowe, Karen Kodys, Donna Catalano, Benedek Gyongyosi, Yeonhee Cho, Arvin Iracheta Vellve

, Adeyinka Adejumo, Banishree Saha, Charles Calenda, Jeeval Mehta, Eric Lefebvre, Pamela Vig, Gyongyi Szabo

Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol-induced liver damage, steatosis and inflammation in mice

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Terence Ndonyi Bukong, Yeonhee Cho, Arvin Iracheta-Vellve

, Banishree Saha, Patrick Lowe, Adeyinka Adejumo, Istvan Furi, Aditya Ambade, Benedek Gyongyosi, Donna Catalano, Karen Kodys, Gyongyi Szabo

Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use

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Banishree Saha, Fatemeh Momen-Heravi, Istvan Furi, Karen Kodys, Donna Catalano, Anwesha Gangopadhyay, Reka Haraszti

, Abhishek Satishchandran, Arvin Iracheta-Vellve

, Adeyinka Adejumo, Scott A. Shaffer, Gyongyi Szabo

Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation through heat shock protein 90

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This paper is available in a repository.

Abhishek Satishchandran

, Aditya Ambade

, Sitara Rao, Ying-Chao Hsueh, Arvin Iracheta-Vellve

, David Tornai

, Patrick Lowe, Benedek Gyongyosi, Jia Li, Donna Catalano

, Li Zhong, Karen Kodys, Jun Xie

, Shashi Bala, Guangping Gao and 1 other authors

MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease

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2017 Arvin Iracheta-Vellve

, Gyongyi Szabo

IL-1α in acetaminophen toxicity: a sterile danger signal

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Shashi Bala, Timea Csak, Karen Kodys, Donna Catalano, Aditya Ambade, Istvan Furi, Patrick Lowe, Yeonhee Cho, Arvin Iracheta-Vellve

, Gyongyi Szabo

Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

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Arvin Iracheta-Vellve

, Jan Petrasek, Benedek Gyogyosi, Shashi Bala, Timea Csak, Karen Kodys, Gyongyi Szabo

Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice

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Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran, Arvin Iracheta-Vellve

, Aditya Ambade, Karen Kodys, Donna Catalano, Doyle V. Ward, Gyongyi Szabo

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2016 Arvin Iracheta-Vellve

, Jan Petrasek, Benedek Gyongyosi, Abhishek Satishchandran, Patrick Lowe, Karen Kodys, Donna Catalano, Charles D. Calenda, Evelyn A. Kurt-Jones, Kate A. Fitzgerald, Gyongyi Szabo

Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via Stimulator of Interferon Genes.

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All papers authored by Arvin Iracheta-Vellve