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Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM
UploadNUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir
UploadDevelopment of a chemical probe against NUDT15
Download from www.nature.comAuthor Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells
Download from www.nature.comPiperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors
UploadTargeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Download from www.nature.comNUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine
Download from aacrjournals.orgPathways controlling dNTP pools to maintain genome stability
UploadDiscovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Download from www.researchgate.netATM kinase inhibition preferentially sensitizes p53 mutant glioma to ionizing radiation
Download from clincancerres.aacrjournals.orgInhibition of Neurotensin Receptor 1 Selectively Sensitizes Prostate Cancer to Ionizing Radiation
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