Antonello Caruso - Dissemin

All papers authored by Antonello Caruso

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2021 Paulina Jakubiak

, Rubén Alvarez-Sánchez

, Matthias Fueth, Olaf Broders, Hubert Kettenberger, Kay Stubenrauch, Antonello Caruso

Ocular Pharmacokinetics of Intravitreally Injected Protein Therapeutics: Comparison among Standard-of-Care Formats

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2020 Antonello Caruso

, James R. Faeder, Jannik Vollmer

, Matthias Machacek

, Elod Kortvely

Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease

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Simon Hauri

, Paulina Jakubiak, Matthias Fueth, Stefan Dengl, Sara Belli, Rubén Alvarez-Sánchez, Antonello Caruso

Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin

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Antonello Caruso

, Matthias Füth, Ruben Alvarez-Sánchez

, Sara Belli, Cheikh Diack, Katie F. Maass, Dietmar Schwab, Hubert Kettenberger, Norman A. Mazer

Ocular Half-Life of Intravitreal Biologics in Humans and Other Species: Meta-Analysis and Model-Based Prediction

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2018 Laurence A. Hutton-Smith, Eamonn A. Gaffney, Helen M. Byrne, Antonello Caruso

, Philip K. Maini, Norman A. Mazer

Theoretical Insights into the Retinal Dynamics of Vascular Endothelial Growth Factor in Patients Treated with Ranibizumab, Based on an Ocular Pharmacokinetic/Pharmacodynamic Model

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2016 Mark Davies, Ken Wang, Antonello Caruso

, Gary Mirams, Denis Noble, Antje Walz, Thierry Lave, Franz Schuler, Thomas Singer, Liudmila Polonchuk

What are the challenges and opportunities ahead of any regulatory requirements for in silico cardiac pro-arrhythmia prediction?

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Thierry Lavé, Antonello Caruso

, Neil Parrott, Antje Walz

Translational PK/PD modeling to increase probability of success in drug discovery and early development

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Ken Wang, Mark Davies, Antonello Caruso

, Gary Mirams, Denis Noble, Antje-Christine Walz, Thierry Lavé, Franz Schuler, Thomas Singer, Liudmila Polonchuk

Importance of parameter control in cardiac models for robust pro-arrhythmic risk prediction

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Ken Wang, Gary Mirams, Mark Davies, Antonello Caruso

, Denis Noble, Ruben Alvarez-Sanchez, Antje Christine Walz, Thierry Lave, Franz Schuler, Thomas Singer, Liudmila Polonchuk

Simulation of L-Type Calcium Currents using Different Experimental Data Sources: from Cell Line to iPS-Derived Cardiomyocyte

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Mark R. Davies

, Ken Wang, Gary R. Mirams

, Antonello Caruso

, Denis Noble, Antje Walz, Thierry Lavé, Franz Schuler, Thomas Singer, Liudmila Polonchuk

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

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2014 Antje‐Christine Walz, Hans Peter Grimm, Christophe Meille, Antonello Caruso

, Neil Parrott, Thierry Lavé

Role of Modeling and Simulation in Toxicology Prediction

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Helmut Jacobsen, Laurence Ozmen, Antonello Caruso

, Robert Narquizian, Hans Hilpert, Bjoern Jacobsen

, Dick Terwel

, An Tanghe, Bernd Bohrmann

Combined Treatment with a BACE Inhibitor and Anti-Aβ Antibody Gantenerumab Enhances Amyloid Reduction in APP_LondonMice

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Antonello Caruso

, Nicolas Frances, Christophe Meille, Andrea Greiter-Wilke, Alexander Hillebrecht, Thierry Lave

Translational PK/PD Modeling for Cardiovascular Safety Assessment of Drug Candidates: Methods and Examples in Drug Development.

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2013 Antonello Caruso

, Ruben Alvarez-Sánchez, Alexander Hillebrecht, Agnès Poirier, Franz Schuler, Thierry Lavé, Christoph Funk, Sara Belli

PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation

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2012 Aki T. Heikkinen, Guillaume Baneyx, Antonello Caruso

, Neil Parrott

Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates – An evaluation and case study using GastroPlus™

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Leon M. Tai, Helmut Jacobsen, Laurence Ozmen, Alexander Flohr, Roland Jakob-Roetne, Antonello Caruso

, Hans-Peter Grimm

The dynamics of Aβ distribution after γ-secretase inhibitor treatment, as determined by experimental and modelling approaches in a wild type rat

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2011 Alexander Koenig, Antonello Caruso

, Marc Bolliger, Luca Somaini, Ximena Omlin, Manfred Morari, Robert Riener

Model-based heart rate control during robot-assisted gait training

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2009 Antonello L. G. Caruso

, Manfred Morari

Model Predictive Control for Propofol Sedation

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2008 Antonello L. G. Caruso

, Thomas W. Bouillon, Peter M. Schumacher, Manfred Morari

On the modeling of drug induced respiratory depression in the non-steady-state

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2007 Antonello L. G. Caruso

, Thomas W. Bouillon, Peter M. Schumacher, Martin Luginbuhl, Manfred Morari

Drug-induced respiratory depression: An integrated model of drug effects on the hypercapnic and hypoxic drive

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All papers authored by Antonello Caruso