Simon E. Ward
0000-0002-8745-8377
Cardiff University
83 papers found
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3, 4-Dihydro-2H-benzoxazinones as dual-acting 5-HT 1A receptor antagonists and serotonin reuptake inhibitors
Synthetic studies towards garsubellin A: synthesis of model systems and potential mimics by regioselective lithiation of bicyclo[3.3.1]nonane-2,4,9-trione derivatives from catechinic acid
Synthetic studies towards garsubellin A: synthesis of model systems and potential mimics by regioselective lithiation of bicyclo [3.3. 1] nonane-2, 4, 9-trione derivatives from catechinic acid
Studies on a series of potent, orally bioavailable, 5-HT 1 receptor ligands
Stereoselective Synthesis of (-)-Trachelanthamidine via Palladium-Catalysed Intramolecular Allylation
Piperidine and piperazine derivatives possessing affinity at 5HT-1 type receptors
Discovery of the First Potent, Selective 5-Hydroxytryptamine1D Receptor Antagonist
(-)-Mefloquine as a starting point for the discovery of selective adenosine A (2A) receptor antagonists
Multiple 5-HT approaches to novel anti-depressants
Stereoselective γ-lactam synthesis via palladium-catalysed intramolecular allylation
Evaluation of analogues of (-)-mefloquine as adenosine A (2A) receptor antagonists.
1-(Adamantyl) amidines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
Particularly adenosine A2A receptors; neurodegenerative disorders; 2, 8-bis (trifluoromethyl)-alpha-(3-thienyl)-4-quinolinemethanol
2-adamantanemethanamine compounds for treating abnormalities in glutamatergic transmission
2-Methyl-5-(2-${$4-[3-(1-methylpiperidin-4-yl) benzyl] piperidin-1-yl$}$ ethoxy) quinoline hydrochloride; antagonist of 5-serotonin (HT) 1 type receptors; antidepressant and anxiolytic agent
Compound possessing affinity at 5ht1-type receptors and use thereof in therapy of cns disorders
Such as 3, 5-dimethyl-1-adamantanecarboximidamide hydrochloride; glutamate receptors; methyl-D-aspartate receptors; neurodegenerative diseases; side effect reduction
Biodistribution of a radiolabelled monoclonal antibody NY3D11 recognizing the neural cell adhesion molecule in tumour xenografts and patients with small-cell lung cancer.
A novel synthesis of tert-leucine via a Leuckart type reaction
Total synthesis of carbocyclic nikkomycin C
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