Kara-Louise Royle

All papers authored by Kara-Louise Royle

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2022 Amy Beth Coulson

, Kara-Louise Royle

, Charlotte Pawlyn, David A. Cairns, Anna Hockaday, Jennifer Bird, Stella Bowcock

, Martin Kaiser, Ruth de Tute, Neil Rabin, Kevin Boyd, John Jones, Christopher Parrish, Hayley Gardner, David Meads and 10 other authors

Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial

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2021 J. E. Brown, K.-L. Royle

, C. Ralph, D. Meads, A. Martin, H. Howard, C. Linsley, J. Swain, T. B. Powles, R. Jones, T. Eisen, A. Maraveyas, R. Griffiths, O. Din, V. Goh and 5 other authors

LBA28 STAR: A randomised multi-stage phase II/III trial of standard first-line therapy (sunitinib or pazopanib) comparing temporary cessation with allowing continuation, in the treatment of locally advanced and/or metastatic renal Cancer (RCC)

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Kara-Louise Royle

, David A. Cairns

The development and validation of prognostic models for overall survival in the presence of missing data in the training dataset: a strategy with a detailed example

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2019 David Cairns, Charlotte Pawlyn, Kara-Louise Royle

, Phillip Best, Jenny Bird, Stella Bowcock, Kevin Boyd, Bryony Dawkins, Mark T. Drayson, Rowena Henderson, Matthew Jenner, John R. Jones, Martin F. Kaiser, Bhuvan Kishore, David Meads and 5 other authors

Frailty-Adjusted Therapy in Transplant Non-Eligible Patients with Newly Diagnosed Multiple Myeloma (FiTNEss): A UK Myeloma Research Alliance Study, Myeloma XIV

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Charlotte Pawlyn, Faith E. Davies, Kara-Louise Royle

, David Cairns, Gordon Cook, Mark T. Drayson, Walter M. Gregory, Matthew Jenner, John R. Jones, Martin F. Kaiser, Roger G. Owen, Nigel H. Russell, Gareth Morgan, Graham Jackson

Lenalidomide Maintenance Prolongs Progression-Free Survival and Does Not Impact the Aggressiveness of Clinical Relapse: Data from Long-Term Follow up of the Myeloma XI Trial

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Gordon Cook, Kara-Louise Royle

, Charlotte Pawlyn, Anna Hockaday, Vallari Shah, Martin F. Kaiser, Sarah R. Brown, Walter M. Gregory, J. Anthony Child, Faith E. Davies, Gareth J. Morgan, David A. Cairns, Graham H. Jackson

A clinical prediction model for outcome and therapy delivery in transplant-ineligible patients with myeloma (UK Myeloma Research Alliance Risk Profile): a development and validation study

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Curly Morris, Kara-Louise Royle

, Sheila O'Connor, A. John Ashcroft, Cathy D. Williams, John A. Snowden, Eleni Tholouli, Christopher Parrish, Kwee Yong, Guy Pratt, Treen C. M. Morris, David Cairns, Anna Hockaday, Jamie D. Cavenagh, Debo Ademokun and 8 other authors

The impact of cytogenetics on duration of response and overall survival in patients with relapsed multiple myeloma (long-term follow-up results from BSBMT/UKMF Myeloma X Relapse [Intensive]): a randomised, open-label, phase 3 trial.

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2018 Kara-Louise Royle

, Walter M. Gregory, David A. Cairns

, Sue E. Bell, Gordon Cook, Roger G. Owen, Mark T. Drayson, Faith E. Davies, Graham H. Jackson, Gareth J. Morgan, J. Anthony Child

Quality of life during and following sequential treatment of previously untreated patients with multiple myeloma: findings of the Medical Research Council Myeloma IX randomised study

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2017 Gordon Cook, Kara-Louise Royle

, Charlotte Pawlyn, Anna Hockaday, Walter M. Gregory, J. Anthony Child, Faith E. Davies, Gareth J. Morgan, David Cairns, Graham Jackson

The Leeds Risk Profile Predicts Outcome for Older Myeloma Patients: A Prognostic Score Using Frailty Biomarkers Derived and Tested Using 2371 Clinical Trial Patients

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C. Kelly Morland, J. Zhong, V. Goh, T. Wah, Christy Ralph, F. Thistlethwaite, P. Patel, P. Nathan, T. Eisen, Walter Gregory, L. McParland, H. Cool, Kara-Louise Royle

, E. Best, L. Whincup and 2 other authors

Prospective comparison of RECIST and alternative response assessment criteria in the evaluation of metastatic renal cell cancer patients from phase II of the multi-centre randomised STAR trial

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David Cairns, Kara-Louise Royle

, Walter Gregory, Sue Bell, Gordon Cook, Roger Owen, Mark Drayson, Faith Davies, Gareth Morgan, Graham Jackson, James Child

The Impact of Thalidomide, Zoledronate and High-dose Therapy with Autologous Stem Cell Support on Patient Reported Outcomes in Multiple Myeloma: Results of the Quality of Life Substudy of the MRC Myeloma IX Randomised Controlled Trial

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1970 Kara-Louise Royle

, Adam Martin, David Meads, Walter Gregory, Lucy McParland

P-103: Considerations for statistical analysis when QALYs are a co-primary endpoint in a large phase II/III randomised controlled trial

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All papers authored by Kara-Louise Royle