John Schneekloth - Dissemin

All papers authored by John Schneekloth

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2022 Christopher D. Sibley, John S. Schneekloth

Heterobifunctional molecules tackle targeted protein dephosphorylation

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2021 Monalisa Swain, Abeer A. Ageeli, Wojciech K. Kasprzak, Mi Li, Jennifer T. Miller, Joanna Sztuba-Solinska

, John S. Schneekloth

, Deepak Koirala, Joseph Piccirili, Americo J. Fraboni, Ryan P. Murelli, Alexander Wlodawer, Bruce A. Shapiro, Nathan Baird

, Stuart F. J. Le Grice

Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands

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Xue Zhi Zhao

, Evgeny Kiselev, George T. Lountos

, Wenjie Wang, Joseph E. Tropea, Danielle Needle, Thomas A. Hilimire, John S. Schneekloth

, David S. Waugh, Yves Pommier, Terrence R. Burke

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites

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2020 Sreejana Ray, Desiree Tillo

, Robert E. Boer, Nima Assad, Mira Barshai, Guanhui Wu, Yaron Orenstein, Danzhou Yang

, John S. Schneekloth

, Charles Vinson

Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes

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Robert E. Boer, Zachary R. Torrey, John S. Schneekloth

Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems

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2019 William M. Hewitt, David R. Calabrese, John S. Schneekloth

Evidence for ligandable sites in structured RNA throughout the Protein Data Bank

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Colleen M. Connelly, Tomoyuki Numata, Robert E. Boer, Michelle H. Moon, Ranu S. Sinniah, Joseph J. Barchi, Adrian R. Ferré-D’Amaré

, John S. Schneekloth

Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

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Fardokht A. Abulwerdi

, Wenbo Xu, Abeer A. Ageeli, Michael J. Yonkunas, Gayatri Arun, Hyeyeon Nam, John S. Schneekloth

, Theodore Kwaku Dayie, David Spector, Nathan Baird

, Stuart F. J. Le Grice

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

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2018 David R. Calabrese, Xiang Chen, Elena C. Leon, Snehal M. Gaikwad, Zaw Phyo, William M. Hewitt, Stephanie Alden, Thomas A. Hilimire, Fahu He, Aleksandra M. Michalowski, John K. Simmons, Lindsey B. Saunders, Shuling Zhang, Daniel Connors, Kylie J. Walters and 2 other authors

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex

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Pengcheng Yan

, Daniel A. Ritt, Katherine Zlotkowski, Heidi R. Bokesch

, William C. Reinhold

, John S. Schneekloth

, Deborah K. Morrison

, Kirk R. Gustafson

Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling

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Sara N. Journey, Stephanie L. Alden, Will M. Hewitt, Megan L. Peach

, Marc C. Nicklaus

, John S. Schneekloth Jr

Probing the hras-1Y i-motif with small molecules

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2017 Katherine Zlotkowski, William M. Hewitt, Pengcheng Yan, Heidi R. Bokesch, Megan L. Peach

, Marc C. Nicklaus, Barry R. O’Keefe, James B. McMahon, Kirk R. Gustafson

, John S. Schneekloth

Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina

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2016 Colleen M. Connelly, Robert E. Boer, Michelle H. Moon, Peter Gareiss, John S. Schneekloth

Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays

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Fardokht A. Abulwerdi, Matthew D. Shortridge, Joanna Sztuba-Solinska, Robert Wilson, Stuart F. J. Le Grice, Gabriele Varani, John S. Schneekloth

Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA

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All papers authored by John Schneekloth