Andrew Purkiss
0000-0002-5931-3509
The Francis Crick Institute
4 papers found
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Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1
Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis
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