David R. Poyner - Dissemin

All papers authored by David R. Poyner

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2022 Abigail Pearce, Theo Redfern-Nichols, Matthew Harris, David R. Poyner

, Mark Wigglesworth, Graham Ladds

Determining the Effects of Differential Expression of GRKs and β-arrestins on CLR-RAMP Agonist Bias

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Ian Winfield, Kerry Barkan, Sarah Routledge, Nathan J. Robertson, Matthew Harris, Ali Jazayeri, John Simms, Christopher A. Reynolds, David R. Poyner

, Graham Ladds

The Role of ICL1 and H8 in Class B1 GPCRs; Implications for Receptor Activation

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2021 Clare R. Harwood, David A. Sykes, Bradley L. Hoare, Franziska M. Heydenreich

, Romez Uddin, David R. Poyner

, Stephen J. Briddon, D. B. Veprintsev

Functional solubilization of the β2-adrenoceptor using diisobutylene maleic acid

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Ashley J. Clark, Niamh Mullooly, Dewi Safitri, Matthew Harris, Tessa de Vries, Antoinette MaassenVanDenBrink, David R. Poyner

, Davide Gianni, Mark Wigglesworth

, Graham Ladds

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

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This paper was not found in any repository, but could be made available legally by the author.

Rachael L. Grime

, Richard T. Logan

, Stephanie A. Nestorow, Pooja Sridhar, Patricia C. Edwards

, Christopher G. Tate, Bert Klumperman

, Tim R. Dafforn, David R. Poyner

, Philip J. Reeves, Mark Wheatley

Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles

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2020 Aiman A. Gulamhussein, Romez Uddin, Brian J. Tighe, David R. Poyner

, Alice J. Rothnie

A comparison of SMA (styrene maleic acid) and DIBMA (di-isobutylene maleic acid) for membrane protein purification

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

C. R. Harwood, D. A. Sykes, B. Hoare, R. Uddin, D. R. Poyner

, D. B. Veprintsev, Franziska M. Heydenreich

, S. J. Briddon

Functional solubilisation of the β2-adrenoceptor (β2AR) using Diisobutylene maleic acid (DIBMA)

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Sarah J. Routledge, Mohammed Jamshad, Haydn A. Little, Yu-Pin Lin, John Simms, Alpesh Thakker, Corinne M. Spickett, Roslyn M. Bill, Tim R. Dafforn, David R. Poyner

, Mark Wheatley

Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

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Daniel N. Wiseman, Abigail Otchere, Jaimin H. Patel, Romez Uddin, Naomi L. Pollock, Sarah J. Routledge, Alice J. Rothnie, Cathy Slack, David R. Poyner

, Roslyn M. Bill, Alan D. Goddard

Expression and purification of recombinant G protein-coupled receptors: A review

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Sarah J. Routledge, John Simms, Ashley Clark, Ho Yan Yeung, Mark J. Wigglesworth, Ian M. Dickerson, Philip Kitchen, Graham Ladds, David R. Poyner

Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors

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Sang-Min Lee, Yejin Jeong, John Simms, Margaret L. Warner, David R. Poyner

, Ka Young Chung, Augen A. Pioszak

Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics

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Rachael L. Grime

, Joelle Goulding

, Romez Uddin

, Leigh A. Stoddart

, Stephen J. Hill

, David R. Poyner

, Stephen J. Briddon

, Mark Wheatley

Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles

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2019 Sian Bailey, Matthew Harris, Kerry Barkan, Ian Winfield, Matthew Thomas Harper, John Simms, Graham Ladds, Mark Wheatley

, David Poyner

Interactions between RAMP2 and CRF receptors: The effect of receptor subtypes, splice variants and cell context

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2018 Romez Uddin, John Simms, David Poyner

Functional characterisation of G protein-coupled receptors

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Marvin V. Dilworth, Mathilde S. Piel, Kim E. Bettaney, Pikyee Ma

, Ji Luo, David Sharples, David R. Poyner

, Stephane R. Gross, Karine Moncoq, Peter J. F. Henderson, Bruno Miroux

, Roslyn M. Bill

Microbial expression systems for membrane proteins

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Duncan I. Mackie

, Fuad Al Mutairi, Reema B. Davis, Daniel O. Kechele

, Natalie R. Nielsen, Joshua C. Snyder, Marc G. Caron, Harvey J. Kliman

, Jonathan S. Berg, John Simms, David R. Poyner

, Kathleen M. Caron

hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia

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John Simms, Romez Uddin, Thomas P. Sakmar, Joseph J. Gingell, Michael L. Garelja, Debbie L. Hay

, Margaret A. Brimble

, Paul W. Harris, Christopher A. Reynolds, David R. Poyner

Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex

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John Simms, Sarah Routledge, Romez Uddin, David Poyner

The Structure of the CGRP and Related Receptors

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2017 Debbie L. Hay

, Michael L. Garelja

, David R. Poyner

, Christopher S. Walker

Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25

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Michael J. Woolley, Christopher A. Reynolds, John Simms, Christopher S. Walker, Juan Carlos Mobarec, Michael L. Garelja, Alex C. Conner, David R. Poyner

, Debbie L. Hay

Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs

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All papers authored by David R. Poyner