Matthias R. Bauer

All papers authored by Matthias R. Bauer

This paper was not found in any repository, but could be made available legally by the author.

2023 Benjamin C. Whitehurst

, Matthias R. Bauer

, Fredrik Edfeldt, Anders Gunnarsson, Christian Margreitter

, Philip B. Rawlins, R. Ian Storer

Design and Evaluation of a Low Hydrogen Bond Donor Count Fragment Screening Set to Aid Hit Generation of PROTACs Intended for Oral Delivery

Upload

This paper is made freely available by the publisher.

2020 Matthias R. Bauer

, Andreas Krämer, Giovanni Settanni

, Rhiannon N. Jones, Xiaomin Ni, Raysa Khan Tareque, Alan R. Fersht, John Spencer

, Andreas C. Joerger

Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm

Download from pubs.acs.org

2019 Matthias R. Bauer

, Rhiannon N. Jones, Raysa K. Tareque, Bradley Springett, Felix A. Dingler, Lorena Verduci, Ketan J. Patel, Alan R. Fersht, Andreas C. Joerger

, John Spencer

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C

Upload

Sara Gomes

, Bartolomeo Bosco, Joana B. Loureiro, Helena Ramos

, Liliana Raimundo

, Joana Soares, Nair Nazareth, Valentina Barcherini

, Lucília Domingues

, Carla Oliveira

, Alessandra Bisio

, Silvano Piazza

, Matthias R. Bauer

, João P. Brás

, Maria Inês Almeida

and 6 other authors

SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma

Download from doi.org

Matthias R. Bauer

, Mark D. Mackey

Electrostatic Complementarity as a Fast and Effective Tool to Optimize Binding and Selectivity of Protein–Ligand Complexes

Upload

2018 Christopher C. T. Sng

, Sorcha O'Byrne, Daniil M. Prigozhin

, Matthias R. Bauer

, Jennifer C. Harvey, Michelle Ruhle, Ben G. Challis, Sara Lear, Lee D. Roberts, Sarita Workman, Tobias Janowitz

, Lukasz Magiera, Rainer Doffinger, Matthew S. Buckland

, Duncan J. Jodrell and 4 other authors

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway

Upload

This paper is available in a repository.

Matthias G. J. Baud

, Matthias R. Bauer

, Lorena Verduci, Felix A. Dingler, Ketan J. Patel, Deeptee Horil Roy, Andreas C. Joerger, Alan R. Fersht

Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines

Download from publikationen.ub.uni-frankfurt.de

Naoise C. Synnott, Matthias R. Bauer

, Stephen Madden, Alyson Murray, Rut Klinger, Norma O'Donovan, Darran O'Connor

, William M. Gallagher, John Crown, Alan R. Fersht, Michael J. Duffy

Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007

Upload

Esha Madan, Taylor M. Parker, Matthias R. Bauer

, Alisha Dhiman

, Christopher J. Pelham, Masaki Nagane, M. Lakshmi Kuppusamy, Matti Holmes, Thomas R. Holmes, Kranti Shaik, Kevin Shee, Salome Kiparoidze, Sean D. Smith

, Yu-Soon A. Park, Jennifer J. Gomm and 9 other authors

The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53

Download from doi.org

2016 Matthias R. Bauer

, Andreas C. Joerger, Alan R. Fersht

2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells

Download from doi.org

Dennis Bromley, Matthias R. Bauer

, Alan R. Fersht, Valerie Daggett

Anin silicoalgorithm for identifying stabilizing pockets in proteins: test case, the Y220C mutant of the p53 tumor suppressor protein

Download from www.ncbi.nlm.nih.gov

Matthias R. Bauer

, Rhiannon N. Jones, Rainer Wilcken, Frank M. Boeckler, Matthias G. J. Baud

, Alan R. Fersht, Andreas C. Joerger, John Spencer

Harnessing Fluorine–Sulfur Contacts and Multipolar Interactions for the Design of p53 Mutant Y220C Rescue Drugs

Download from pubs.acs.org

2015 Andreas C. Joerger, Matthias R. Bauer

, Rainer Wilcken, Hannes Harbrecht, Thomas E. Exner, Frank M. Boeckler, John Spencer, Alan R. Fersht, Frank Böckler, Matthias Gj J. Baud

Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant p53

Download from dx.doi.org

Tamer M. Ibrahim, Matthias R. Bauer

, Alexander Dörr, Erdem Veyisoglu, Frank M. Boeckler

pROC-Chemotype Plots Enhance the Interpretability of Benchmarking Results in Structure-Based Virtual Screening

Upload

Rainer Wilcken, Markus O. Zimmermann, Matthias R. Bauer

, Trevor J. Rutherford, Alan R. Fersht, Andreas C. Joerger, Frank M. Boeckler

Experimental and Theoretical Evaluation of the Ethynyl Moiety as a Halogen Bioisostere

Download from europepmc.org

Tamer M. Ibrahim, Matthias R. Bauer

, Frank M. Boeckler

Applying DEKOIS 2.0 in structure-based virtual screening to probe the impact of preparation procedures and score normalization

Download from doi.org

2014 Tamer M. Ibrahim, Matthias R. Bauer

, Frank M. Boeckler

Probing the impact of protein and ligand preparation procedures on chemotype enrichment in structure-based virtual screening using DEKOIS 2.0 benchmark sets

Download from dx.doi.org

Frank M. Boeckler, Matthias R. Bauer

, Tamer M. Ibrahim, Simon M. Vogel

Use of DEKOIS 2.0 to gain insights for virtual screening

Download from dx.doi.org

This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Fm Boeckler, R. Wilcken, Mr Bauer

, Mb Cieslik, Tj Rutherford, Ar Fersht, Ac Joerger

Ligand Binding Assays

Upload

Matthias Rupp

, Matthias R. Bauer

, Rainer Wilcken, Andreas Lange, Michael Reutlinger, Frank M. Boeckler, Frank M. Böckler, Gisbert Schneider

Machine Learning Estimates of Natural Product Conformational Energies

Download from dx.doi.org

Missing publications? Search for publications with a matching author name.

Researcher

Statistics

Refine

All papers authored by Matthias R. Bauer