Ian Blagbrough
0000-0003-0307-4999
University of Nottingham
113 papers found
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Efficient Calf Thymus DNA Condensation upon Binding with Novel Bile Acid Polyamine Amides
Design and synthesis of unsymmetrical polyamine spermidine and spermine conjugates with potential in DNA binding and non-viral gene therapy studies.
[H-3]-methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors
Lipopolyamines incorporating the tetraamine spermine, bound to an alkyl chain, sequester bacterial lipopolysaccharide
Cheno-, Urso- and Deoxycholic Acid Spermine Conjugates: Relative Binding Affinities for Calf Thymus DNA
Homologation of Polyamines in the Rapid Synthesis of Lipospermine Conjugates and Related Lipoplexes
Synthesis of cholesteryl polyamine carbamates: pK(a) studies and condensation of calf thymus DNA
Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy
The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection
A novel solid-phase reductive alkylation route to acridine and dansyl polyamine conjugates
Characterisation of the binding of [H-3]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors
An autoradiographic study of the distribution of binding sites for the novel alpha 7-selective nicotinic radioligand [H-3]methyllycaconitine in the mouse brain
Extracellular or intracellular application of argiotoxin-636 has inhibitory actions on membrane excitability and voltage-activated currents in cultured rat sensory neurones
Studies on the substituted 3-aminopropan-1-ol motif of lycoctonine class norditerpenoid alkaloids: A novel route to 3-hydroxymethylcyclohex-2-enone
Synthesis of C5-substituted AE-bicyclic analogues of lycoctonine, inuline and methyllycaconitine
Synthesis of cholesterol-polyamine carbamates: pK(a) studies and condensation of calf thymus DNA (pg 1403, 1998)
Synthesis of cholesterol-polyamine carbamates: pKa studies and condensation of calf thymus DNA
Electrorheological behaviour at low applied electric fields of microcrystalline cellulose in BP oils
Practical synthesis of unsymmetrical polyamine amides
Spermine and thermine conjugates of cholic acid condense DNA, but lithocholic acid polyamine conjugates do so more efficiently
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