Melissa Shi
0000-0003-1454-9566
6 papers found
Refreshing results…
A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells
BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells
Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
Ensemble Properties of Bax Determine Its Function
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